An RpoB Mutation Confers Dual Heteroresistance to Daptomycin and Vancomycin in Staphylococcus aureus

scientific article published on September 13, 2010

An RpoB Mutation Confers Dual Heteroresistance to Daptomycin and Vancomycin in Staphylococcus aureus is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/AAC.00437-10
P953full work available at URLhttp://intl-aac.asm.org/cgi/content/abstract/54/12/5222
https://aac.asm.org/content/54/12/5222.full.pdf
https://doi.org/10.1128/aac.00437-10
https://europepmc.org/articles/PMC2981288
https://europepmc.org/articles/PMC2981288?pdf=render
https://journals.asm.org/doi/pdf/10.1128/AAC.00437-10
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20837752/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20837752/pdf/?tool=EBI
P932PMC publication ID2981288
P698PubMed publication ID20837752

P50authorHui-Min NeohQ56451773
Ilana L. CamargoQ79142007
Keiichi HiramatsuQ106083013
P2093author name stringMinoru Fukuda
Yukiko Watanabe
Tomonori Ochiai
Tomomi Hishinuma
Longzhu Cui
Mitsutaka Shoji
Taisuke Isii
P2860cites workStudies on the mechanism of ristocetin-induced platelet agglutination. Effects of structural modification of ristocetin and vancomycinQ24595238
Lipid-specific binding of the calcium-dependent antibiotic daptomycin leads to changes in lipid polymorphism of model membranes.Q31155851
Differential effect of rpoB mutations on antibacterial activities of rifampicin and KRM-1648 against Staphylococcus aureusQ31830904
DNA microarray-based identification of genes associated with glycopeptide resistance in Staphylococcus aureus.Q33220466
Effect of divalent cations on the structure of the antibiotic daptomycin.Q46925250
Daptomycin: a novel agent for Gram-positive infections.Q53852746
Vancomycin adsorption to Bacillus subtilis cell wallsQ69982951
Overexpression of sigma factor, sigma(B), urges Staphylococcus aureus to thicken the cell wall and to resist beta-lactamsQ74630591
Development of decreased susceptibility to daptomycin and vancomycin in a Staphylococcus aureus strain during prolonged therapyQ79922013
How bacteraemia is reviewed by medicines licensing authorities in EuropeQ81330455
The GraRS regulatory system controls Staphylococcus aureus susceptibility to antimicrobial host defenses.Q33339694
Inactivation of the dlt operon in Staphylococcus aureus confers sensitivity to defensins, protegrins, and other antimicrobial peptidesQ33855582
Bactericidal activities of two daptomycin regimens against clinical strains of glycopeptide intermediate-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and methicillin-resistant Staphylococcus aureus isolates in an in viQ33981366
Cell wall thickening is not a universal accompaniment of the daptomycin nonsusceptibility phenotype in Staphylococcus aureus: evidence for multiple resistance mechanismsQ34045376
Development of Daptomycin resistance in vivo in methicillin-resistant Staphylococcus aureusQ34073487
The emergence and evolution of methicillin-resistant Staphylococcus aureusQ34094813
Status of methods for assessing bacterial cell surface charge properties based on zeta potential measurementsQ34105427
In vitro activity of novel rifamycins against rifamycin-resistant Staphylococcus aureusQ34509698
Vancomycin-resistant Staphylococcus aureus: a new model of antibiotic resistanceQ34547868
Tracking the in vivo evolution of multidrug resistance in Staphylococcus aureus by whole-genome sequencingQ34630593
Genetic changes that correlate with reduced susceptibility to daptomycin in Staphylococcus aureusQ34680589
Cell wall thickening is a common feature of vancomycin resistance in Staphylococcus aureusQ34747322
Evolution of a vancomycin-intermediate Staphylococcus aureus strain in vivo: multiple changes in the antibiotic resistance phenotypes of a single lineage of methicillin-resistant S. aureus under the impact of antibiotics administered for chemotherapQ34975155
Suppression of methicillin resistance in a mecA-containing pre-methicillin-resistant Staphylococcus aureus strain is caused by the mecI-mediated repression of PBP 2' productionQ35129607
Correlation of daptomycin bactericidal activity and membrane depolarization in Staphylococcus aureusQ35166213
Staphylococcus aureus with reduced susceptibility to vancomycinQ35882353
Characterization of a daptomycin-nonsusceptible vancomycin-intermediate Staphylococcus aureus strain in a patient with endocarditis.Q36094925
