Colorectal leukotriene B4 synthesis in vitro in inflammatory bowel disease: inhibition by the selective 5-lipoxygenase inhibitor BWA4C

scientific article published on April 1, 1992

Colorectal leukotriene B4 synthesis in vitro in inflammatory bowel disease: inhibition by the selective 5-lipoxygenase inhibitor BWA4C is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1136/GUT.33.4.513
P8608Fatcat IDrelease_jpuctvlm7rfwfigibn2kwwmmcy
P953full work available at URLhttps://europepmc.org/articles/PMC1374069
https://europepmc.org/articles/PMC1374069?pdf=render
https://gut.bmj.com/content/gutjnl/33/4/513.full.pdf
https://syndication.highwire.org/content/doi/10.1136/gut.33.4.513
P932PMC publication ID1374069
P698PubMed publication ID1316305
P5875ResearchGate publication ID21840013

P2093author name stringC. J. Hawkey
B. J. Whittle
N. K. Boughton-Smith
A. B. Hawthorne
P2860cites workSelective inhibition of arachidonate 5-lipoxygenase by novel acetohydroxamic acids: effects on bronchial anaphylaxis in anaesthetized guinea-pigsQ28361518
A simplification of the protein assay method of Lowry et al. which is more generally applicableQ29615220
In vivo effects of orally administered prednisolone on prostaglandin and leucotriene production in ulcerative colitisQ34528633
The effect of anti-inflammatory drugs on eicosanoid formation in a chronic model of inflammatory bowel disease in the rat.Q35755471
Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease.Q41268129
Failure of the inhibition of rat gastric mucosal 5-lipoxygenase by novel acetohydroxamic acids to prevent ethanol-induced damageQ41847644
Biosynthesis of lipoxygenase and cyclo-oxygenase products from [14C]-arachidonic acid by human colonic mucosaQ41868286
Selective inhibition of arachidonate 5-lipoxygenase by novel acetohydroxamic acids: biochemical assessment in vitro and ex vivoQ42543352
Chemotactic activity in inflammatory bowel disease. Role of leukotriene B4.Q43485535
An orally active inhibitor of leukotriene synthesis accelerates healing in a rat model of colitisQ43830308
Lipoxin A4 and lipoxin B4 inhibit chemotactic responses of human neutrophils stimulated by leukotriene B4 and N-formyl-L-methionyl-L-leucyl-L-phenylalanineQ44126336
Leukotriene B4 potentiates colonic ulceration in the rat.Q44997864
Modulation of human colonic arachidonic acid metabolism by sulfasalazine.Q54440774
Participation of thromboxane and other eicosanoid synthesis in the course of experimental inflammatory colitisQ57241249
Relationship between arachidonic acid metabolism, myeloperoxidase activity and leukocyte infiltration in a rat model of inflammatory bowel diseaseQ69842461
Enhanced formation of sulfidopeptide-leukotrienes in ulcerative colitis and Crohn's disease: inhibition by sulfasalazine and 5-aminosalicylic acidQ69886676
Possible mode of action of 5-aminosalicylic acidQ69910198
Hapten-induced model of chronic inflammation and ulceration in the rat colonQ69942171
Effects of topical 5-aminosalicylic acid and prednisolone on prostaglandin E2 and leukotriene B4 levels determined by equilibrium in vivo dialysis of rectum in relapsing ulcerative colitisQ70146099
Enhanced synthesis of leukotriene B4 by colonic mucosa in inflammatory bowel diseaseQ70184508
Release of leukotriene C4 from human polymorphonuclear leucocytes as determined by radioimmunoassayQ71628611
Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster modelsQ72397450
Inhibition of leukotriene biosynthesis by the leukocyte product 15-hydroxy-5,8,11,13-eicosatetraenoic acidQ72868762
VARIATION BETWEEN OBSERVERS IN DESCRIBING MUCOSAL APPEARANCES IN PROCTOCOLITISQ76593193
Quantitative assay for acute intestinal inflammation based on myeloperoxidase activityQ114866262
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectinflammatory bowel diseasesQ917447
benzeneacetamidesQ77836850
P304page(s)513-517
P577publication date1992-04-01
P1433published inGutQ5621669
P1476titleColorectal leukotriene B4 synthesis in vitro in inflammatory bowel disease: inhibition by the selective 5-lipoxygenase inhibitor BWA4C
P478volume33

Reverse relations

cites work (P2860)
Q84694544Activity of the leukotriene pathway in Barrett's metaplasia and oesophageal adenocarcinoma
Q43075788Attenuation of inflammation and cytokine production in rat colitis by a novel selective inhibitor of leukotriene A4 hydrolase.
Q85316391Communication between mast cells and rat submucosal neurons
Q34376938Effect of Helicobacter pylori colonisation on gastric mucosal eicosanoid synthesis in patients taking non-steroidal anti-inflammatory drugs
Q72161402Effect of leukotriene C4D4 antagonist on colonic damage induced by intracolonic administration of trinitrobenzene sulfonic acid in rats
Q34376929Enhanced gastric mucosal leukotriene B4 synthesis in patients taking non-steroidal anti-inflammatory drugs
Q33781057Genes involved in the metabolism of poly-unsaturated fatty-acids (PUFA) and risk for Crohn's disease in children & young adults
Q41562983Inhibition of cell proliferation and glutathione S-transferase by ascorbyl esters and interferon in mouse glioma
Q41084494Lactadherin orthologs inhibit migration of human, porcine and murine intestinal epithelial cells.
Q34410221Mucosal factors inducing neutrophil movement in ulcerative colitis: the role of interleukin 8 and leukotriene B4.
Q43225463Role of biliary stenting in the management of bile duct stones in the elderly
Q38014899The medicinal chemistry of stable synthetic leukotriene B(3) and B(4) analogues

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