A mutation in the PP2C phosphatase gene in a Staphylococcus aureus USA300 clinical isolate with reduced susceptibility to vancomycin and daptomycin

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A mutation in the PP2C phosphatase gene in a Staphylococcus aureus USA300 clinical isolate with reduced susceptibility to vancomycin and daptomycin is …
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scholarly articleQ13442814

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P356DOI10.1128/AAC.05770-11
P932PMC publication ID3457403
P698PubMed publication ID22850507
P5875ResearchGate publication ID230591911

P50authorKarla D PassalacquaQ41671776
P2093author name stringTimothy D Read
Emily K Crispell
Sarah W Satola
P2860cites workRegulation of hemolysin expression and virulence of Staphylococcus aureus by a serine/threonine kinase and phosphataseQ21136345
The COG database: an updated version includes eukaryotesQ21284294
Community-associated methicillin-resistant Staphylococcus aureus: epidemiology and clinical consequences of an emerging epidemicQ24614464
The skin microbiomeQ24634180
Reduced vancomycin susceptibility in Staphylococcus aureus, including vancomycin-intermediate and heterogeneous vancomycin-intermediate strains: resistance mechanisms, laboratory detection, and clinical implicationsQ24646677
Rapid and simple comparison of messenger RNA levels using real-time PCR.Q25257674
Solution structure of the parvulin-type PPIase domain of Staphylococcus aureus PrsA – Implications for the catalytic mechanism of parvulinsQ27654271
Crystal Structure of Staphylococcus aureus Metallopeptidase (Sapep) Reveals Large Domain Motions between the Manganese-bound and Apo-statesQ27663269
A genomic perspective on protein familiesQ27860913
Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureusQ28300379
Interplay in the selection of fluoroquinolone resistance and bacterial fitnessQ28475870
Whole genome sequencing and complete genetic analysis reveals novel pathways to glycopeptide resistance in Staphylococcus aureusQ28478770
An alternate conformation and a third metal in PstP/Ppp, the M. tuberculosis PP2C-Family Ser/Thr protein phosphataseQ28486667
Bacterial community variation in human body habitats across space and timeQ29547432
Fast algorithms for large-scale genome alignment and comparisonQ29618357
Multilocus sequence typing for characterization of methicillin-resistant and methicillin-susceptible clones of Staphylococcus aureusQ29619365
Staphylococcus aureus expresses a cell surface protein that binds both IgG and beta2-glycoprotein I.Q30671163
A second IgG-binding protein in Staphylococcus aureusQ32064577
Treatment failure resulting from resistance of Staphylococcus aureus to daptomycinQ33233009
Exploring glycopeptide-resistance in Staphylococcus aureus: a combined proteomics and transcriptomics approach for the identification of resistance-related markers.Q33264418
Subtle genetic changes enhance virulence of methicillin resistant and sensitive Staphylococcus aureusQ33305151
Different bacterial gene expression patterns and attenuated host immune responses are associated with the evolution of low-level vancomycin resistance during persistent methicillin-resistant Staphylococcus aureus bacteraemiaQ33321447
Detection and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates in Canada: results from the Canadian Nosocomial Infection Surveillance Program, 1995-2006.Q33613735
Methicillin-resistant Staphylococcus aureus endocarditis and de novo development of daptomycin resistance during therapyQ42656550
Structure and complexity of a bacterial transcriptome.Q42841193
Penicillin-binding protein folding is dependent on the PrsA peptidyl-prolyl cis-trans isomerase in Bacillus subtilisQ43058422
Extended spectrum of quinolone resistance, even to a potential latter third-generation agent, as a result of a minimum of two GrlA and two GyrA alterations in quinolone-resistant Staphylococcus aureusQ43091444
Vancomycin MIC plus heteroresistance and outcome of methicillin-resistant Staphylococcus aureus bacteremia: trends over 11 yearsQ43117809
Treatment outcomes for serious infections caused by methicillin-resistant Staphylococcus aureus with reduced vancomycin susceptibilityQ43433837
Biological cost and compensatory evolution in fusidic acid-resistant Staphylococcus aureusQ43579575
Effects of environment on compensatory mutations to ameliorate costs of antibiotic resistanceQ44144059
Impact of USA300 methicillin-resistant Staphylococcus aureus on clinical outcomes of patients with pneumonia or central line-associated bloodstream infectionsQ44422021
Identification of the first vancomycin intermediate-resistant Staphylococcus aureus (VISA) isolate from a hospital in PortugalQ44837920
Nucleotide substitutions in Staphylococcus aureus strains, Mu50, Mu3, and N315.Q44894963
Occurrence of a USA300 vancomycin-intermediate Staphylococcus aureusQ46325792
Comparative proteomics analyses reveal a potential biomarker for the detection of vancomycin-intermediate Staphylococcus aureus strainsQ46903914
Structure-function analysis of PrsA reveals roles for the parvulin-like and flanking N- and C-terminal domains in protein folding and secretion in Bacillus subtilis.Q51026793
Staphylococcal coagulase; mode of action and antigenicity.Q51043511
Role of insertion elements and yycFG in the development of decreased susceptibility to vancomycin in Staphylococcus aureus.Q51580715
