Current concepts in the treatment of retinitis pigmentosa

scientific article published on 11 October 2010

Current concepts in the treatment of retinitis pigmentosa is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1155/2011/753547
P932PMC publication ID2964907
P698PubMed publication ID21048997
P5875ResearchGate publication ID47676740

P2093author name stringMaria A Musarella
Ian M Macdonald
P2860cites workRetinitis pigmentosaQ21203028
Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trialQ24608049
Safety and efficacy of gene transfer for Leber's congenital amaurosisQ24634724
A system for stable expression of short interfering RNAs in mammalian cellsQ27860875
Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trialQ28262431
Effect of gene therapy on visual function in Leber's congenital amaurosisQ28277981
CNTF induces regeneration of cone outer segments in a rat model of retinal degenerationQ28572876
Artificial visionQ31998312
AAV-mediated delivery of ciliary neurotrophic factor prolongs photoreceptor survival in the rhodopsin knockout mouseQ32125104
Reversal of blindness in animal models of leber congenital amaurosis using optimized AAV2-mediated gene transferQ33315634
How strong is the evidence that nutritional supplements slow the progression of retinitis pigmentosa?Q84046902
Oxidative damage is a potential cause of cone cell death in retinitis pigmentosaQ45297114
Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa.Q45888779
Visual performance using a retinal prosthesis in three subjects with retinitis pigmentosaQ46124003
Survival, migration and differentiation of retinal progenitor cells transplanted on micro-machined poly(methyl methacrylate) scaffolds to the subretinal spaceQ46182791
Vision improvement in retinal degeneration patients by implantation of retina together with retinal pigment epitheliumQ46545312
Measurement and prediction of lateral diffusion within human scleraQ50108649
Treatment of cystoid macular edema in retinitis pigmentosa with intravitreal triamcinoloneQ56995106
Vitamin A supplementation for retinitis pigmentosaQ72607086
Expression of a mutant opsin gene increases the susceptibility of the retina to light damageQ73125183
Efficacy of dorzolamide hydrochloride in the management of chronic cystoid macular edema in patients with retinitis pigmentosaQ73444647
Ribozyme-targeted destruction of RNA associated with autosomal-dominant retinitis pigmentosaQ74431990
Treatment with carbonic anhydrase inhibitors depresses electroretinogram responsiveness in miceQ79649597
Pharmacokinetics of intraocular drug delivery by periocular injections using ocular fluorophotometryQ80219541
Ocular drug deliveryQ82682873
Identifying photoreceptors in blind eyes caused by RPE65 mutations: Prerequisite for human gene therapy successQ33771032
Retinal dystrophy of Swedish briard/briard-beagle dogs is due to a 4-bp deletion in RPE65.Q33857732
Drug delivery for posterior segment eye diseaseQ33884553
The role of carbonic anhydrase inhibitors in the management of macular edemaQ33969534
Clinical trial of lutein in patients with retinitis pigmentosa receiving vitamin AQ34330189
A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosaQ34366637
Ciliary neurotrophic factor (CNTF) for human retinal degeneration: phase I trial of CNTF delivered by encapsulated cell intraocular implantsQ34410761
Subretinal electrical stimulation of the rabbit retinaQ34425297
Retinal repair by transplantation of photoreceptor precursorsQ34580415
Retinal prosthesis for the blindQ34772724
Leber congenital amaurosis: genes, proteins and disease mechanismsQ34796759
Folding and activity of the hammerhead ribozymeQ34804270
Efficient generation of retinal progenitor cells from human embryonic stem cells.Q35036440
Retinal laminar architecture in human retinitis pigmentosa caused by Rhodopsin gene mutationsQ35229775
Ribozyme rescue of photoreceptor cells in P23H transgenic rats: long-term survival and late-stage therapy.Q35306158
Stem cells as tools in regenerative therapy for retinal degenerationQ35335016
An overview of Leber congenital amaurosis: a model to understand human retinal developmentQ35825163
Potential applications for RNAi to probe pathogenesis and develop new treatments for ocular disordersQ36272954
Perspective on genes and mutations causing retinitis pigmentosaQ36734545
Searching genomes for ribozymes and riboswitchesQ36808113
Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindnessQ36825024
Leber congenital amaurosis: disease, genetics and therapyQ37063535
Gene therapy for retinitis pigmentosa and Leber congenital amaurosis caused by defects in AIPL1: effective rescue of mouse models of partial and complete Aipl1 deficiency using AAV2/2 and AAV2/8 vectorsQ37292973
Leber congenital amaurosis: clinical correlations with genotypes, gene therapy trials update, and future directionsQ37652856
Feasibility study of a retinal prosthesis: spatial vision with a 16-electrode implantQ38382437
Extraocular surgery for implantation of an active subretinal visual prosthesis with external connections: feasibility and outcome in seven patients.Q39316492
Human embryonic stem cell-derived cells rescue visual function in dystrophic RCS rats.Q40225932
Safety in nonhuman primates of ocular AAV2-RPE65, a candidate treatment for blindness in Leber congenital amaurosisQ40292682
Impairment of the transient pupillary light reflex in Rpe65(-/-) mice and humans with leber congenital amaurosisQ40523047
Recombinant adeno-associated virus serotype 4 mediates unique and exclusive long-term transduction of retinal pigmented epithelium in rat, dog, and nonhuman primate after subretinal deliveryQ40583540
Encapsulated cell-based delivery of CNTF reduces photoreceptor degeneration in animal models of retinitis pigmentosa.Q40700552
Glial cell line-derived neurotrophic factor induces histologic and functional protection of rod photoreceptors in the rd/rd mouse.Q40925242
The development of subretinal microphotodiodes for replacement of degenerated photoreceptors.Q41607442
Photoreceptor layer topography in children with leber congenital amaurosis caused by RPE65 mutationsQ42119219
Gene therapy restores vision in a canine model of childhood blindnessQ43590733
Preliminary results of gene therapy for retinal degeneration.Q43604527
Long-term protection of retinal structure but not function using RAAV.CNTF in animal models of retinitis pigmentosaQ43715205
Effects of adeno-associated virus-vectored ciliary neurotrophic factor on retinal structure and function in mice with a P216L rds/peripherin mutationQ44070483
A randomized, placebo-controlled clinical trial of docosahexaenoic acid supplementation for X-linked retinitis pigmentosa.Q44826779
Clinical trial of docosahexaenoic acid in patients with retinitis pigmentosa receiving vitamin A treatmentQ45056943
Further evaluation of docosahexaenoic acid in patients with retinitis pigmentosa receiving vitamin A treatment: subgroup analysesQ45056945
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P304page(s)753547
P577publication date2010-10-11
P1433published inJournal of OphthalmologyQ26842872
P1476titleCurrent concepts in the treatment of retinitis pigmentosa
P478volume2011

