Final Report of the First Refractory Germ Cell Tumor Treated with Sunitinib Malate

scientific article published on 11 December 2009

Final Report of the First Refractory Germ Cell Tumor Treated with Sunitinib Malate is …
instance of (P31):
case reportQ2782326
scholarly articleQ13442814

External links are
P356DOI10.1159/000260901
P932PMC publication ID2914388
P698PubMed publication ID20737043
P5875ResearchGate publication ID45828264

P2093author name stringEnrique Grande Pulido
Joan Manel Gasent Blesa
Vicente Alberola Candel
Juan Laforga Canales
P2860cites workThe Hallmarks of CancerQ221226
Gonadal expression of c-kit encoded at the W locus of the mouseQ50803430
Angiogenetic protooncogene ets-1 induced neovascularization is involved in the metastatic process of testicular germ cell tumors.Q53376658
Expression of the mRNA for the ligand of c-kit in mouse Sertoli cellsQ67688860
Expression of vascular endothelial growth factor in patients with testicular germ cell tumors as an indicator of metastatic diseaseQ77214174
Stem cell factor receptor (c-KIT) codon 816 mutations predict development of bilateral testicular germ-cell tumorsQ79317172
Inhibition of tyrosine kinases PDGFR and C-Kit by imatinib mesylate interferes with postnatal testicular development in the ratQ80810852
The biology of VEGF and its receptorsQ27860704
The activated macrophage colony-stimulating factor (CSF-1) receptor as a predictor of poor outcome in advanced epithelial ovarian carcinomaQ31851169
Gemcitabine and oxaliplatin (GEMOX) in patients with cisplatin-refractory germ cell tumors: a phase II studyQ33359841
Kinase inhibitors in cancer therapy: a look aheadQ33897202
Role of tyrosine kinase inhibitors in cancer therapyQ34432091
Inhibition of KIT tyrosine kinase activity: a novel molecular approach to the treatment of KIT-positive malignanciesQ34564857
Regulation and targets of receptor tyrosine kinasesQ35045439
Flt3 receptor tyrosine kinase as a drug target in leukemiaQ35794059
The vascular endothelial growth factor family and its receptorsQ35913133
Sunitinib: from rational design to clinical efficacyQ36747062
Aberrant platelet-derived growth factor alpha-receptor transcript as a diagnostic marker for early human germ cell tumors of the adult testisQ37679463
Neovascularization in clinical stage A testicular germ cell tumor: prediction of metastatic disease.Q40388352
CSF-1 and its receptor in ovarian, endometrial and breast cancerQ40520354
RET tyrosine kinase and medullary thyroid cells are unaffected by clinical doses of STI571.Q40608959
Indolinone tyrosine kinase inhibitors block Kit activation and growth of small cell lung cancer cellsQ40809633
Neovascularization in human germ cell tumors correlates with a marked increase in the expression of the vascular endothelial growth factor but not the placenta-derived growth factor.Q41181353
Microvascular pericytes express platelet-derived growth factor-beta receptors in human healing wounds and colorectal adenocarcinoma.Q42050115
Differential expression of the c-kit proto-oncogene in germ cell tumours.Q42513650
SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivoQ44280921
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship.Q44285254
Alterations of the c-kit gene in testicular germ cell tumorsQ44490297
KIT and platelet-derived growth factor receptor alpha tyrosine kinase gene mutations and KIT amplifications in human solid tumorsQ45151889
The receptor tyrosine kinase inhibitor SU11248 impedes endothelial cell migration, tubule formation, and blood vessel formation in vivo, but has little effect on existing tumor vesselsQ45194202
Bevacizumab plus high-dose ifosfamide, etoposide and carboplatin (HD-ICE) as third-line salvage chemotherapy induced an unexpected dramatic response in highly platinum refractory germ-cell cancerQ46761398
P433issue3
P304page(s)234-241
P577publication date2009-12-11
P1433published inCase reports in oncologyQ27722654
P1476titleFinal Report of the First Refractory Germ Cell Tumor Treated with Sunitinib Malate
P478volume2

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cites work (P2860)
Q34544846Next generation sequencing analysis of platinum refractory advanced germ cell tumor sensitive to Sunitinib (Sutent®) a VEGFR2/PDGFRβ/c-kit/ FLT3/RET/CSF1R inhibitor in a phase II trial
Q38341798Testicular choriocarcinoma: a rare variant that requires a unique treatment approach

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