Constitutive activation of STAT5A and STAT5B regulates IgM secretion in Waldenstrom's macroglobulinemia

scientific article published on 11 December 2013

Constitutive activation of STAT5A and STAT5B regulates IgM secretion in Waldenstrom's macroglobulinemia is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1182/BLOOD-2013-08-521963
P932PMC publication ID3924927
P698PubMed publication ID24335105
P5875ResearchGate publication ID259320063

P2093author name stringAnne J Novak
Stephen M Ansell
Lucy S Hodge
Zhi-Zhang Yang
Steven C Ziesmer
Frank J Secreto
P2860cites workConstitutive STAT5 activation specifically cooperates with the loss of p53 function in B-cell lymphomagenesis.Q46987226
Constitutive activation of Stat5 promotes its cytoplasmic localization and association with PI3-kinase in myeloid leukemiasQ58029666
Loss of signal transducer and activator of transcription 5 leads to hepatosteatosis and impaired liver regenerationQ80638835
Phosphorylated STAT5 represents a new possible prognostic marker in Hodgkin lymphomaQ80732588
STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cellsQ24534351
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteinsQ27860890
Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responsesQ28592023
Signal transducer and activator of transcription 5b, c-Src, and epidermal growth factor receptor signaling play integral roles in estrogen-stimulated proliferation of estrogen receptor-positive breast cancer cellsQ30439082
Discovery of chromone-based inhibitors of the transcription factor STAT5.Q33318036
Mutational switch of an IL-6 response to an interferon-gamma-like responseQ34031049
Stat5a/b are essential for normal lymphoid development and differentiationQ34253065
STAT5 and Oct-1 form a stable complex that modulates cyclin D1 expression.Q34985773
Ebf1 or Pax5 haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemiaQ35213566
Comprehensive analysis of tumor microenvironment cytokines in Waldenstrom macroglobulinemia identifies CCL5 as a novel modulator of IL-6 activityQ35553334
Differential function of STAT5 isoforms in head and neck cancer growth controlQ38289837
Constitutive activation of the JAK2/STAT5 signal transduction pathway correlates with growth factor independence of megakaryocytic leukemic cell linesQ38326792
Constitutive activation of Stat5b contributes to carcinogenesis in vivoQ38348600
IL-21 in the bone marrow microenvironment contributes to IgM secretion and proliferation of malignant cells in Waldenstrom macroglobulinemiaQ39278952
Novel indoloquinoline derivative, IQDMA, inhibits STAT5 signaling associated with apoptosis in K562 cellsQ46181906
P433issue7
P407language of work or nameEnglishQ1860
P1104number of pages4
P304page(s)1055-1058
P577publication date2013-12-11
P1433published inBloodQ885070
P1476titleConstitutive activation of STAT5A and STAT5B regulates IgM secretion in Waldenstrom's macroglobulinemia
P478volume123

Reverse relations

cites work (P2860)
Q40858735Comprehensive genomic profiling of IgM multiple myeloma identifies IRF4 as a prognostic marker.
Q27021855Factors regulating immunoglobulin production by normal and disease-associated plasma cells
Q38723769Histone H1 and Chromosomal Protein HMGN2 Regulate Prolactin-induced STAT5 Transcription Factor Recruitment and Function in Breast Cancer Cells
Q38542260Ibrutinib for the treatment of Waldenström macroglobulinemia
Q28546079Methotrexate Is a JAK/STAT Pathway Inhibitor
Q53087536Phospho-flow detection of constitutive and cytokine-induced pSTAT3/5, pAKT and pERK expression highlights novel prognostic biomarkers for patients with multiple myeloma.

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