Regulation of Fas receptor/Fas-associated protein with death domain apoptotic complex and associated signalling systems by cannabinoid receptors in the mouse brain.

scientific article published on June 2010

Regulation of Fas receptor/Fas-associated protein with death domain apoptotic complex and associated signalling systems by cannabinoid receptors in the mouse brain. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1476-5381.2010.00710.X
P932PMC publication ID2931564
P698PubMed publication ID20590568
P5875ResearchGate publication ID44887517

P50authorSusana EstebanQ42761568
P2093author name stringJ A García-Sevilla
J Manzanares
O Valverde
M S García-Gutiérrez
M Alvaro-Bartolomé
P2860cites workFADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosisQ24307362
The Fas-FADD death domain complex structure unravels signalling by receptor clusteringQ24312945
Differential effects of cannabinoid receptor agonists on regional brain activity using pharmacological MRI.Q24643957
Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneuronsQ28144567
Phosphorylation of FADD at serine 194 by CKIalpha regulates its nonapoptotic activitiesQ28265029
Cannabinoid signallingQ28267949
Regulation of the extrinsic and intrinsic apoptotic pathways in the prefrontal cortex of short- and long-term human opiate abusersQ28296007
Chronic morphine induces up-regulation of the pro-apoptotic Fas receptor and down-regulation of the anti-apoptotic Bcl-2 oncoprotein in rat brainQ28363748
Tetrahydrocannabinol‐induced neurotoxicity depends on CB1 receptor‐mediated c‐Jun N‐terminal kinase activation in cultured cortical neuronsQ28565561
Effect of cocaine on Fas-associated protein with death domain in the rat brain: individual differences in a model of differential vulnerability to drug abuseQ28574580
Opioid receptor agonists enhance the phosphorylation state of Fas-associated death domain (FADD) protein in the rat brain: functional interactions with casein kinase Ialpha, Galpha(i) proteins, and ERK1/2 signalingQ28575106
The time course of unconditioned morphine-induced psychomotor sensitization mirrors the phosphorylation of FADD and MEK/ERK in rat striatum: role of PEA-15 as a FADD-ERK binding partner in striatal plasticityQ28580593
Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic studyQ29615905
Cannabinoid CB2 receptors: Immunohistochemical localization in rat brainQ30047898
Cannabinoid agonist WIN55,212-2 induces apoptosis in cerebellar granule cells via activation of the CB1 receptor and downregulation of bcl-xL gene expressionQ33239704
Mechanisms of control of neuron survival by the endocannabinoid systemQ33368214
CB2 receptor ligandsQ33988721
Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteinsQ34306079
Inverse agonism and neutral antagonism at cannabinoid CB1 receptorsQ34388049
Pharmacology of cannabinoid CB1 and CB2 receptors.Q34442847
Cannabinoids and cell fate.Q34786842
In vivo cellular and molecular mechanisms of neuronal apoptosis in the mammalian CNS.Q35145656
The endocannabinoid system, anandamide and the regulation of mammalian cell apoptosisQ35204851
Regulation of cannabinoid CB1 receptors in the central nervous system by chronic cannabinoidsQ35672460
FADD and its phosphorylationQ35951072
Analysis of the endocannabinoid system by using CB1 cannabinoid receptor knockout mice.Q36441179
Caspase function in programmed cell deathQ36643566
WIN55,212-2, a cannabinoid receptor agonist, protects against nigrostriatal cell loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.Q37371387
Mitochondrial membrane permeabilization in neuronal injuryQ37526353
Molecular ordering of the initial signaling events of CD95.Q39676008
Role of delta-opioid receptor function in neurogenesis and neuroprotectionQ40280641
Constitutive endocytic cycle of the CB1 cannabinoid receptor.Q40542809
Constitutive activity of the cannabinoid CB1 receptor regulates the function of co-expressed Mu opioid receptorsQ42525438
Behavioral and molecular changes elicited by acute administration of SR141716 to Delta9-tetrahydrocannabinol-tolerant rats: an experimental model of cannabinoid abstinenceQ42625437
Biphasic effects of anandamideQ43332781
