Kainate receptors are primarily postsynaptic to SP-containing axon terminals in the trigeminal dorsal horn

scientific article published on 4 October 2007

Kainate receptors are primarily postsynaptic to SP-containing axon terminals in the trigeminal dorsal horn is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.BRAINRES.2007.09.070
P932PMC publication ID2238683
P698PubMed publication ID17964552
P5875ResearchGate publication ID5880662

P2093author name stringDeborah M Hegarty
Sue A Aicher
Jennifer L Mitchell
Kristin C Swanson
P2860cites workPrimary afferent tachykinins are required to experience moderate to intense painQ28506575
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Presynaptic kainate receptors regulate spinal sensory transmission.Q31813367
Glutamate and substance P coexist in primary afferent terminals in the superficial laminae of spinal cordQ33658035
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Subcellular localization and trafficking of kainate receptors.Q35998170
Kainate receptors.Q36539074
Histological and ultrastructural localization of the kainate receptor subunits, KA2 and GluR6/7, in the rat nervous system using selective antipeptide antibodiesQ36715590
Spinal neurons exhibiting a specific nociceptive response receive abundant substance P-containing synaptic contactsQ37043106
Detection of substance P in the central nervous system by a monoclonal antibodyQ37337676
Opiate analgesics inhibit substance P release from rat trigeminal nucleusQ39156657
Glutamate receptor subunits GluR5 and KA-2 are coexpressed in rat trigeminal ganglion neurons.Q39421008
The pain system. The neural basis of nociceptive transmission in the mammalian nervous systemQ39493023
Optimization of differential immunogold-silver and peroxidase labeling with maintenance of ultrastructure in brain sections before plastic embeddingQ39787502
Spinal and Trigeminal Mechanisms of NociceptionQ40089820
Substance P: Depletion in the dorsal horn of rat spinal cord after section of the peripheral processes of primary sensory neuronsQ40229378
Substance P: Localization in the Central Nervous System and in Some Primary Sensory NeuronsQ40349945
Peptides and the primary afferent nociceptorQ40911083
Distribution of substance P-like immunoreactivity in the central nervous system of the rat—I. Cell bodies and nerve terminalsQ40983250
The origin, distribution and synaptic relationships of substance P axons in rat spinal cordQ40993620
Excitatory amino acid binding sites in the trigeminal principal sensory and spinal trigeminal nuclei of the rat.Q41085382
Potentiation of a behavioural response in mice by spinal coadministration of substance P and excitatory amino acid agonistsQ41141004
The spinal antinociceptive effects of a novel competitive AMPA receptor antagonist, YM872, on thermal or formalin-induced pain in ratsQ41676696
Elevated substance-P-like immunoreactivity levels in spinal dialysates during the formalin test in normal and diabetic ratsQ41719808
Plasticity in the synthesis and storage of substance P and calcitonin gene-related peptide in primary afferent neurons during peripheral inflammationQ42474375
In vivo release of substance P in cat dorsal horn studied with microdialysisQ42487978
Inflammation-induced changes in primary afferent-evoked release of substance P within trigeminal ganglia in vivoQ42490766
mu-Opioid receptors often colocalize with the substance P receptor (NK1) in the trigeminal dorsal horn.Q44331698
Endomorphin-2 axon terminals contact mu-opioid receptor-containing dendrites in trigeminal dorsal hornQ44342007
Behavioural effects of the novel AMPA/GluR5 selective receptor antagonist NS1209 after systemic administration in animal models of experimental painQ44994144
Release of immunoreactive substance P in the spinal cord during development of acute arthritis in the knee joint of the cat: a study with antibody microprobesQ47575135
Kainate GluR5 receptor subtype mediates the nociceptive response to formalin in the rat.Q47782247
Selective distribution of kainate receptor subunit immunoreactivity in monkey neocortex revealed by a monoclonal antibody that recognizes glutamate receptor subunits GluR5/6/7.Q48253736
Alterations in neurokinin A-, substance P- and calcitonin gene-related peptide immunoreactivities in the caudal trigeminal nucleus of the rat following electrical stimulation of the trigeminal ganglionQ48260847
Kainate-receptor-mediated sensory synaptic transmission in mammalian spinal cordQ48297298
Ultrastructural localization of substance P in neurons of rat spinal cordQ48313234
Interactions between excitatory amino acids and tachykinins in the rat spinal dorsal hornQ48391767
The N-methyl-D-aspartate (NMDA) receptor is postsynaptic to substance P-containing axon terminals in the rat superficial dorsal hornQ48580771