Failures in clinical treatment of Staphylococcus aureus Infection with daptomycin are associated with alterations in surface charge, membrane phospholipid asymmetry, and drug bindingQ36422686
Daptomycin: a review 4 years after first approvalQ36972980
NMR structural studies of the antibiotic lipopeptide daptomycin in DHPC micelles.Q36975076
Serial daptomycin selection generates daptomycin-nonsusceptible Staphylococcus aureus strains with a heterogeneous vancomycin-intermediate phenotype.Q38360418
Contribution of a thickened cell wall and its glutamine nonamidated component to the vancomycin resistance expressed by Staphylococcus aureus Mu50.Q39474811
RNA polymerase inhibitors with activity against rifampin-resistant mutants of Staphylococcus aureusQ39537295
Characterization of mutations in the rpoB gene that confer rifampin resistance in Staphylococcus aureusQ39559116
Molecular genetic and structural modeling studies of Staphylococcus aureus RNA polymerase and the fitness of rifampin resistance genotypes in relation to clinical prevalenceQ41851810
Genetic analysis of factors affecting susceptibility of Bacillus subtilis to daptomycinQ41884192
Mutated response regulator graR is responsible for phenotypic conversion of Staphylococcus aureus from heterogeneous vancomycin-intermediate resistance to vancomycin-intermediate resistance.Q41912284
Induction of daptomycin heterogeneous susceptibility in Staphylococcus aureus by exposure to vancomycinQ42042890
Selection of heterogeneous vancomycin-intermediate Staphylococcus aureus by imipenemQ42111612
Analysis of cell membrane characteristics of in vitro-selected daptomycin-resistant strains of methicillin-resistant Staphylococcus aureusQ42111665
Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus.Q42111733
Correlation between Reduced Daptomycin Susceptibility and Vancomycin Resistance in Vancomycin-Intermediate Staphylococcus aureus.Q42112490
Novel mechanism of antibiotic resistance originating in vancomycin-intermediate Staphylococcus aureus.Q42112516
Interaction of the GraRS two-component system with the VraFG ABC transporter to support vancomycin-intermediate resistance in Staphylococcus aureusQ42119436
daptomycin activity against Staphylococcus aureus following vancomycin exposure in an in vitro pharmacodynamic model with simulated endocardial vegetationsQ42197385
Staphylococcus aureus strains lacking D-alanine modifications of teichoic acids are highly susceptible to human neutrophil killing and are virulence attenuated in mice.Q44074411
Resistance to a polyquaternium-1 lens care solution and isoelectric points of Pseudomonas aeruginosa strainsQ44080445
Daptomycin.Q44751135
Identification of the first vancomycin intermediate-resistant Staphylococcus aureus (VISA) isolate from a hospital in PortugalQ44837920
Allelic replacement in Staphylococcus aureus with inducible counter-selection.Q46624193
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectStaphylococcus aureusQ188121
vancomycinQ424027
P304page(s)5222-5233
P577publication date2010-09-13
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleAn RpoB mutation confers dual heteroresistance to daptomycin and vancomycin in Staphylococcus aureus
An RpoB Mutation Confers Dual Heteroresistance to Daptomycin and Vancomycin in Staphylococcus aureus
P478volume54

Reverse relations

cites work (P2860)
Q42109713"Slow VISA," a novel phenotype of vancomycin resistance, found in vitro in heterogeneous vancomycin-intermediate Staphylococcus aureus strain Mu3.
Q30455758A mutation in the PP2C phosphatase gene in a Staphylococcus aureus USA300 clinical isolate with reduced susceptibility to vancomycin and daptomycin
Q90502080A mutation in the glycosyltransferase gene lafB causes daptomycin hypersusceptibility in Enterococcus faecium
Q36505583A mutation of the RNA polymerase β' subunit (rpoC) confers cephalosporin resistance in Bacillus subtilis.
Q34648042Additional routes to Staphylococcus aureus daptomycin resistance as revealed by comparative genome sequencing, transcriptional profiling, and phenotypic studies
Q40631566Antibiotic Combinations with Daptomycin for Treatment of Staphylococcus aureus Infections
Q38310639Antimicrobial heteroresistance: an emerging field in need of clarity.
Q100395098Association of mprF mutations with cross-resistance to daptomycin and vancomycin in methicillin-resistant Staphylococcus aureus (MRSA)
Q99630758Characterization of methicillin-resistant Staphylococcus aureus through genomics approach
Q38394500Collateral sensitivity of antibiotic-resistant microbes.