Immunomodulation by cannabinoids is absent in mice deficient for the cannabinoid CB(2) receptorQ43503403
Anandamide degradation and N-acylethanolamines level in wild-type and CB1 cannabinoid receptor knockout mice of different agesQ43681018
Delta 9-tetrahydrocannabinol-induced MAPK/ERK and Elk-1 activation in vivo depends on dopaminergic transmission.Q43734938
Effects of constitutive deletion of opioid receptors on the basal densities of Fas and Fas-associated protein with death domain (FADD) in the mouse brain: a delta-opioid tone inhibits FADD.Q44332344
Kappa- and delta-opioid receptor functional activities are increased in the caudate putamen of cannabinoid CB1 receptor knockout miceQ44350888
Phosphorylation of FADD (Fas-associated death domain protein) at serine 194 is increased in the prefrontal cortex of opiate abusers: relation to mitogen activated protein kinase, phosphoprotein enriched in astrocytes of 15 kDa, and Akt signaling patQ46079632
Blood, adipose tissue and brain levels of the cannabinoid ligands WIN-55,212 and SR-141716A after their intraperitoneal injection in mice: compound-specific and area-specific distribution within the brainQ46079782
Effects of opiate drugs on Fas-associated protein with death domain (FADD) and effector caspases in the rat brain: regulation by the ERK1/2 MAP kinase pathway.Q46947457
A comparison of the apoptotic effect of Delta(9)-tetrahydrocannabinol in the neonatal and adult rat cerebral cortexQ46990151
Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout miceQ47994629
Selective CB2 receptor agonism protects central neurons from remote axotomy-induced apoptosis through the PI3K/Akt pathway.Q48028956
The CB1 cannabinoid receptor mediates excitotoxicity-induced neural progenitor proliferation and neurogenesisQ48143381
Regulation of PI3K/Akt/GSK-3 pathway by cannabinoids in the brain.Q48176645
Acute, chronic and withdrawal effects of the cannabinoid receptor agonist WIN55212-2 on the sequential activation of MAPK/Raf-MEK-ERK signaling in the rat cerebral frontal cortex: short-term regulation by intrinsic and extrinsic pathwaysQ48350845
CB1 receptor stimulation in specific brain areas differently modulate anxiety-related behaviour.Q50891805
Guide to Receptors and Channels (GRAC), 4th EditionQ56639335
Direct Quantitation of Poly(ADP-Ribose) Polymerase (PARP) Activity as a Means to Distinguish Necrotic and Apoptotic Death in Cell and Tissue SamplesQ61651216
Electrically evoked acetylcholine release from hippocampal slices is inhibited by the cannabinoid receptor agonist, WIN 55212-2, and is potentiated by the cannabinoid antagonist, SR 141716AQ71152696
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectcannabinoid receptorQ421237
cannabinoidsQ422936
apoptotic processQ14599311
CNR2Q17907844
P304page(s)643-656
P577publication date2010-06-01
P1433published inBritish Journal of PharmacologyQ919631
P1476titleRegulation of Fas receptor/Fas-associated protein with death domain apoptotic complex and associated signalling systems by cannabinoid receptors in the mouse brain
P478volume160

Reverse relations

cites work (P2860)
Q34163269Cholecystokinin octapeptide antagonizes apoptosis in human retinal pigment epithelial cells
Q45851009Chronic treatment with selective I2-imidazoline receptor ligands decreases the content of pro-apoptotic markers in rat brain
Q38527077Decreased proliferation of adult hippocampal stem cells during cocaine withdrawal: possible role of the cell fate regulator FADD.
Q38593120Genetic Manipulation of the Endocannabinoid System
Q52646112Prenatal exposure to the CB1 and CB2 cannabinoid receptor agonist WIN 55,212-2 alters migration of early-born glutamatergic neurons and GABAergic interneurons in the rat cerebral cortex.
Q48337573Regulation of cannabinoid CB2 receptor constitutive activity in vivo: repeated treatments with inverse agonists reverse the acute activation of JNK and associated apoptotic signaling in mouse brain
Q47742909Synergistic interaction of the cannabinoid and death receptor systems - a potential target for future cancer therapies?
Q36127141The synthetic cannabinoid R(+)WIN55,212-2 augments interferon-β expression via peroxisome proliferator-activated receptor-α.

Search more.