Functional implications of Neandertal introgression in modern humans

scientific article published on 3 April 2017

Functional implications of Neandertal introgression in modern humans is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1084252045
P356DOI10.1186/S13059-017-1181-7
P2888exact matchhttps://scigraph.springernature.com/pub.10.1186/s13059-017-1181-7
P932PMC publication ID5376702
P698PubMed publication ID28366169

P50authorJanet KelsoQ26896948
Michael DannemannQ28805283
Kay PrüferQ30093284
P2860cites workGenome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosisQ21144954
Differential expression analysis for sequence count dataQ21184103
Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locusQ24630434
Hundreds of variants clustered in genomic loci and biological pathways affect human heightQ24630979
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary functionQ24633262
Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variantsQ24633806
Multiple loci influence erythrocyte phenotypes in the CHARGE ConsortiumQ24655591
PLINK: a tool set for whole-genome association and population-based linkage analysesQ24677407
A global reference for human genetic variationQ25909434
A method and server for predicting damaging missense mutationsQ27860835
Evolution at two levels in humans and chimpanzeesQ28141105
Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNAQ28244310
Genome-wide association study identifies multiple loci influencing human serum metabolite levelsQ28258384
Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAXQ28265206
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk lociQ28281906
A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility lociQ28293771
The complete genome sequence of a Neanderthal from the Altai MountainsQ28304347
Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary functionQ28392223
Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanismsQ28477763
Introgression of Neandertal- and Denisovan-like Haplotypes Contributes to Adaptive Variation in Human Toll-like ReceptorsQ28602436
The phenotypic legacy of admixture between modern humans and NeandertalsQ28603615
The Genotype-Tissue Expression (GTEx) projectQ28657968
Discovery and refinement of loci associated with lipid levelsQ28661470
Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility lociQ28924378
Germline genomic variants associated with childhood acute lymphoblastic leukemiaQ28924384
Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotypeQ28943255
Parkinson disease loci in the mid-western AmishQ28943294
Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosisQ28943317
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in AsiansQ28943338
A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility lociQ28943492
Functional variants in NFKBIE and RTKN2 involved in activation of the NF-κB pathway are associated with rheumatoid arthritis in JapaneseQ28943519
Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategyQ29417020
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility lociQ29417047
Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody productionQ29417056
Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithmQ29547194
A high-resolution recombination map of the human genomeQ29547815
The evolution of gene expression levels in mammalian organsQ29617170
A genome-wide investigation of SNPs and CNVs in schizophreniaQ33406258
Signatures of Archaic Adaptive Introgression in Present-Day Human PopulationsQ33590851
Archaic Adaptive Introgression in TBX15/WARS2.Q33681777
Genome-wide association study identifies variants at the IL18-BCO2 locus associated with interleukin-18 levelsQ33740363
Novel gene variants predict serum levels of the cytokines IL-18 and IL-1ra in older adultsQ33767339
The genomic landscape of Neanderthal ancestry in present-day humansQ33812612
Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human PopulationsQ34047556
A genome-wide association study of metabolic traits in human urineQ34185066
Neandertal origin of genetic variation at the cluster of OAS immunity genesQ34322389
Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humansQ34475541
Genome-wide patterns of selection in 230 ancient EurasiansQ34502635
The genetic history of Ice Age EuropeQ34524590
Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource studyQ34955404
GWAS of butyrylcholinesterase activity identifies four novel loci, independent effects within BCHE and secondary associations with metabolic risk factorsQ35389546
GWASdb: a database for human genetic variants identified by genome-wide association studiesQ35630781
The Genetic Cost of Neanderthal IntrogressionQ35977651
Genome-wide associated loci influencing interleukin (IL)-10, IL-1Ra, and IL-6 levels in African AmericansQ36161753
A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q.Q36166323
The Strength of Selection against Neanderthal IntrogressionQ36185525
Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity GenesQ36473385
Evolution of primate gene expressionQ36572075
Genetic correction of PSA values using sequence variants associated with PSA levelsQ36588082
Seventy-five genetic loci influencing the human red blood cellQ36758500
The Ensembl Variant Effect PredictorQ36970975
A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility lociQ37153818
Adaptively introgressed Neandertal haplotype at the OAS locus functionally impacts innate immune responses in humans.Q37455468
Neanderthal ancestry drives evolution of lipid catabolism in contemporary EuropeansQ37706187
The prevalence of Parkinson's disease: a systematic review and meta-analysisQ38224356
Genetic Ancestry and Natural Selection Drive Population Differences in Immune Responses to PathogensQ40494104
A genome-wide association study of BMI in American IndiansQ43668665
A genome-wide association study of acenocoumarol maintenance dosage.Q45939541
Identification of genetic loci associated with Helicobacter pylori serologic status.Q51012428
Archaic Hominin Admixture Facilitated Adaptation to Out-of-Africa Environments.Q53746186
A nonsynonymous SNP in PRKCH (protein kinase C eta) increases the risk of cerebral infarctionQ79500818
P4510describes a project that usesDESeq2Q113018293
P433issue1
P921main subjectNeanderthalQ40171
P304page(s)61
P577publication date2017-04-03
P1433published inGenome BiologyQ5533480
P1476titleFunctional implications of Neandertal introgression in modern humans
P478volume18

Reverse relations

cites work (P2860)
Q97686508A Neanderthal Sodium Channel Increases Pain Sensitivity in Present-Day Humans
Q64972623A catalog of single nucleotide changes distinguishing modern humans from archaic hominins.
Q83227526An evolutionary recent IFN/IL-6/CEBP axis is linked to monocyte expansion and tuberculosis severity in humans
Q57199566Detecting archaic introgression using an unadmixed outgroup
Q56396355Evolutionary and Medical Consequences of Archaic Introgression into Modern Human Genomes
Q92392705Functional consequences of archaic introgression and their impact on fitness
Q90575782Functional divergence among hominins
Q46309376Harnessing ancient genomes to study the history of human adaptation
Q96591197Human Stem Cell Resources Are an Inroad to Neandertal DNA Functions
Q92471090Impact and Evolutionary Determinants of Neanderthal Introgression on Transcriptional and Post-Transcriptional Regulation
Q90575788Inferred divergent gene regulation in archaic hominins reveals potential phenotypic differences
Q60670737Limits of long-term selection against Neandertal introgression
Q88231247Model-based detection and analysis of introgressed Neanderthal ancestry in modern humans
Q59702213Neandertal Introgression Sheds Light on Modern Human Endocranial Globularity
Q97905413Neanderthal introgression reintroduced functional ancestral alleles lost in Eurasian populations
Q55397791Outstanding questions in the study of archaic hominin admixture.
Q90089204Population structure of modern-day Italians reveals patterns of ancient and archaic ancestries in Southern Europe
Q98665150Selection against archaic hominin genetic variation in regulatory regions
Q61797653Skeletal Anomalies in The Neandertal Family of El Sidrón (Spain) Support A Role of Inbreeding in Neandertal Extinction
Q47189890The Contribution of Neanderthals to Phenotypic Variation in Modern Humans
Q96132193The nature of Neanderthal introgression revealed by 27,566 Icelandic genomes
Q91765054Using Haplotype Information for Conservation Genomics
Q46772059Variation and functional impact of Neanderthal ancestry in Western Asia

Search more.