Q36964857Comparative proteomics-based identification of genes associated with glycopeptide resistance in clinically derived heterogeneous vancomycin-intermediate Staphylococcus aureus strains
Q40719288Complete Reconstitution of the Vancomycin-Intermediate Staphylococcus aureus Phenotype of Strain Mu50 in Vancomycin-Susceptible S. aureus
Q59647553Comprehensive antibiotic-linked mutation assessment by resistance mutation sequencing (RM-seq)
Q37335734Comprehensive identification of mutations responsible for heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA)-to-VISA conversion in laboratory-generated VISA strains derived from hVISA clinical strain Mu3
Q48505745Convergent Evolution Driven by Rifampin Exacerbates the Global Burden of Drug-Resistant Staphylococcus aureus.
Q36056622Coordinated phenotype switching with large-scale chromosome flip-flop inversion observed in bacteria
Q30575519Current data and trends on methicillin-resistant Staphylococcus aureus (MRSA)
Q26863225Cyclic lipodepsipeptides: a new class of antibacterial agents in the battle against resistant bacteria
Q47616115Daptomycin
Q58609304Daptomycin Resistance and Tolerance Due to Loss of Function in Staphylococcus aureus dsp1 and asp23.
Q47116570Daptomycin Resistance in Clinical MRSA Strains Is Associated with a High Biological Fitness Cost
Q34405922Daptomycin resistance in enterococci is associated with distinct alterations of cell membrane phospholipid content
Q33696380Dissecting vancomycin-intermediate resistance in staphylococcus aureus using genome-wide association.
Q37824612Emergence of daptomycin resistance following vancomycin-unresponsive Staphylococcus aureus bacteraemia in a daptomycin-naïve patient--a review of the literature
Q92091420Environment Shapes the Accessible Daptomycin Resistance Mechanisms in Enterococcus faecium
Q33939055Evaluation of Daptomycin Non-Susceptible Staphylococcus aureus for Stability, Population Profiles, mprF Mutations, and Daptomycin Activity
Q40602795Evaluation of telavancin activity versus daptomycin and vancomycin against daptomycin-nonsusceptible Staphylococcus aureus in an in vitro pharmacokinetic/pharmacodynamic model
Q41570351Evaluation of the novel combination of high-dose daptomycin plus trimethoprim-sulfamethoxazole against daptomycin-nonsusceptible methicillin-resistant Staphylococcus aureus using an in vitro pharmacokinetic/pharmacodynamic model of simulated endocar
Q28477900Evolution of multidrug resistance during Staphylococcus aureus infection involves mutation of the essential two component regulator WalKR
Q90165730Evolution of resistance mechanisms and biological characteristics of rifampicin-resistant Staphylococcus aureus strains selected in vitro
Q24490083Evolution of resistance to a last-resort antibiotic in Staphylococcus aureus via bacterial competition
Q34116509First case report of vancomycin-intermediate sequence type 72 Staphylococcus aureus with nonsusceptibility to daptomycin
Q44704078First isolation in Argentina of community-acquired methicillin-resistant Staphylococcus aureus with intermediate susceptibility to vancomycin and nonsusceptibility to daptomycin
Q42202739Generation of a vancomycin-intermediate Staphylococcus aureus (VISA) strain by two amino acid exchanges in VraS.
Q34389310Genetic and proteomic characterization of rpoB mutations and their effect on nematicidal activity in Photorhabdus luminescens LN2.
Q33876255Genetic basis for daptomycin resistance in enterococci
Q37643403Genome sequence-based discriminator for vancomycin-intermediate Staphylococcus aureus.
Q42738785Genome-wide analysis captures the determinants of the antibiotic cross-resistance interaction network.
Q58716354Genomic exploration of sequential clinical isolates reveals a distinctive molecular signature of persistent Staphylococcus aureus bacteraemia
Q57823035Global spread of three multidrug-resistant lineages of Staphylococcus epidermidis
Q35385568Heterogeneity of genetic pathways toward daptomycin nonsusceptibility in Staphylococcus aureus determined by adjunctive antibiotics
Q35807220Heteroresistance to cephalosporins and penicillins in Acinetobacter baumannii
Q41855274Impact of rpoB mutations on reduced vancomycin susceptibility in Staphylococcus aureus
Q36999966Improved understanding of factors driving methicillin-resistant Staphylococcus aureus epidemic waves
Q40056214In vivo development of daptomycin resistance in vancomycin-susceptible methicillin-resistant Staphylococcus aureus severe infections previously treated with glycopeptides.