Methicillin-resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibility.Q55067143
Enhanced in vivo fitness of fluoroquinolone-resistant Campylobacter jejuni in the absence of antibiotic selection pressureQ33756688
Staphylococcus aureus deficient in lipidation of prelipoproteins is attenuated in growth and immune activationQ33769293
The Staphylococcus aureus RNome and its commitment to virulenceQ33851489
Waves of resistance: Staphylococcus aureus in the antibiotic era.Q33854398
A spectrum of changes occurs in peptidoglycan composition of glycopeptide-intermediate clinical Staphylococcus aureus isolatesQ33981239
Accessory gene regulator (agr) locus in geographically diverse Staphylococcus aureus isolates with reduced susceptibility to vancomycinQ34107062
Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children: executive summaryQ34158152
Complete nucleotide sequence analysis of plasmids in strains of Staphylococcus aureus clone USA300 reveals a high level of identity among isolates with closely related core genome sequencesQ34433256
Tracking the in vivo evolution of multidrug resistance in Staphylococcus aureus by whole-genome sequencingQ34630593
Emergence of multidrug-resistant, community-associated, methicillin-resistant Staphylococcus aureus clone USA300 in men who have sex with men.Q34751827
Role of the accessory gene regulator agr in community-associated methicillin-resistant Staphylococcus aureus pathogenesis.Q34931778
Host defenses against Staphylococcus aureus infection require recognition of bacterial lipoproteinsQ35025079
Heterogeneous vancomycin-intermediate susceptibility in a community-associated methicillin-resistant Staphylococcus aureus epidemic clone, in a case of Infective Endocarditis in ArgentinaQ35035275
The Sbi protein is a multifunctional immune evasion factor of Staphylococcus aureusQ35191984
Post-translocational folding of secretory proteins in Gram-positive bacteriaQ35951996
The posttranslocational chaperone lipoprotein PrsA is involved in both glycopeptide and oxacillin resistance in Staphylococcus aureusQ36086420
Relationship between vancomycin MIC and failure among patients with methicillin-resistant Staphylococcus aureus bacteremia treated with vancomycinQ36870858
Modulation of cell wall structure and antimicrobial susceptibility by a Staphylococcus aureus eukaryote-like serine/threonine kinase and phosphataseQ37144963
The first vancomycin-intermediate Staphylococcus aureus strains isolated from patients in ThailandQ37256413
Susceptibility relationship between vancomycin and daptomycin in Staphylococcus aureus: facts and assumptionsQ37602845
The impact of serine/threonine phosphorylation in Staphylococcus aureusQ37604056
Antibiotic resistance and its cost: is it possible to reverse resistance?Q37704177
Emergence of daptomycin resistance following vancomycin-unresponsive Staphylococcus aureus bacteraemia in a daptomycin-naïve patient--a review of the literatureQ37824612
Eukaryote-like serine/threonine kinases and phosphatases in bacteriaQ37849482
Cell wall composition and decreased autolytic activity and lysostaphin susceptibility of glycopeptide-intermediate Staphylococcus aureusQ40166227
Fitness cost of VanA-type vancomycin resistance in methicillin-resistant Staphylococcus aureusQ41840194
Emergence of a clinical daptomycin-resistant Staphylococcus aureus isolate during treatment of methicillin-resistant Staphylococcus aureus bacteremia and osteomyelitisQ41847174
Impact of rpoB mutations on reduced vancomycin susceptibility in Staphylococcus aureusQ41855274
An RpoB Mutation Confers Dual Heteroresistance to Daptomycin and Vancomycin in Staphylococcus aureusQ41902616
Mutated response regulator graR is responsible for phenotypic conversion of Staphylococcus aureus from heterogeneous vancomycin-intermediate resistance to vancomycin-intermediate resistance.Q41912284
Differential target gene activation by the Staphylococcus aureus two-component system saeRS.Q41989725
walK and clpP mutations confer reduced vancomycin susceptibility in Staphylococcus aureus.Q42110968
Genetic determinants of resistance to fusidic acid among clinical bacteremia isolates of Staphylococcus aureusQ42111680
Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus.Q42111733
Correlation between Reduced Daptomycin Susceptibility and Vancomycin Resistance in Vancomycin-Intermediate Staphylococcus aureus.Q42112490
Interaction of the GraRS two-component system with the VraFG ABC transporter to support vancomycin-intermediate resistance in Staphylococcus aureusQ42119436
Failure of Vancomycin Continuous Infusion against Experimental Endocarditis Due to Vancomycin-Intermediate Staphylococcus aureusQ42147280
Comparison of detection methods for heteroresistant vancomycin-intermediate Staphylococcus aureus, with the population analysis profile method as the reference methodQ42169334
The protein phosphatase 2C (PP2C) superfamily: detection of bacterial homologues.Q42247167
spa typing for epidemiological surveillance of Staphylococcus aureusQ42624365
P4510describes a project that usesImageJQ1659584
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectRNA sequencingQ2542347
Staphylococcus aureusQ188121
vancomycinQ424027
P1104number of pages12
P304page(s)5212-5223
P577publication date2012-07-30
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleA mutation in the PP2C phosphatase gene in a Staphylococcus aureus USA300 clinical isolate with reduced susceptibility to vancomycin and daptomycin
P478volume56