Neural stem and progenitor cells shorten S-phase on commitment to neuron production

scientific article published on January 2011

Neural stem and progenitor cells shorten S-phase on commitment to neuron production is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2011NatCo...2..154A
P356DOI10.1038/NCOMMS1155
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/ncomms1155
P932PMC publication ID3105305
P698PubMed publication ID21224845
P5875ResearchGate publication ID49745675

P50authorFederico CalegariQ56742079
Wieland B HuttnerQ88117952
P2093author name stringChristiane Haffner
Yoko Arai
Jeremy N Pulvers
Britta Schilling
Ina Nüsslein
P2860cites workAutomated analysis of time-lapse fluorescence microscopy images: from live cell images to intracellular foci.Q50574048
Expression of proliferating cell nuclear antigen (PCNA) in the adult and developing mouse nervous system.Q52166894
Bromodeoxyuridine immunohistochemical determination of the lengths of the cell cycle and the DNA-synthetic phase for an anatomically defined population.Q52530993
The cell cycle of the pseudostratified ventricular epithelium of the embryonic murine cerebral wallQ64117434
Early ontogeny of the secondary proliferative population of the embryonic murine cerebral wallQ72037992
G1 phase regulation, area-specific cell cycle control, and cytoarchitectonics in the primate cortexQ35839746
Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesisQ36229183
Symmetric versus asymmetric cell division during neurogenesis in the developing vertebrate central nervous systemQ36294221
Chromatin remodeling in DNA replication.Q36347528
Fanconi DNA repair pathway is required for survival and long-term maintenance of neural progenitorsQ36492462
Role of intermediate progenitor cells in cerebral cortex developmentQ37030395
Distinct behaviors of neural stem and progenitor cells underlie cortical neurogenesisQ37082090
Concise review: Pax6 transcription factor contributes to both embryonic and adult neurogenesis as a multifunctional regulatorQ37158287
Making bigger brains-the evolution of neural-progenitor-cell division.Q37248292
The cell biology of neural stem and progenitor cells and its significance for their proliferation versus differentiation during mammalian brain developmentQ37302457
Cell cycle control of mammalian neural stem cells: putting a speed limit on G1.Q37691982
Epigenetic control of neural precursor cell fate during developmentQ37756526
Neural progenitor nuclei IN motionQ37792379
Cortical progenitor expansion, self-renewal and neurogenesis-a polarized perspectiveQ37805233
Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genesQ40016836
Maximal chromosome compaction occurs by axial shortening in anaphase and depends on Aurora kinaseQ40122169
Numbers, time and neocortical neuronogenesis: a general developmental and evolutionary modelQ40372315
Existence of two populations of cyclin/proliferating cell nuclear antigen during the cell cycle: association with DNA replication sitesQ41526470
Brca1 is required for embryonic development of the mouse cerebral cortex to normal size by preventing apoptosis of early neural progenitorsQ42452985
Cdk4/cyclinD1 overexpression in neural stem cells shortens G1, delays neurogenesis, and promotes the generation and expansion of basal progenitors.Q42459454
Pax6 controls radial glia differentiation in the cerebral cortexQ42465397
An inhibition of cyclin-dependent kinases that lengthens, but does not arrest, neuroepithelial cell cycle induces premature neurogenesisQ44660997
Asymmetric production of surface-dividing and non-surface-dividing cortical progenitor cellsQ47401361
Cellular roles of dna topoisomerases: a molecular perspectiveQ22121990
Cyclin G1 and cyclin G2 comprise a new family of cyclins with contrasting tissue-specific and cell cycle-regulated expressionQ24309263
The glial nature of embryonic and adult neural stem cellsQ24602498
Neurons arise in the basal neuroepithelium of the early mammalian telencephalon: a major site of neurogenesisQ24624356
Expression of the antiproliferative gene TIS21 at the onset of neurogenesis identifies single neuroepithelial cells that switch from proliferative to neuron-generating divisionQ24670425
E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpointsQ24672780
Live imaging at the onset of cortical neurogenesis reveals differential appearance of the neuronal phenotype in apical versus basal progenitor progenyQ27301092
The gene PC3(TIS21/BTG2), prototype member of the PC3/BTG/TOB family: regulator in control of cell growth, differentiation, and DNA repair?Q28206741
Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phasesQ28236938
Selective lengthening of the cell cycle in the neurogenic subpopulation of neural progenitor cells during mouse brain developmentQ28261372
The cell biology of neurogenesisQ28284165
The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zoneQ28507289
Targeted inactivation of p12, CDK2 associating protein 1, leads to early embryonic lethalityQ28512766
