| scholarly article | Q13442814 |
| review article | Q7318358 |
| P2093 | author name string | Bernd Jahrsdörfer | |
| Magdalena Hagn | |||
| P2860 | cites work | Antiangiogenic plasma activity in patients with systemic sclerosis | Q81377099 |
| Human B cells differentiate into granzyme B-secreting cytotoxic B lymphocytes upon incomplete T-cell help | Q84639319 | ||
| Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function | Q24290522 | ||
| A quarter century of granzymes | Q24613762 | ||
| Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes | Q24675937 | ||
| The major human and mouse granzymes are structurally and functionally divergent | Q24682724 | ||
| Perforin-independent expression of granzyme B and proteinase inhibitor 9 in human testis and placenta suggests a role for granzyme B-mediated proteolysis in reproduction | Q28207297 | ||
| Extracellular granzymes A and B in humans: detection of native species during CTL responses in vitro and in vivo | Q28266759 | ||
| Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins | Q28266921 | ||
| Interleukin-21: Basic Biology and Implications for Cancer and Autoimmunity | Q29042353 | ||
| How regulatory T cells work | Q29614262 | ||
| Granzyme B produced by human plasmacytoid dendritic cells suppresses T-cell expansion. | Q30496008 | ||
| Cell surface-bound heat shock protein 70 (Hsp70) mediates perforin-independent apoptosis by specific binding and uptake of granzyme B. | Q30967103 | ||
| Granzyme B proteolyzes receptors important to proliferation and survival, tipping the balance toward apoptosis | Q33247896 | ||
| Tumor-infiltrating T cells correlate with NY-ESO-1-specific autoantibodies in ovarian cancer | Q33377058 | ||
| Granules of cytolytic T-lymphocytes contain two serine esterases | Q33880013 | ||
| Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin | Q33960986 | ||
| Subtractive hybridization reveals the expression of immunoglobulin-like transcript 7, Eph-B1, granzyme B, and 3 novel transcripts in human plasmacytoid dendritic cells | Q34154814 | ||
| Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism | Q34392100 | ||
| Extracellular matrix remodeling by human granzyme B via cleavage of vitronectin, fibronectin, and laminin. | Q34412822 | ||
| Apoptosis induced by the lymphocyte effector molecule perforin | Q34653908 | ||
| A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses | Q34778834 | ||
| Naturally occurring B-cell responses to breast cancer | Q35200581 | ||
| Granzyme B regulates antiviral CD8+ T cell responses | Q35613097 | ||
| Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection. | Q35765491 | ||
| Identification and characterization of circulating human transitional B cells | Q35847513 | ||
| Dysfunctional B cells in systemic lupus erythematosus | Q35952042 | ||
| Viral proteins targeting mitochondria: controlling cell death | Q35970213 | ||
| Human and murine granzyme B exhibit divergent substrate preferences | Q36117776 | ||
| Apoptotic pathways are selectively activated by granzyme A and/or granzyme B in CTL-mediated target cell lysis | Q36322609 | ||
| B-cell cross-presentation of autologous antigen precipitates diabetes. | Q36339548 | ||
| Antigen presentation by hapten-specific B lymphocytes. I. Role of surface immunoglobulin receptors | Q36349536 | ||
| A case for regulatory B cells | Q36360842 | ||
| Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation. | Q36368577 | ||
| Cleavage by granzyme B is strongly predictive of autoantigen status: implications for initiation of autoimmunity | Q36375304 | ||
| Role of B-1a cells in autoimmunity | Q36557386 | ||
| IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells. | Q51986478 | ||
| NK- and B-cell infiltration correlates with worse outcome in metastatic ovarian carcinoma. | Q53257187 | ||
| Mouse and human granzyme B have distinct tetrapeptide specificities and abilities to recruit the bid pathway. | Q53581862 | ||
| Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells. | Q54515149 | ||
| Perforin-dependent apoptosis functionally compensates Fas deficiency in activation-induced cell death of human T lymphocytes | Q57014792 | ||
| Activated Mouse B Cells Lack Expression of Granzyme B | Q57272555 | ||
| Antihemostatic Activity of Human Granzyme B Mediated by Cleavage of von Willebrand Factor | Q58023226 | ||
| Antigen-specific interaction between T and B cells | Q59063745 | ||
