The receptor tyrosine kinase inhibitor SU11248 impedes endothelial cell migration, tubule formation, and blood vessel formation in vivo, but has little effect on existing tumor vessels

scientific article published in January 2004

The receptor tyrosine kinase inhibitor SU11248 impedes endothelial cell migration, tubule formation, and blood vessel formation in vivo, but has little effect on existing tumor vessels is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1008189263
P356DOI10.1007/S10456-004-3149-Y
P698PubMed publication ID15609077

P2093author name stringFei Ye
Yu Shyr
Dennis E Hallahan
Ling Geng
Allie Fu
Katherine L Osusky
P433issue3
P921main subjectendotheliumQ111140
P304page(s)225-233
P577publication date2004-01-01
P1433published inAngiogenesisQ15753544
P1476titleThe receptor tyrosine kinase inhibitor SU11248 impedes endothelial cell migration, tubule formation, and blood vessel formation in vivo, but has little effect on existing tumor vessels
P478volume7

Reverse relations

cites work (P2860)
Q34687036A phase Ib/II translational study of sunitinib with neoadjuvant radiotherapy in soft-tissue sarcoma
Q36335477Activation of alternate prosurvival pathways accounts for acquired sunitinib resistance in U87MG glioma xenografts
Q38869809An Unusual Case of Central Retinal Vein Occlusion and Review of the Toxicity Profile of Regorafenib in GIST Patients.
Q28543862An ex vivo model for anti-angiogenic drug testing on intact microvascular networks
Q36636633Anti-VEGF therapy: a new approach to colorectal cancer therapy
Q37230783Anti-angiogenic and vascular disrupting effects of C9, a new microtubule-depolymerizing agent
Q37955304Anti-angiogenic therapy: concept to clinic
Q33665288Antiangiogenetic Effects of 4 Varieties of Grapes In Vitro
Q37883011Antiangiogenic therapy, hypoxia, and metastasis: risky liaisons, or not?
Q38847330Assessment of tumor response to radiation and vascular targeting therapy in mice using quantitative ultrasound spectroscopy
Q37098098Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib
Q45934010Characteristic genotypes of vascular endothelial growth factor are susceptible to ascites in patients with cirrhosis.
Q54347154Circulating tumor-associated neutrophils (cTAN) contribute to circulating tumor cell survival by suppressing peripheral leukocyte activation.
Q36192000Clinical outcomes of patients with gastrointestinal stromal tumor in phase I clinical trials
Q39398836Combination of Temsirolimus and tyrosine kinase inhibitors in renal carcinoma and endothelial cell lines
Q36965629Combined sunitinib and radiation therapy for preoperative treatment of soft tissue sarcoma: results of a phase I trial of the German interdisciplinary sarcoma group (GISG-03).
Q35597086Consequence of dose scheduling of sunitinib on host immune response elements and vaccine combination therapy
Q36625228Current and future therapeutic approaches for metastatic pheochromocytoma and paraganglioma: focus on SDHB tumors
Q37578218Development of sunitinib in hepatocellular carcinoma: rationale, early clinical experience, and correlative studies
Q36611473Digestive tract hemorrhage due to complications with gastrointestinal stromal tumor treated with sunitinib: A case report
Q44760028Dose-dependent response of tumor vasculature to radiation therapy in combination with Sunitinib depicted by three-dimensional high-frequency power Doppler ultrasound
Q37357314Early development of sunitinib in hepatocellular carcinoma
Q34645665Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo-controlled, phase 3 trial
Q28268831Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial
Q34656707Efficacy of sorafenib in patients with gastrointestinal stromal tumors in the third- or fourth-line treatment: A retrospective multicenter experience.
Q41885351Final Report of the First Refractory Germ Cell Tumor Treated with Sunitinib Malate
Q47673133Gastrointestinal Malignancy: Genetic Implications to Clinical Applications
Q37218711Heterogeneity of kinase inhibitor resistance mechanisms in GIST
Q59430751Hypertension in cancer patients treated with anti-angiogenic based regimens
Q35634179Immune consequences of tyrosine kinase inhibitors that synergize with cancer immunotherapy
Q37847051Immunomodulatory effects of anti-angiogenic drugs
Q49592831Immunotherapeutic Targeting of Tumor-Associated Blood Vessels
Q37576843Impact of rechallenge with imatinib in patients with advanced gastrointestinal stromal tumor after failure of imatinib and sunitinib.