Selective utilization of nonhomologous end-joining and homologous recombination DNA repair pathways during nervous system developmentQ28585656
The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesisQ28590512
Tbr2 directs conversion of radial glia into basal precursors and guides neuronal amplification by indirect neurogenesis in the developing neocortexQ28593799
Patterns of neural stem and progenitor cell division may underlie evolutionary cortical expansionQ29616186
Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortexQ29616194
Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensationQ29617905
G1 events and regulation of cell proliferationQ29618317
Intermediate neuronal progenitors (basal progenitors) produce pyramidal-projection neurons for all layers of cerebral cortexQ30490142
Forced G1-phase reduction alters mode of division, neuron number, and laminar phenotype in the cerebral cortex.Q30492178
Glial cells generate neurons: the role of the transcription factor Pax6.Q34118701
Dynamics of DNA replication factories in living cellsQ34508274
Cell-cycle control and cortical developmentQ34630030
Differential repression of c-myc and cdc2 gene expression by ERF and PE-1/METS.Q34631603
The RAS-dependent ERF control of cell proliferation and differentiation is mediated by c-Myc repressionQ34663276
Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms.Q34989521
Radial glia diversity: a matter of cell fateQ35133543
Cdc25A phosphatase: combinatorial phosphorylation, ubiquitylation and proteolysisQ35691551
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivs 3.0 UnportedQ19125045
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P407language of work or nameEnglishQ1860
P304page(s)154
P577publication date2011-01-01
P1433published inNature CommunicationsQ573880
P1476titleNeural stem and progenitor cells shorten S-phase on commitment to neuron production
P478volume2

Reverse relations

cites work (P2860)
Q618138413,4,5-Tricaffeoylquinic acid induces adult neurogenesis and improves deficit of learning and memory in aging model senescence-accelerated prone 8 mice
Q30661673A Branching Process to Characterize the Dynamics of Stem Cell Differentiation
Q90106842A multiscale mathematical model of cell dynamics during neurogenesis in the mouse cerebral cortex
Q48769574A new approach to manipulate the fate of single neural stem cells in tissue.
Q36740841A systemic transcriptome analysis reveals the regulation of neural stem cell maintenance by an E2F1-miRNA feedback loop
Q98718301A transient role of the ciliary gene Inpp5e in controlling direct versus indirect neurogenesis in cortical development
Q38750052ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules.
Q41103145ASPM regulates symmetric stem cell division by tuning Cyclin E ubiquitination
Q52724659Ablation of cdk4 and cdk6 affects proliferation of basal progenitor cells in the developing dorsal and ventral forebrain.
Q35667564Abundant occurrence of basal radial glia in the subventricular zone of embryonic neocortex of a lissencephalic primate, the common marmoset Callithrix jacchus.
Q30541639Amplification of progenitors in the mammalian telencephalon includes a new radial glial cell type.
Q28652020An adaptive threshold in mammalian neocortical evolution
Q42125676Analysis of neural progenitors from embryogenesis to juvenile adult in Xenopus laevis reveals biphasic neurogenesis and continuous lengthening of the cell cycle
Q27318211Aneuploidy causes premature differentiation of neural and intestinal stem cells
Q41194140Antenatal dexamethasone exposure differentially affects distinct cortical neural progenitor cells and triggers long-term changes in murine cerebral architecture and behavior
Q38038637Apicobasal polarity and cell proliferation during development
Q64097780Asymmetric division events promote variability in cell cycle duration in animal cells and Escherichia coli
Q38212357Asymmetric inheritance of Cyclin D2 maintains proliferative neural stem/progenitor cells: a critical event in brain development and evolution
Q42260123Bioelectric state and cell cycle control of Mammalian neural stem cells
Q49993554BrdU/EdU dual labeling to determine the cell-cycle dynamics of defined cellular subpopulations.
Q48372802Brief report: Adult hippocampal precursor cells shorten S-phase and total cell cycle length during neuronal differentiation.
Q42275132CRISPR-mediated genomic deletion of Sox2 in the axolotl shows a requirement in spinal cord neural stem cell amplification during tail regeneration.
Q38699787CRISPR/Cas9-induced disruption of gene expression in mouse embryonic brain and single neural stem cells in vivo.
Q96229704CYCLIN-B1/2 and -D1 act in opposition to coordinate cortical progenitor self-renewal and lineage commitment
Q38272073Can the 'neuron theory' be complemented by a universal mechanism for generic neuronal differentiation
Q49031975Caspr Controls the Temporal Specification of Neural Progenitor Cells through Notch Signaling in the Developing Mouse Cerebral Cortex.