| New Paradigm for Lymphocyte Granule-mediated Cytotoxicity | Q59156993 | ||
| New paradigm for lymphocyte granule-mediated cytotoxicity. Target cells bind and internalize granzyme B, but an endosomolytic agent is necessary for cytosolic delivery and subsequent apoptosis | Q64382665 | ||
| Mechanism of adenovirus-mediated endosome lysis: role of the intact adenovirus capsid structure | Q64383361 | ||
| Mouse T-cell associated serine proteinase 1 degrades collagen type IV: a structural basis for the migration of lymphocytes through vascular basement membranes | Q70178454 | ||
| Human lymphocytes making rheumatoid factor and antibody to ssDNA belong to Leu-1+ B-cell subset | Q70333975 | ||
| Acquisition of granzyme B and Fas ligand proteins by human keratinocytes contributes to epidermal cell defense | Q74456557 | ||
| Granzyme B, a novel mediator of allergic inflammation: its induction and release in blood basophils and human asthma | Q79775036 | ||
| Granzyme B is critical for T cell receptor-induced cell death of type 2 helper T cells | Q80092770 | ||
| Human mast cells produce and release the cytotoxic lymphocyte associated protease granzyme B upon activation | Q80279457 | ||
| Extracellular granzymes: current perspectives | Q36567777 | ||
| Expression of endogenous granzyme B in a subset of human primary breast carcinomas | Q36670835 | ||
| Interleukin 21: a cytokine/cytokine receptor system that has come of age | Q36803809 | ||
| The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancer | Q36897846 | ||
| The development and function of regulatory B cells expressing IL-10 (B10 cells) requires antigen receptor diversity and TLR signals | Q37069155 | ||
| Non-apoptotic functions of granzymes | Q37106664 | ||
| Sepsis alters the megakaryocyte-platelet transcriptional axis resulting in granzyme B-mediated lymphotoxicity. | Q37126477 | ||
| The role of IL-21 in regulating B-cell function in health and disease. | Q37211251 | ||
| Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I. | Q37225614 | ||
| Regulatory B cells as inhibitors of immune responses and inflammation | Q37256986 | ||
| Interleukin 21 as a target of intervention in autoimmune disease | Q37331107 | ||
| The battlefield of perforin/granzyme cell death pathways. | Q37633282 | ||
| Suppressive functions of activated B cells in autoimmune diseases reveal the dual roles of Toll-like receptors in immunity. | Q37700798 | ||
| Non-cytotoxic antiviral activities of granzymes in the context of the immune antiviral state. | Q37763996 | ||
| CD20+ B cells: the other tumor-infiltrating lymphocytes | Q37801779 | ||
| Normal, autoimmune, and malignant CD5+ B cells: the Ly-1 B lineage? | Q39647319 | ||
| Monocyte derived dendritic cells generated by IFN-alpha acquire mature dendritic and natural killer cell properties as shown by gene expression analysis | Q39755645 | ||
| Granzyme B is expressed in urothelial carcinoma and promotes cancer cell invasion. | Q39760255 | ||
| Human and mouse granzyme A induce a proinflammatory cytokine response. | Q39925412 | ||
| Macrophages express granzyme B in the lesion areas of atherosclerosis and rheumatoid arthritis | Q40112834 | ||
| TCR activation eliminates glutamate receptor GluR3 from the cell surface of normal human T cells, via an autocrine/paracrine granzyme B-mediated proteolytic cleavage. | Q40187335 | ||
| Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity | Q40323654 | ||
| A novel dendritic cell subset involved in tumor immunosurveillance | Q40323661 | ||
| Granzyme B induces smooth muscle cell apoptosis in the absence of perforin: involvement of extracellular matrix degradation | Q40506485 | ||
| Killing of target cells by redirected granzyme B in the absence of perforin | Q40573776 | ||
| Caspase activation by granzyme B is indirect, and caspase autoprocessing requires the release of proapoptotic mitochondrial factors. | Q40662424 | ||
| Granzyme B and perforin lytic proteins are expressed in CD34+ peripheral blood progenitor cells mobilized by chemotherapy and granulocyte colony-stimulating factor | Q41278655 | ||
| Granzyme B-dependent proteolysis acts as a switch to enhance the proinflammatory activity of IL-1α. | Q42185747 | ||
| B-chronic lymphocytic leukemia cells and other B cells can produce granzyme B and gain cytotoxic potential after interleukin-21-based activation. | Q42742024 | ||
| A natural killer cell granule protein that induces DNA fragmentation and apoptosis | Q42768665 | ||