Q41862843In vivo evolution of antimicrobial resistance in a series of Staphylococcus aureus patient isolates: the entire picture or a cautionary tale?
Q37658042Large tandem chromosome expansions facilitate niche adaptation during persistent infection with drug-resistant Staphylococcus aureus
Q37947249MRSA: the first half century
Q33613003Management of Resistant, Atypical and Culture-negative Periprosthetic Joint Infections after Hip and Knee Arthroplasty
Q38942573Mechanism of Action and Resistance to Daptomycin in Staphylococcus aureus and Enterococci
Q38380412Molecular analysis of methicillin-resistant Staphylococcus aureus dissemination among healthcare professionals and/or HIV patients from a tertiary hospital.
Q34536929Molecular characterization of methicillin-resistant Panton-valentine leukocidin positive staphylococcus aureus clones disseminating in Tunisian hospitals and in the community
Q59806009Molecular prophage typing of isolates from bovine mastitis
Q28480626Multiple mutations in heterogeneous miltefosine-resistant Leishmania major population as determined by whole genome sequencing
Q38282740Mutation of RNA polymerase beta subunit (rpoB) promotes hVISA-to-VISA phenotypic conversion of strain Mu3.
Q42110109Mutation of RNA polymerase β-subunit gene promotes heterogeneous-to-homogeneous conversion of β-lactam resistance in methicillin-resistant Staphylococcus aureus
Q34593241Mutations in the primary sigma factor σA and termination factor rho that reduce susceptibility to cell wall antibiotics
Q35867495Mutations in the β subunit of RNA polymerase alter intrinsic cephalosporin resistance in Enterococci
Q40809099Phenotypic Modifications in Staphylococcus aureus Cells Exposed to High Concentrations of Vancomycin and Teicoplanin
Q38966881Potential for adaptation overrides cost of resistance.
Q34632683Production of capsular polysaccharide does not influence Staphylococcus aureus vancomycin susceptibility
Q89500845RNA polymerase mutations cause cephalosporin resistance in clinical Neisseria gonorrhoeae isolates
Q59805017Reconstruction of the Vancomycin-Susceptible Phenotype From a Vancomycin-Intermediate XN108
Q38282693Reduction in membrane phosphatidylglycerol content leads to daptomycin resistance in Bacillus subtilis
Q41129709Research of the heteroresistance of Pseudomonas aeruginosa to imipenem.
Q35619094Resistance to "last resort" antibiotics in Gram-positive cocci: The post-vancomycin era
Q42772389Reversible daptomycin tolerance of adherent staphylococci in an implant infection model
Q36081351Rifampin Resistance rpoB Alleles or Multicopy Thioredoxin/Thioredoxin Reductase Suppresses the Lethality of Disruption of the Global Stress Regulator spx in Staphylococcus aureus
Q36153912Serine/threonine phosphatase Stp1 contributes to reduced susceptibility to vancomycin and virulence in Staphylococcus aureus
Q35746096Staphylococcus aureus metabolic adaptations during the transition from a daptomycin susceptibility phenotype to a daptomycin nonsusceptibility phenotype.
Q36158472Stepwise decrease in daptomycin susceptibility in clinical Staphylococcus aureus isolates associated with an initial mutation in rpoB and a compensatory inactivation of the clpX gene
Q37683485The impact of drug resistance on Mycobacterium tuberculosis physiology: what can we learn from rifampicin?
Q34436348Transposon library screening for identification of genetic loci participating in intrinsic susceptibility and acquired resistance to antistaphylococcal agents.
Q39392178Use of bacterial whole-genome sequencing to understand and improve the management of invasive Staphylococcus aureus infections
Q92490264Using genomics to understand meticillin- and vancomycin-resistant Staphylococcus aureus infections
Q95355781Vancomycin Resistance in Staphylococcus aureus
Q38462842Vancomycin in the treatment of methicillin-resistant Staphylococcus aureus - a clinician's guide to the science informing current practice
Q37236231Vancomycin susceptibility in methicillin-resistant Staphylococcus aureus is mediated by YycHI activation of the WalRK essential two-component regulatory system
Q57492422as a Prominent Resource of Future Anti-MRSA Drugs
Q42110968walK and clpP mutations confer reduced vancomycin susceptibility in Staphylococcus aureus.

Search more.