Q35116856Cell biological regulation of division fate in vertebrate neuroepithelial cells
Q27011457Cell cycle activity of neural precursors in the diseased mammalian brain
Q38254753Cell cycle and cell fate in the developing nervous system: the role of CDC25B phosphatase.
Q48257032Cerebellar granule cells are predominantly generated by terminal symmetric divisions of granule cell precursors.
Q28596452Coevolution of radial glial cells and the cerebral cortex
Q34137540Comparative analysis of the subventricular zone in rat, ferret and macaque: evidence for an outer subventricular zone in rodents
Q37546242Concise Review: Control of Cell Fate Through Cell Cycle and Pluripotency Networks
Q28690751Conical expansion of the outer subventricular zone and the role of neocortical folding in evolution and development
Q46308537Coupling progenitor and neuronal diversity in the developing neocortex.
Q42345385Cyclin G2 promotes cell cycle arrest in breast cancer cells responding to fulvestrant and metformin and correlates with patient survival.
Q54996669DGCR8 Promotes Neural Progenitor Expansion and Represses Neurogenesis in the Mouse Embryonic Neocortex.
Q40773653DYRK1A-mediated Cyclin D1 Degradation in Neural Stem Cells Contributes to the Neurogenic Cortical Defects in Down Syndrome
Q90047387Defective DNA Polymerase α-Primase Leads to X-Linked Intellectual Disability Associated with Severe Growth Retardation, Microcephaly, and Hypogonadism
Q91222697Developmental changes in interkinetic nuclear migration dynamics with respect to cell-cycle progression in the mouse cerebral cortex ventricular zone
Q28973606Differences and similarities between human and chimpanzee neural progenitors during cerebral cortex development
Q53021494Different neural crest populations exhibit diverse proliferative behaviors.
Q30539951Direct visualization of cell division using high-resolution imaging of M-phase of the cell cycle
Q37685924Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly
Q64092737Divide or Commit - Revisiting the Role of Cell Cycle Regulators in Adult Hippocampal Neurogenesis
Q91329903Dynamics of cortical progenitors and production of subcerebral neurons are altered in embryos of a maternal inflammation model for autism
Q36803962Effects of addictive drugs on adult neural stem/progenitor cells.
Q38017628Emerging roles of neural stem cells in cerebral cortex development and evolution.
Q38691234Encoding and decoding time in neural development
Q42498876Enhanced Abventricular Proliferation Compensates Cell Death in the Embryonic Cerebral Cortex.
Q55512165Evidence for neurogenesis in the medial cortex of the leopard gecko, Eublepharis macularius
Q89367594Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels
Q90455014Extracellular matrix-inducing Sox9 promotes both basal progenitor proliferation and gliogenesis in developing neocortex
Q38726550Formula G1: Cell cycle in the driver's seat of stem cell fate determination.
Q50426412From proliferation to target innervation: signaling molecules that direct sympathetic nervous system development.
Q49158436Geminin regulates cortical progenitor proliferation and differentiation.
Q34098187Gene expression profiling of embryonic human neural stem cells and dopaminergic neurons from adult human substantia nigra
Q48850164Germinal zones in the developing cerebral cortex of ferret: ontogeny, cell cycle kinetics, and diversity of progenitors.
Q58733466Gli3 controls the onset of cortical neurogenesis by regulating the radial glial cell cycle through expression
Q33588405Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons
Q36546951Hes4 controls proliferative properties of neural stem cells during retinal ontogenesis
Q48660323Homeostatic neurogenesis in the adult hippocampus does not involve amplification of Ascl1(high) intermediate progenitors.
Q38359785How the cell cycle impacts chromatin architecture and influences cell fate
Q41865122How to keep proliferative neural stem/progenitor cells: a critical role of asymmetric inheritance of cyclin D2
Q43194378Human-chimpanzee differences in a FZD8 enhancer alter cell-cycle dynamics in the developing neocortex
Q24320258Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
Q60931384Human-specific induces hallmarks of neocortical expansion in developing ferret neocortex
Q37188543Impaired Memory in OT-II Transgenic Mice Is Associated with Decreased Adult Hippocampal Neurogenesis Possibly Induced by Alteration in Th2 Cytokine Levels
Q35228912In utero gene therapy rescues microcephaly caused by Pqbp1-hypofunction in neural stem progenitor cells
Q28729120In vivo importance of homologous recombination DNA repair for mouse neural stem and progenitor cells
Q35861867Intermediate progenitors are increased by lengthening of the cell cycle through calcium signaling and p53 expression in human neural progenitors
Q47851474Lack of Methyl-CpG Binding Protein 2 (MeCP2) Affects Cell Fate Refinement During Embryonic Cortical Development
Q36044003Lack of a p21waf1/cip -dependent G1/S checkpoint in neural stem and progenitor cells after DNA damage in vivo.
