Inhibition of heparanase protects against chronic kidney dysfunction following ischemia/reperfusion injury

Inhibition of heparanase protects against chronic kidney dysfunction following ischemia/reperfusion injury is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.26324
P932PMC publication ID6281411
P698PubMed publication ID30546836

P2093author name stringGianluigi Zaza
Antonio Lupo
Simona Granata
Valentina Masola
Giovanni Gambaro
Luigi Dall'Olmo
Maurizio Onisto
Gisella Vischini
Gloria Bellin
P2860cites workHospital Mortality in the United States following Acute Kidney InjuryQ26744765
Newly generated heparanase knock-out mice unravel co-regulation of heparanase and matrix metalloproteinasesQ28475274
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Heparanase and syndecan-1 interplay orchestrates fibroblast growth factor-2-induced epithelial-mesenchymal transition in renal tubular cellsQ35668839
Recent data concerning heparanase: focus on fibrosis, inflammation and cancerQ35836200
Heparanase Inhibition Reduces Glucose Levels, Blood Pressure, and Oxidative Stress in Apolipoprotein E Knockout MiceQ46068605
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Ischemia-Reperfusion Injury Reduces Long Term Renal Graft Survival: Mechanism and BeyondQ49340131
Heparanase regulates the M1 polarization of renal macrophages and their crosstalk with renal epithelial tubular cells after ischemia/reperfusion injury.Q50262560
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Phase I study of the heparanase inhibitor Roneparstat: an innovative approach for multiple myeloma therapy.Q52560290
Oxidative Stress and Renal Fibrosis: Recent Insights for the Development of Novel Therapeutic Strategies.Q52674866
Association between endothelin-1/endothelin receptor A and inflammation in mouse kidneys following acute ischemia/reperfusion.Q53649394
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Heparanase: A Potential New Factor Involved in the Renal Epithelial Mesenchymal Transition (EMT) Induced by Ischemia/Reperfusion (I/R) InjuryQ36088435
Endothelial Nitric Oxide Synthase Prevents Heparanase Induction and the Development of ProteinuriaQ36098881
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Heparanase promotes radiation resistance of cervical cancer by upregulating hypoxia inducible factor 1.Q37679989
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Acute kidney injury and chronic kidney disease as interconnected syndromesQ38225657
Molecular Dissection of Renal Ischemia-Reperfusion: Oxidative Stress and Cellular Events.Q38693936
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Specific heparanase inhibition reverses glucose-induced mesothelial-to-mesenchymal transition.Q39033979
The advancements of heparanase in fibrosisQ39080564
Ischemia/ReperfusionQ39109413
Heparanase: roles in cell survival, extracellular matrix remodelling and the development of kidney diseaseQ39120713
Epithelial to Mesenchymal Transition (EMT) and Endothelial to Mesenchymal Transition (EndMT): Role and Implications in Kidney FibrosisQ39242491
Dialysis-related transcriptomic profiling: the pivotal role of heparanaseQ39321185
Naturally Occurring Compounds: New Potential Weapons against Oxidative Stress in Chronic Kidney DiseaseQ39429579
Endothelin-1 Induces Proteinuria by Heparanase-Mediated Disruption of the Glomerular GlycocalyxQ39879255
Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established diseaseQ40666383
The role of oxygen free radicals in mediating the reperfusion injury of cold-preserved ischemic kidneysQ41487761
Involvement of heparanase in the pathogenesis of acute kidney injury: nephroprotective effect of PG545.Q41855773
The hemopexin domain of matrix metalloproteinase-9 activates cell signaling and promotes migration of schwann cells by binding to low-density lipoprotein receptor-related proteinQ41912504
Renal ischemia-reperfusion leads to long term infiltration of activated and effector-memory T lymphocytesQ41922589
Hypoxia Induces Mesenchymal Gene Expression in Renal Tubular Epithelial Cells: An in vitro Model of Kidney Transplant FibrosisQ43092586
Heparanase and macrophage interplay in the onset of liver fibrosisQ43812376
L-arginine deficiency and supplementation in experimental acute renal failure and in human kidney transplantationQ43936722
L-Arginine counteracts nitric oxide deficiency and improves the recovery phase of ischemic acute renal failure in ratsQ44465907
Identifying specific causes of kidney allograft loss.Q45810388
P433issue90
P407language of work or nameEnglishQ1860
P921main subjectreperfusion injuryQ1413991
P304page(s)36185-36201
P577publication date2018-11-16
P1433published inOncotargetQ1573155
P1476titleInhibition of heparanase protects against chronic kidney dysfunction following ischemia/reperfusion injury
P478volume9

Reverse relations

cites work (P2860)
Q90474075Kidney allograft fibrosis: what we learned from latest translational research studies
Q91798207Non-Anticoagulant Heparins as Heparanase Inhibitors

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