Release of substance P into the superficial dorsal horn following nociceptive activation of the hindpaw of the ratQ48607741
Enhancement of spinothalamic neuron responses to chemical and mechanical stimuli following combined micro-iontophoretic application of N-methyl-D-aspartic acid and substance P.Q48649690
Central projection of calcitonin gene-related peptide (CGRP)- and substance P (SP)-immunoreactive trigeminal primary neurons in the rat.Q48798136
Release of immunoreactive substance P in the trigeminal brain stem nuclear complex evoked by chemical stimulation of the nasal mucosa and the dura mater encephali--a study with antibody microprobesQ48825363
Immunocytoehemical localization of substance P in the spinal trigeminal nucleus of the rat: A light and electron microscopic studyQ48884398
Spinal substance P release in vivo during the induction of long-term potentiation in dorsal horn neurons.Q49148003
Interactions between excitatory amino acids and tachykinins and long-term changes of synaptic responses in the rat spinal dorsal hornQ51660608
Substance P and enkephalin immunoreactivities in axonal boutons presynaptic to physiologically identified dorsal horn neurons. An ultrastructural multiple-labelling study in the catQ56886110
Role of kainate receptors in nociceptionQ57767749
Abnormal substance P release from the spinal cord following injury to primary sensory neuronsQ57898681
Intrathecal morphine inhibits substance P release from mammalian spinal cord in vivoQ59061346
Combined application of excitatory amino acids and substance P produces long-lasting changes in responses of primate spinothalamic tract neuronsQ60679915
Neural changes in acute arthritis in monkeys. III. Changes in substance P, calcitonin gene-related peptide and glutamate in the dorsal horn of the spinal cordQ60679922
Substance P- and enkephalin-like immunoreactivities are colocalized in certain neurons of the substantia gelatinosa of the rat spinal cord: an ultrastructural double-labeling studyQ67685882
Glutamate receptor channels in rat DRG neurons: activation by kainate and quisqualate and blockade of desensitization by Con AQ68477606
Release of substance P from the cat spinal cordQ69022182
Survey of distribution of substance P, vasoactive intestinal polypeptide, cholecystokinin, neurotensin, Met-enkephalin, bombesin and PHI in the spinal cord of cat, dog, sloth and monkeyQ69028247
Coexistence of glutamate and substance P in dorsal root ganglion neurons of the rat and monkeyQ69055839
Cutaneous stimuli releasing immunoreactive substance P in the dorsal horn of the catQ69078129
Stimulus specificity of peripherally evoked substance P release from the rabbit dorsal horn in situQ69084852
Selective antinociceptive effect of excitatory amino acid antagonists in intact and acute spinal ratsQ72061477
Dual ultrastructural localization of mu-opiate receptors and substance p in the dorsal hornQ73504575
Noxious cutaneous thermal stimuli induce a graded release of endogenous substance P in the spinal cord: imaging peptide action in vivoQ73507903
Calcitonin gene-related peptide and substance P immunoreactivity in rat trigeminal ganglia and brainstem following adjuvant-induced inflammation of the temporomandibular jointQ73525607
Apparent antinociceptive and anti-inflammatory effects of GYKI 52466Q73910670
Substance PQ74220103
Involvement of spinal substance P and excitatory amino acids in inflammatory hyperalgesia in ratsQ74362903
Ultrastructural analysis of NMDA, AMPA, and kainate receptors on unmyelinated and myelinated axons in the peripheryQ74399440
Spinal substance P receptor expression and internalization in acute, short-term, and long-term inflammatory pain statesQ78166434
Primary afferent NMDA receptors increase dorsal horn excitation and mediate opiate tolerance in neonatal ratsQ79362825
P304page(s)149-159
P577publication date2007-10-04
P1433published inBrain ResearchQ4955782
P1476titleKainate receptors are primarily postsynaptic to SP-containing axon terminals in the trigeminal dorsal horn
P478volume1184

Reverse relations

cites work (P2860)
Q38025661CGRP and NO in the trigeminal system: mechanisms and role in headache generation
Q36007619Distribution of CB1 cannabinoid receptors and their relationship with mu-opioid receptors in the rat periaqueductal gray
Q37772543Glutamate receptor phosphorylation and trafficking in pain plasticity in spinal cord dorsal horn
Q37624494Ionotropic glutamate receptors in spinal nociceptive processing.
Q39453331Kainate receptors mediate regulated exocytosis of secretory phospholipase A(2) in SH-SY5Y neuroblastoma cells
Q41447707Peripheral nerve injury increases glutamate-evoked calcium mobilization in adult spinal cord neurons
Q33900700Physiological temperatures drive glutamate release onto trigeminal superficial dorsal horn neurons

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