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cites work (P2860)
Q38459803Association between multifocal electroretinograms, optical coherence tomography and central visual sensitivity in advanced retinitis pigmentosa
Q37963356Clinical and Rehabilitative Management of Retinitis Pigmentosa: Up-to-Date
Q39037025Comparative study of human embryonic stem cells (hESC) and human induced pluripotent stem cells (hiPSC) as a treatment for retinal dystrophies
Q38047615Current mutation discovery approaches in Retinitis Pigmentosa.
Q36928951Detection of G protein-selective G protein-coupled receptor (GPCR) conformations in live cells
Q35512477Effect of purified murine NGF on isolated photoreceptors of a rodent developing retinitis pigmentosa
Q92155447Enhanced Visual Attentional Modulation in Patients with Inherited Peripheral Retinal Degeneration in the Absence of Cortical Degeneration
Q35910875Long-term survival and differentiation of retinal neurons derived from human embryonic stem cell lines in un-immunosuppressed mouse retina
Q38160865Plasticity in the human visual cortex: an ophthalmology-based perspective.
Q38766595Primary visual cortical remapping in patients with inherited peripheral retinal degeneration.
Q36469478Proinsulin slows retinal degeneration and vision loss in the P23H rat model of retinitis pigmentosa
Q38793189Protection against oxidative stress by vitamin D in cone cells
Q41039747Protective effects of naringenin eye drops on N-methyl-N-nitrosourea-induced photoreceptor cell death in rats
Q30659582Resolving the genetic heterogeneity of prelingual hearing loss within one family: Performance comparison and application of two targeted next generation sequencing approaches.
Q38540535Retinitis Pigmentosa Treatment with Western Medicine and Traditional Chinese Medicine Therapies
Q35092179Retinitis pigmentosa: genes and disease mechanisms.
Q38770786Seeing through their eyes: lived experiences of people with retinitis pigmentosa.
Q35015829Spotlight on childhood blindness
Q53178701Surgical feasibility and biocompatibility of wide-field dual-array suprachoroidal-transretinal stimulation prosthesis in middle-sized animals.
Q42548280Sustained gene expression in the retina by improved episomal vectors
Q35092187Therapeutic challenges to retinitis pigmentosa: from neuroprotection to gene therapy.

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