Q36393229Lateral cortical Cdca7 expression levels are regulated by Pax6 and influence the production of intermediate progenitors
Q52723140Lgr5+ intestinal stem cells reside in an unlicensed G1 phase.
Q36120417Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis
Q38593733Linking the Cell Cycle to Cell Fate Decisions
Q42505393Loss of Cdk2 and Cdk4 induces a switch from proliferation to differentiation in neural stem cells.
Q28655884Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology
Q28506694MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway
Q33957193Maintaining genome stability in the nervous system
Q50793409Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons.
Q39890685Mapping neurogenesis onset in the optic tectum of Xenopus laevis
Q45764369Maternal Sevoflurane Exposure Causes Abnormal Development of Fetal Prefrontal Cortex and Induces Cognitive Dysfunction in Offspring.
Q37644511Meningeal retinoic acid contributes to neocortical lamination and radial migration during mouse brain development
Q41949639MicroRNA 22 regulates cell cycle length in cerebellar granular neuron precursors.
Q35156816Microinjection of membrane-impermeable molecules into single neural stem cells in brain tissue
Q64093709Modular Total Synthesis and Cell-Based Anticancer Activity Evaluation of Ouabagenin and Other Cardiotonic Steroids with Varying Degrees of Oxygenation
Q100316248N,N-dimethyltryptamine compound found in the hallucinogenic tea ayahuasca, regulates adult neurogenesis in vitro and in vivo
Q48239456N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications.
Q38208906Nervous decision-making: to divide or differentiate
Q36580299Neural development is dependent on the function of specificity protein 2 in cell cycle progression
Q38793343Neural progenitor cells and their role in the development and evolutionary expansion of the neocortex
Q38196796Neurogenesis during development of the vertebrate central nervous system
Q37060311Neurogenesis in the Developing and Adult Brain-Similarities and Key Differences
Q41826040Neurogenesis requires TopBP1 to prevent catastrophic replicative DNA damage in early progenitors.
Q56812374Neurogenic decisions require a cell cycle independent function of the CDC25B phosphatase
Q41899163Neurogenin2-d4Venus and Gadd45g-d4Venus transgenic mice: visualizing mitotic and migratory behaviors of cells committed to the neuronal lineage in the developing mammalian brain
Q36126063Neuronal specification exploits the inherent flexibility of cell-cycle gap phases
Q26781874New Horizons in Enhancing the Proliferation and Differentiation of Neural Stem Cells Using Stimulatory Effects of the Short Time Exposure to Radiofrequency Radiation
Q34514308Non-canonical features of the Golgi apparatus in bipolar epithelial neural stem cells
Q48032747Notch Activation by Shootin1 Opposing Activities on 2 Ubiquitin Ligases
Q47898518OTX1 regulates cell cycle progression of neural progenitors in the developing cerebral cortex
Q34973654Overexpression of cdk4 and cyclinD1 triggers greater expansion of neural stem cells in the adult mouse brain
Q59333241Pax6 Lengthens G1 Phase and Decreases Oscillating Cdk6 Levels in Murine Embryonic Cortical Progenitors
Q28554321Phosphorylation of Def Regulates Nucleolar p53 Turnover and Cell Cycle Progression through Def Recruitment of Calpain3
Q46629073Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors.
Q38776431Playing with the cell cycle to build the spinal cord
Q50482149Proliferation and cell cycle dynamics in the developing stellate ganglion.
Q26784363Proliferation control in neural stem and progenitor cells
Q30696843Prolonged Mitosis of Neural Progenitors Alters Cell Fate in the Developing Brain
Q93344374Quantitative Clonal Analysis and Single-Cell Transcriptomics Reveal Division Kinetics, Hierarchy, and Fate of Oral Epithelial Progenitor Cells
Q36098844Ranbp1, Deleted in DiGeorge/22q11.2 Deletion Syndrome, is a Microcephaly Gene That Selectively Disrupts Layer 2/3 Cortical Projection Neuron Generation.
Q36243860Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Q52666800Rap1 GTPases Are Master Regulators of Neural Cell Polarity in the Developing Neocortex.
