Long-term exposure to a high-fat diet results in the development of glucose intolerance and insulin resistance in interleukin-1 receptor I-deficient mice.

scientific article published on 6 August 2013

Long-term exposure to a high-fat diet results in the development of glucose intolerance and insulin resistance in interleukin-1 receptor I-deficient mice. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1152/AJPENDO.00297.2013
P932PMC publication ID3798700
P698PubMed publication ID23921145
P5875ResearchGate publication ID255694339

P50authorDomenico SergiQ37617313
Clare ReynoldsQ42797408
Kingston H MillsQ45449153
Helen M RocheQ56824883
Fiona C McGillicuddyQ61312559
Domenico SergiQ87210015
P2093author name stringLynda M Williams
Christine Grant
Karen A Harford
Eilish Coleman
Orla Finucane
P2860cites workInflammation and insulin resistanceQ22241893
Long-term treatment with interleukin-1beta induces insulin resistance in murine and human adipocytesQ24297968
The inflammasomesQ24304087
Inflammation and metabolic disordersQ27860923
Obesity is associated with macrophage accumulation in adipose tissueQ27860976
Oncogene-induced senescence relayed by an interleukin-dependent inflammatory networkQ27863386
IL-1 plays an important role in lipid metabolism by regulating insulin levels under physiological conditionsQ28506148
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesityQ28512778
Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulationQ28594238
Obesity induces a phenotypic switch in adipose tissue macrophage polarizationQ29547686
Thioredoxin-interacting protein links oxidative stress to inflammasome activationQ29614471
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystalsQ29615704
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signalingQ29616024
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistanceQ29616026
Protection from obesity-induced insulin resistance in mice lacking TNF-alpha functionQ29616104
CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesityQ29617380
TLR4 links innate immunity and fatty acid-induced insulin resistanceQ29617577
Fat tissue, aging, and cellular senescenceQ34130783
Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cellsQ34152594
Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in miceQ34178121
Impacts of transcriptional regulation on aging and senescenceQ34688038
Normalization of obesity-associated insulin resistance through immunotherapyQ34994222
Lack of interleukin-1 receptor I (IL-1RI) protects mice from high-fat diet-induced adipose tissue inflammation coincident with improved glucose homeostasis.Q35043422
The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivityQ36931760
Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animalsQ37072370
Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosisQ37073732
Selective versus total insulin resistance: a pathogenic paradoxQ37076798
Fats, inflammation and insulin resistance: insights to the role of macrophage and T-cell accumulation in adipose tissue.Q37915666
The cellular and signaling networks linking the immune system and metabolism in diseaseQ37991199
Inflammation and lipid signaling in the etiology of insulin resistanceQ38007632
Obesity in C57BL/6J mice is characterized by adipose tissue hypoxia and cytotoxic T-cell infiltration.Q38297857
Thermal and behavioral effects of lipopolysaccharide and influenza in interleukin-1 beta-deficient miceQ40678665
Dietary saturated fatty acids prime the NLRP3 inflammasome via TLR4 in dendritic cells-implications for diet-induced insulin resistance.Q42833764
Altered expression of C/EBP family members results in decreased adipogenesis with agingQ43608324
Interleukin-6-deficient mice develop mature-onset obesityQ43851625
C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat dietQ58106596
Increased Inflammatory Properties of Adipose Tissue Macrophages Recruited During Diet-Induced ObesityQ58197140
Is Interleukin-6 Receptor Blockade the Holy Grail for Inflammatory Diseases?Q59326168
Immune modulation: IL-1, master mediator or initiator of inflammationQ59632267
Age-Related Adipose Tissue mRNA Expression of ADD1/SREBP1, PPAR , Lipoprotein Lipase, and GLUT4 Glucose Transporter in Rhesus MonkeysQ60507133
Mature-Onset Obesity in Interleukin-1 Receptor I Knockout MiceQ61480334
Combined Interleukin-6 and Interleukin-1 Deficiency Causes Obesity in Young MiceQ62735763
T-lymphocyte infiltration in visceral adipose tissue: a primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistanceQ81108550
Lipotoxicity, an imbalance between lipogenesis de novo and fatty acid oxidationQ81127015
Decreased fat mass in interleukin-1 receptor antagonist-deficient mice: impact on adipogenesis, food intake, and energy expenditureQ81526916
Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistanceQ83864443
Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistanceQ84707922
P433issue7
P921main subjectinsulin resistanceQ1053470
glucose intoleranceQ2661464
P304page(s)E834-44
P577publication date2013-08-06
P1433published inAmerican Journal of Physiology - Endocrinology and MetabolismQ15765671
P1476titleLong-term exposure to a high-fat diet results in the development of glucose intolerance and insulin resistance in interleukin-1 receptor I-deficient mice
P478volume305