scholarly article | Q13442814 |
P50 | author | Valentina Masola | Q30513702 |
Gianluigi Zaza | Q37635234 | ||
Maurizio Onisto | Q60966024 | ||
P2093 | author name string | Samuel N Heyman | |
Antonio Lupo | |||
Israel Vlodavsky | |||
Neta Ilan | |||
Preeti Singh | |||
Edward Hammond | |||
Iyad Khamaysi | |||
Zaid Abassi | |||
Shadi Hamoud | |||
Ahmad Hassan | |||
Gloria Bellin | |||
Omri Nativ | |||
Rabia Shekh Muhammad | |||
Giovani Gambaro | |||
P2860 | cites work | Acute renal failure: definitions, diagnosis, pathogenesis, and therapy | Q24563291 |
Subendothelial heparan sulfate proteoglycans become major L-selectin and monocyte chemoattractant protein-1 ligands upon renal ischemia/reperfusion | Q24683770 | ||
Unexpected new roles for heparanase in Type 1 diabetes and immune gene regulation | Q27009264 | ||
PG545, a heparan sulfate mimetic, reduces heparanase expression in vivo, blocks spontaneous metastases and enhances overall survival in the 4T1 breast carcinoma model | Q27327191 | ||
Impact of heparanase on renal fibrosis | Q28083753 | ||
Endothelin: 20 years from discovery to therapy | Q28292494 | ||
Heparanase in glomerular diseases | Q28303555 | ||
Newly generated heparanase knock-out mice unravel co-regulation of heparanase and matrix metalloproteinases | Q28475274 | ||
Functions of cell surface heparan sulfate proteoglycans | Q29618521 | ||
Cathepsin L is responsible for processing and activation of proheparanase through multiple cleavages of a linker segment | Q33331276 | ||
Versatile role of heparanase in inflammation | Q33770777 | ||
In vivo fragmentation of heparan sulfate by heparanase overexpression renders mice resistant to amyloid protein A amyloidosis | Q33772163 | ||
Heparanase levels are elevated in the urine and plasma of type 2 diabetes patients and associate with blood glucose levels | Q33834001 | ||
Renal response to tissue injury: lessons from heme oxygenase-1 GeneAblation and expression | Q33894514 | ||
Heparanase: a key enzyme involved in cell invasion | Q34183747 | ||
Pathophysiology of ischemic acute renal failure | Q34275833 | ||
Elevated urine heparanase levels are associated with proteinuria and decreased renal allograft function | Q34426913 | ||
PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models | Q34627931 | ||
Mammalian heparanase: what is the message? | Q34652072 | ||
Signaling mechanisms of the epithelial-mesenchymal transition | Q35213019 | ||
Cellular pathophysiology of ischemic acute kidney injury | Q35484725 | ||
Recent data concerning heparanase: focus on fibrosis, inflammation and cancer | Q35836200 | ||
Heparanase: A Potential New Factor Involved in the Renal Epithelial Mesenchymal Transition (EMT) Induced by Ischemia/Reperfusion (I/R) Injury | Q36088435 | ||
Significance of heparanase in cancer and inflammation | Q36101233 | ||
Role of endothelin in fibrosis and anti-fibrotic potential of bosentan | Q36132271 | ||
Signaling pathway cooperation in TGF-β-induced epithelial-mesenchymal transition | Q36311752 | ||
Macrophage activation by heparanase is mediated by TLR-2 and TLR-4 and associates with plaque progression | Q36542354 | ||
Regulation, function and clinical significance of heparanase in cancer metastasis and angiogenesis | Q36562440 | ||
Role of endothelin and endothelin receptor antagonists in renal disease | Q36570855 | ||
Novel pharmacological approaches to the treatment of renal ischemia-reperfusion injury: a comprehensive review | Q37014196 | ||
Heparanase mediates renal dysfunction during early sepsis in mice. | Q37411095 | ||
Heparanase is required for activation and function of macrophages. | Q37473740 | ||
The role of heparanase in diseases of the glomeruli | Q37668171 | ||
Acute kidney injury: lessons from experimental models | Q37830991 | ||
Early growth response gene 1 (EGR1) regulates heparanase gene transcription in tumor cells. | Q38322333 | ||
Endothelin and tubulointerstitial renal disease | Q38475442 | ||
Heparanase: a rainbow pharmacological target associated to multiple pathologies including rare diseases | Q38801721 | ||