| IFN-α enhances cross-presentation in human dendritic cells by modulating antigen survival, endocytic routing, and processing. | Q43047480 | ||
| Noncytotoxic lytic granule-mediated CD8+ T cell inhibition of HSV-1 reactivation from neuronal latency | Q43130211 | ||
| Human B cells secrete granzyme B when recognizing viral antigens in the context of the acute phase cytokine IL-21. | Q43517682 | ||
| Granule-associated serine proteases: granzymes might not just be killer proteases | Q43974512 | ||
| The granzyme B gene is highly polymorphic in wild mice but essentially invariant in common inbred laboratory strains. | Q43985343 | ||
| Granzyme B-mediated degradation of T-cell receptor zeta chain. | Q44123678 | ||
| Expression of granzyme B in human articular chondrocytes. | Q44546192 | ||
| Granzyme B and perforin: constitutive expression in human polymorphonuclear neutrophils | Q44598253 | ||
| Granzyme B leakage-induced cell death: a new type of activation-induced natural killer cell death. | Q44667094 | ||
| Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells | Q44967317 | ||
| CD5+ B cells from individuals with systemic lupus erythematosus express granzyme B. | Q45176452 | ||
| Interleukin-21 mRNA expression during virus infections | Q45420919 | ||
| Granzyme B, a new player in activation-induced cell death, is down-regulated by vasoactive intestinal peptide in Th2 but not Th1 effectors | Q46859572 | ||
| Distinct activation signals determine whether IL-21 induces B cell costimulation, growth arrest, or Bim-dependent apoptosis | Q47309544 | ||
| Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis. | Q47781476 | ||
| P433 | issue | 8 | |
| P921 | main subject | cell differentiation | Q210861 |
| P304 | page(s) | 1368-1375 | |
| P577 | publication date | 2012-11-01 | |
| P1433 | published in | OncoImmunology | Q18026500 |
| P1476 | title | Why do human B cells secrete granzyme B? Insights into a novel B-cell differentiation pathway | |
| P478 | volume | 1 |
| Q35161548 | A colorimetric assay that specifically measures Granzyme B proteolytic activity: hydrolysis of Boc-Ala-Ala-Asp-S-Bzl |
| Q47881002 | Age-Associated B Cells with Proinflammatory Characteristics Are Expanded in a Proportion of Multiple Sclerosis Patients. |
| Q27314611 | Bovine Leukemia Virus Small Noncoding RNAs Are Functional Elements That Regulate Replication and Contribute to Oncogenesis In Vivo |
| Q41854631 | CD27(+)IgD(-) B cells in the peripheral blood of colorectal cancer patients: on anti-tumor or tumor-protective mission? |
| Q40484859 | Cytotoxic Epstein-Barr virus-positive large B cell lymphoma: a regulatory B cell-derived neoplasia? |
| Q90708034 | Double-edge Role of B Cells in Tumor Immunity: Potential Molecular Mechanism |
| Q37719216 | Elevated granzyme B+ B-cell level in SIV-infection correlate with viral load and low CD4 T-cell count |
| Q90167137 | Granzyme B Attenuates Bacterial Virulence by Targeting Secreted Factors |
| Q92018196 | High expression of granzyme B in conventional CD4+ T cells is associated with increased relapses after allogeneic stem cells transplantation in patients with hematological malignancies |
| Q36538934 | Increased IL-21 Expression Induces Granzyme B in Peripheral CD5(+) B Cells as a Potential Counter-Regulatory Effect in Primary Sjögren's Syndrome |
| Q38201655 | Manipulation of tumour-infiltrating B cells and tertiary lymphoid structures: a novel anti-cancer treatment avenue? |
| Q40743794 | Norovirus antagonism of B-cell antigen presentation results in impaired control of acute infection |
| Q28080994 | Reconsidering the detection of tolerance to individualize immunosuppression minimization and to improve long-term kidney graft outcomes |
| Q99711533 | Regulatory B Cells and Its Role in Central Nervous System Inflammatory Demyelinating Diseases |
| Q38957186 | Regulatory B Cells with a Partial Defect in CD40 Signaling and Overexpressing Granzyme B Transfer Allograft Tolerance in Rodents. |
| Q37420774 | Regulatory B cells and tolerance in transplantation: from animal models to human. |
| Q94569843 | Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma |
| Q28078919 | The Biological Effects of IL-21 Signaling on B-Cell-Mediated Responses in Organ Transplantation |
| Q36104784 | Tolerant Kidney Transplant Patients Produce B Cells with Regulatory Properties |
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