Q35572513Rbm8a haploinsufficiency disrupts embryonic cortical development resulting in microcephaly
Q38389913Regulation of cerebral cortical neurogenesis by the Pax6 transcription factor
Q39437348Regulation of self-renewing neural progenitors by FGF/ERK signaling controls formation of the inferior colliculus
Q41918825Retinoic acid controls early neurogenesis in the developing mouse cerebral cortex
Q28678003Role of maternal thyroid hormones in the developing neocortex and during human evolution
Q37224954S-phase duration is the main target of cell cycle regulation in neural progenitors of developing ferret neocortex
Q54304612SP8 Transcriptional Regulation of Cyclin D1 During Mouse Early Corticogenesis.
Q30651695Slit/Robo signaling modulates the proliferation of central nervous system progenitors
Q33959953Small organelle, big responsibility: the role of centrosomes in development and disease
Q30573858Sonic hedgehog signaling regulates mode of cell division of early cerebral cortex progenitors and increases astrogliogenesis.
Q42461740Specific polar subpopulations of astral microtubules control spindle orientation and symmetric neural stem cell division
Q27347315Sustained Pax6 Expression Generates Primate-like Basal Radial Glia in Developing Mouse Neocortex
Q98184101Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80
Q40121416Terminal Differentiation of Adult Hippocampal Progenitor Cells Is a Step Functionally Dissociable from Proliferation and Is Controlled by Tis21, Id3 and NeuroD2.
Q47290191The Basal Radial Glia Occurs in Marsupials and Underlies the Evolution of an Expanded Neocortex in Therian Mammals
Q37501709The CDK subunit CKS2 counteracts CKS1 to control cyclin A/CDK2 activity in maintaining replicative fidelity and neurodevelopment.
Q47390446The E3 ubiquitin ligase APC/CCdh1 degrades MCPH1 after MCPH1-βTrCP2-Cdc25A-mediated mitotic entry to ensure neurogenesis.
Q88741478The Epigenetic State of PRDM16-Regulated Enhancers in Radial Glia Controls Cortical Neuron Position
Q48488321The Netrin/RGM receptor, Neogenin, controls adult neurogenesis by promoting neuroblast migration and cell cycle exit.
Q93087413The cell cycle in stem cell proliferation, pluripotency and differentiation
Q55256749The loss of the kinases SadA and SadB results in early neuronal apoptosis and a reduced number of progenitors.
Q37955145The multiple roles of the cyclin-dependent kinase inhibitory protein p57(KIP2) in cerebral cortical neurogenesis
Q38985016The pathological consequences of impaired genome integrity in humans; disorders of the DNA replication machinery
Q34219936The scaffold protein Nde1 safeguards the brain genome during S phase of early neural progenitor differentiation
Q37589354The strength of SMAD1/5 activity determines the mode of stem cell division in the developing spinal cord
Q48515615The timing of upper-layer neurogenesis is conferred by sequential derepression and negative feedback from deep-layer neurons.
Q40630970Tight Coupling of Astrocyte pH Dynamics to Epileptiform Activity Revealed by Genetically Encoded pH Sensors
Q50458099Time-lapse imaging of cell cycle dynamics during development in living cardiomyocyte.
Q41018147Tissue-specific targeting of cell fate regulatory genes by E2f factors
Q37586018Topoisomerase IIbeta is required for proper retinal development and survival of postmitotic cells
Q38597727Transcription-Factor-Dependent Control of Adult Hippocampal Neurogenesis
Q47103145Transcriptional and Post-Transcriptional Mechanisms of the Development of Neocortical Lamination
Q28082523Transcriptional control of stem cell fate by E2Fs and pocket proteins
Q47916776Transcriptional profiling of human neural precursors post alcohol exposure reveals impaired neurogenesis via dysregulation of ERK signaling and miR-145.
Q39103827Transcriptional regulation of intermediate progenitor cell generation during hippocampal development.
Q37694046Transcriptome sequencing during mouse brain development identifies long non-coding RNAs functionally involved in neurogenic commitment
Q34323832Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal
Q44132004When size matters: CHD8 in autism
Q48568086Wnt/β-catenin signaling regulates sequential fate decisions of murine cortical precursor cells.
Q64096524YAP Activity Is Necessary and Sufficient for Basal Progenitor Abundance and Proliferation in the Developing Neocortex
Q36081457YAP controls retinal stem cell DNA replication timing and genomic stability
Q24048030Zika Virus Disrupts Neural Progenitor Development and Leads to Microcephaly in Mice
Q42566243aPKC phosphorylates p27Xic1, providing a mechanistic link between apicobasal polarity and cell-cycle control
Q34999217mTOR regulates brain morphogenesis by mediating GSK3 signaling

Search more.