Heparanase is a key player in renal fibrosis by regulating TGF-β expression and activity | Q38983916 | ||
Heparanase: roles in cell survival, extracellular matrix remodelling and the development of kidney disease | Q39120713 | ||
Role of heparanase-driven inflammatory cascade in pathogenesis of diabetic nephropathy | Q39162263 | ||
Tubular epithelial syndecan-1 maintains renal function in murine ischemia/reperfusion and human transplantation | Q39413604 | ||
Acute kidney injury, mortality, length of stay, and costs in hospitalized patients | Q39730814 | ||
Heparanase is essential for the development of diabetic nephropathy in mice. | Q39782778 | ||
Regulation of glomerular heparanase expression by aldosterone, angiotensin II and reactive oxygen species. | Q39853500 | ||
Endothelin-1 Induces Proteinuria by Heparanase-Mediated Disruption of the Glomerular Glycocalyx | Q39879255 | ||
Increased expression of heparanase in puromycin aminonucleoside nephrosis | Q40778136 | ||
Inducible expression of Egr-1-dependent genes. A paradigm of transcriptional activation in vascular endothelium | Q41604083 | ||
Mechanisms of heparanase inhibition by the heparan sulfate mimetic PG545 and three structural analogues | Q41817665 | ||
Heparanase: From basic research to therapeutic applications in cancer and inflammation | Q42587945 | ||
Transgenic expression of mammalian heparanase uncovers physiological functions of heparan sulfate in tissue morphogenesis, vascularization, and feeding behavior | Q44760488 | ||
Heparanase-1 gene expression and regulation by high glucose in renal epithelial cells: a potential role in the pathogenesis of proteinuria in diabetic patients | Q46570573 | ||
The road from AKI to CKD: the role of endothelin | Q46709379 | ||
Heparanase is involved in the pathogenesis of proteinuria as a result of glomerulonephritis | Q47298666 | ||
Experimental ischemia-reperfusion: biases and myths-the proximal vs. distal hypoxic tubular injury debate revisited. | Q53060383 | ||
Induction of glomerular heparanase expression in rats with adriamycin nephropathy is regulated by reactive oxygen species and the renin-angiotensin system. | Q53606143 | ||
Acute renal failure | Q54139071 | ||
Heparanase inhibition reduces proteinuria in a model of accelerated anti-glomerular basement membrane antibody disease. | Q54664919 | ||
Heparanase Is Essential for the Development of Acute Experimental Glomerulonephritis | Q57789449 | ||
Gene expression for endothelins and their receptors in glomeruli of diabetic rats | Q72855454 | ||
Identification of Neutrophil Gelatinase-Associated Lipocalin as a Novel Early Urinary Biomarker for Ischemic Renal Injury | Q79091417 | ||
Increased expression of heparanase in overt diabetic nephropathy | Q79272921 | ||
A synthetic heparanase inhibitor reduces proteinuria in passive Heymann nephritis | Q80907742 | ||
Urinary heparanase activity in patients with Type 1 and Type 2 diabetes | Q83082153 | ||
P433 | issue | 21 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | acute kidney injury | Q424337 |
P304 | page(s) | 34191-34204 | |
P577 | publication date | 2017-05-01 | |
P1433 | published in | Oncotarget | Q1573155 |
P1476 | title | Involvement of heparanase in the pathogenesis of acute kidney injury: nephroprotective effect of PG545 | |
P478 | volume | 8 |
Q92925933 | Endothelial glycocalyx as a potential theriapeutic target in organ injuries |
Q59799492 | Inhibition of heparanase protects against chronic kidney dysfunction following ischemia/reperfusion injury |
Q64237303 | Ligustrazin increases lung cell autophagy and ameliorates paraquat-induced pulmonary fibrosis by inhibiting PI3K/Akt/mTOR and hedgehog signalling via increasing miR-193a expression |
Q47377873 | Opposing Functions of Heparanase-1 and Heparanase-2 in Cancer Progression |
Q89965719 | The Heparan Sulfate Mimetic PG545 Modulates T Cell Responses and Prevents Delayed-Type Hypersensitivity |
Q99712217 | The Yin and Yang of Alarmins in Regulation of Acute Kidney Injury |
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