Q33384849Improved bone healing by angiogenic factor-enriched platelet-rich plasma and its synergistic enhancement by bone morphogenetic protein-2
Q33738607In vivo spectral and fluorescence microscopy comparison of microvascular function after treatment with OXi4503, Sunitinib and their combination in Caki-2 tumors
Q33552232Indolyl-quinuclidinols inhibit ENOX activity and endothelial cell morphogenesis while enhancing radiation-mediated control of tumor vasculature
Q39880781Inhibition of cell proliferation, vascular endothelial growth factor and tumor growth by albendazole
Q37673218Inostamycin prevents malignant phenotype of cancer: inhibition of phosphatidylinositol synthesis provides a therapeutic advantage for head and neck squamous cell carcinoma
Q37799829Latest developments in targeted therapy for hepatocellular carcinoma.
Q36906667Molecular basis for sunitinib efficacy and future clinical development
Q36293536Molecular research directions in the management of gastrointestinal stromal tumors
Q38389986Multi-targeted tyrosine kinase inhibitors for the treatment of non-small cell lung cancer: an era of individualized therapy
Q41554303One-day treatment of small molecule 8-bromo-cyclic AMP analogue induces cell-based VEGF production for in vitro angiogenesis and osteoblastic differentiation
Q34226634PRKX, TTBK2 and RSK4 expression causes Sunitinib resistance in kidney carcinoma- and melanoma-cell lines
Q38099390Pharmacokinetics and pharmacodynamics of sunitinib for the treatment of advanced pancreatic neuroendocrine tumors
Q37190323Phase I trial of concurrent sunitinib and radiation therapy as preoperative treatment for soft tissue sarcoma
Q38176966Regorafenib for treatment of advanced gastrointestinal stromal tumors.
Q35519994Regorafenib treatment for advanced, refractory gastrointestinal stromal tumor: a report of the UK managed access program
Q91979492Relationship between efficacy of sunitinib and KIT mutation of patients with advanced gastrointestinal stromal tumors after failure of imatinib: A systematic review
Q37254387Risk of hypertension and renal dysfunction with an angiogenesis inhibitor sunitinib: systematic review and meta-analysis
Q46957688Sunitinib
Q37301234Sunitinib (SUTENT) for the treatment of metastatic renal cell carcinoma
Q37797460Sunitinib for Metastatic Renal Cell Carcinoma
Q34884647Sunitinib for Taiwanese patients with gastrointestinal stromal tumor after imatinib treatment failure or intolerance
Q37960905Sunitinib for advanced pancreatic neuroendocrine tumors.
Q37307562Sunitinib for advanced renal cell cancer
Q35871185Sunitinib for patients with locally advanced or distantly metastatic dermatofibrosarcoma protuberans but resistant to imatinib
Q39952447Sunitinib in advanced pancreatic neuroendocrine tumors: latest evidence and clinical potential
Q28072057Sunitinib in the treatment of metastatic renal cell carcinoma
Q34380617Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells
Q37226817Sunitinib prolongs survival in genetically engineered mouse models of multistep lung carcinogenesis
Q36858232Sunitinib, a multitargeted tyrosine kinase inhibitor, in the management of gastrointestinal stromal tumor
Q39889569Sunitinib-induced cardiotoxicity is mediated by off-target inhibition of AMP-activated protein kinase
Q54353589Sunitinib: from charge-density studies to interaction with proteins.
Q44500706Sunitinib: in advanced, well differentiated pancreatic neuroendocrine tumors
Q28066499Sunitinib: the antiangiogenic effects and beyond
Q37905587Targeted therapy in renal cancer
Q33920350Targeting the vasculature in hepatocellular carcinoma treatment: Starving versus normalizing blood supply.
Q91789075The Use of Molecular Subtypes for Precision Therapy of Recurrent and Metastatic Gastrointestinal Stromal Tumor
Q38144166The potential of sunitinib as a therapy in ovarian cancer
Q37521316The role of antiangiogenesis therapy: bevacizumab and beyond
Q35975387The tipping point for combination therapy: cancer vaccines with radiation, chemotherapy, or targeted small molecule inhibitors
Q48634468The use of sunitinib in renal cell carcinoma: where are we now?
Q54559288Two cases of bowel perforation associated with sunitinib treatment for renal cell carcinoma.
Q38874224VEGFR2-Targeted Contrast-Enhanced Ultrasound to Distinguish between Two Anti-Angiogenic Treatments.
Q54548367[Current status and future direction of multi-targeted drugs in the era of personalized therapy--overview of advances in multi-targeted therapy in non-small cell lung cancer].