Variations in ATM protein expression during normal lymphoid differentiation and among B-cell-derived neoplasias (scientific article published on August 2003)

ATM Mutations and Phenotypes in Ataxia-Telangiectasia Families in the British Isles: Expression of Mutant ATM and the Risk of Leukemia, Lymphoma, and Breast Cancer

Q34384444

A gene transcribed from the bidirectional ATM promoter coding for a serine rich protein: amino acid sequence, structure and expression studies

Q34407801

Sensing of intermediates in V(D)J recombination by ATM.

Q35005088

Mantle cell lymphoma is characterized by inactivation of the ATM gene

Q35081325

The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage

Q36023721

Immature thymocytes undergoing receptor rearrangements are resistant to an Atm-dependent death pathway activated in mature T cells by double-stranded DNA breaks

Q36368896

Upregulation of ATM in sclerosing adenosis of the breast

Q37641353

Epidermal growth factor sensitizes cells to ionizing radiation by down-regulating protein mutated in ataxia-telangiectasia.

Q38306307

DNA-PK, the DNA-activated protein kinase, is differentially expressed in normal and malignant human tissues

Q38324394

Biallelic mutations in the ATM gene in T-prolymphocytic leukemia

Q38342470

Clustering of missense mutations in the ataxia-telanglectasia gene in a sporadic T-cell leukaemia

Q38343194

ATM mutations are associated with inactivation of the ARF-TP53 tumor suppressor pathway in diffuse large B-cell lymphoma

Q38363906

The controlling role of ATM in homologous recombinational repair of DNA damage

Q40386992

Residual ataxia telangiectasia mutated protein function in cells from ataxia telangiectasia patients, with 5762ins137 and 7271T-->G mutations, showing a less severe phenotype.

Q40802404

Ionizing radiation activates the ATM kinase throughout the cell cycle

Q40893193

ATM is upregulated during the mitogenic response in peripheral blood mononuclear cells.

Q40930503

Leukemia and lymphoma in ataxia telangiectasia

Q40941950

Inactivation of the ATM gene in T-cell prolymphocytic leukemias

Q41032963

Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms

Q41115236

Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart

Q41689524

Expression pattern of the Nijmegen breakage syndrome gene, Nbs1, during murine development

Q41924510

Analysis of the ATM protein in wild-type and ataxia telangiectasia cells

Q42806067

Visualization of focal nuclear sites of DNA repair synthesis induced by bleomycin in human cells

Q43735945

ATM gene inactivation in mantle cell lymphoma mainly occurs by truncating mutations and missense mutations involving the phosphatidylinositol-3 kinase domain and is associated with increasing numbers of chromosomal imbalances

Q43833429

Expression status of BCL-6 and syndecan-1 identifies distinct histogenetic subtypes of Hodgkin's disease

Q43962210

ATM mutations in B-cell chronic lymphocytic leukemia.

Q47993904

V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors

Q52200236

Ataxia telangiectasia mutated-deficient B-cell chronic lymphocytic leukemia occurs in pregerminal center cells and results in defective damage response and unrepaired chromosome damage

Q63384027

p53 dysfunction in B-cell chronic lymphocytic leukemia: inactivation of ATM as an alternative to TP53 mutation

Q63384029

Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia

Q63384032

Somatic ATM mutations indicate a pathogenic role of ATM in B-cell chronic lymphocytic leukemia

Q77974880

P433

issue

P407

language of work or name

English

Q1860

P304

page(s)

423-432

P577

publication date

2003-08-01

P1433

published in

The American Journal of Pathology

Q4744259

P1476

title

Variations in ATM protein expression during normal lymphoid differentiation and among B-cell-derived neoplasias

P478

volume

163

Reverse relations

cites work (P2860)

Q36179581	Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase.
Q42541714	Checkpoint kinase 2 is required for efficient immunoglobulin diversification
Q52340211	Chromosomal Instability in Hodgkin Lymphoma: An In-Depth Review and Perspectives
Q34090009	Do mantle cell lymphomas have an 'Achilles heel'?
Q38298223	Down-regulation of ATM protein in HRS cells of nodular sclerosis Hodgkin's lymphoma in children occurs in the absence of ATM gene inactivation.
Q27851412	Genetic and molecular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics
Q35553338	MicroRNA profiles of t(14;18)-negative follicular lymphoma support a late germinal center B-cell phenotype
Q36909318	Non-conservative homologous recombination in human B lymphocytes is promoted by activation-induced cytidine deaminase and transcription.
Q44176325	Pathogenic ATM mutations occur rarely in a subset of multiple myeloma patients.
Q36089253	RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling
Q41475620	Roles of DNA Damage Response Proteins in Mitogen-Induced Thp-1 Differentiation into Macrophage
Q57279493	Single-cell analysis of loss of heterozygosity at theATM gene locus in Hodgkin and Reed-Sternberg cells of Hodgkin's lymphoma:ATM loss of heterozygosity is a rare event
Q38357428	The ATM tumour suppressor gene is down-regulated in EBV-associated nasopharyngeal carcinoma.
Q24317783	The Potential Role of BRCA1-Associated ATM Activator-1 (BRAT1) in Regulation of mTOR
Q24304499	The ataxia-oculomotor apraxia 1 gene product has a role distinct from ATM and interacts with the DNA strand break repair proteins XRCC1 and XRCC4
Q35966216	Translational initiation regulated by ATM in dendritic cells development