scholarly article | Q13442814 |
P50 | author | Marta Filizola | Q41045386 |
P2093 | author name string | Ana Negri | |
Barry S Coller | |||
Davide Provasi | |||
P2860 | cites work | Determination of the Border between the Transmembrane and Cytoplasmic Domains of Human Integrin Subunits | Q57083866 |
The inner world of cell adhesion: integrin cytoplasmic domains | Q75293376 | ||
The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling | Q24320948 | ||
Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects | Q24657848 | ||
A specific interface between integrin transmembrane helices and affinity for ligand | Q24793060 | ||
A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face | Q27639651 | ||
Structure of the integrin beta3 transmembrane segment in phospholipid bicelles and detergent micelles | Q27649993 | ||
Structure of the Integrin IIb Transmembrane Segment | Q27650343 | ||
Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces | Q27653293 | ||
The structure of an integrin/talin complex reveals the basis of inside-out signal transduction. | Q27657634 | ||
Structure of an integrin IIb 3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation | Q27657684 | ||
NMR analysis of the αIIbβ3 cytoplasmic interaction suggests a mechanism for integrin regulation | Q27666309 | ||
All-atom empirical potential for molecular modeling and dynamics studies of proteins | Q27860468 | ||
Integrins: bidirectional, allosteric signaling machines | Q27860700 | ||
The phosphotyrosine binding-like domain of talin activates integrins | Q28212748 | ||
Kindlin-3 is essential for integrin activation and platelet aggregation | Q28595084 | ||
Extending the treatment of backbone energetics in protein force fields: limitations of gas-phase quantum mechanics in reproducing protein conformational distributions in molecular dynamics simulations | Q29547631 | ||
Structural basis of integrin regulation and signaling | Q29617618 | ||
Prediction of membrane protein structures with complex topologies using limited constraints | Q30374712 | ||
Determination of N- and C-terminal borders of the transmembrane domain of integrin subunits | Q33199390 | ||
The GPIIb/IIIa (integrin alphaIIbbeta3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend | Q33381441 | ||
Recreation of the terminal events in physiological integrin activation | Q33616477 | ||
A push-pull mechanism for regulating integrin function | Q33817633 | ||
Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering. | Q33928601 | ||
The final steps of integrin activation: the end game | Q34106011 | ||
Kindlins, Integrin Activation and the Regulation of Talin Recruitment to αIIbβ3 | Q34212141 | ||
Tests of Integrin Transmembrane Domain Homo-oligomerization during Integrin Ligand Binding and Signaling | Q34503113 | ||
Conformational changes in talin on binding to anionic phospholipid membranes facilitate signaling by integrin transmembrane helices | Q35034161 | ||
Multiscale simulations suggest a mechanism for integrin inside-out activation | Q35123059 | ||
Intact αIIbβ3 Integrin Is Extended after Activation as Measured by Solution X-ray Scattering and Electron Microscopy | Q35266840 | ||
Affinity of talin-1 for the β3-integrin cytosolic domain is modulated by its phospholipid bilayer environment. | Q35735180 | ||
Talin activates integrins by altering the topology of the β transmembrane domain | Q36002154 | ||
Requirement of alpha and beta subunit transmembrane helix separation for integrin outside-in signaling | Q36007725 | ||
Toward high-resolution prediction and design of transmembrane helical protein structures | Q36023705 | ||
Interactions of platelet integrin alphaIIb and beta3 transmembrane domains in mammalian cell membranes and their role in integrin activation | Q37187555 | ||
On the activation of integrin αIIbβ3: outside-in and inside-out pathways | Q37204375 | ||
Molecular mechanism of inside‐out integrin regulation | Q37903927 | ||
Integrin bi‐directional signaling across the plasma membrane | Q38024314 | ||
The structure of a receptor with two associating transmembrane domains on the cell surface: integrin alphaIIbbeta3. | Q41543290 | ||
Integrin αIIbβ3 inside-out activation: an in situ conformational analysis reveals a new mechanism | Q41952463 | ||
The structure of the talin/integrin complex at a lipid bilayer: an NMR and MD simulation study | Q42588609 | ||
Simulaid: A simulation facilitator and analysis program | Q42925390 | ||
Breaking the integrin hinge. A defined structural constraint regulates integrin signaling | Q43482152 | ||
Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling | Q44136286 | ||
Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins | Q44590985 | ||
Transmembrane domain helix packing stabilizes integrin alphaIIbbeta3 in the low affinity state | Q45182918 | ||
Computational design of peptides that target transmembrane helices | Q51035378 | ||
TRAJELIX: a computational tool for the geometric characterization of protein helices during molecular dynamics simulations | Q51939563 | ||
Anton, a special-purpose machine for molecular dynamics simulation | Q56019494 | ||
P433 | issue | 12 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 3231-3240 | |
P577 | publication date | 2014-09-25 | |
P1433 | published in | Proteins | Q7251514 |
P1476 | title | Talin-driven inside-out activation mechanism of platelet αIIbβ3 integrin probed by multimicrosecond, all-atom molecular dynamics simulations | |
P478 | volume | 82 |
Q37369037 | A model for cyclic mechanical reinforcement |
Q64245553 | Emerging Diversity in Lipid-Protein Interactions |
Q92020137 | Kindlin Is Mechanosensitive: Force-Induced Conformational Switch Mediates Cross-Talk among Integrins |
Q46703119 | Mechanisms of integrin and filamin binding and their interplay with talin during early focal adhesion formation |
Q51347457 | No genetic abnormalities identified in α2IIb and β3: phenotype overcomes genotype in Glanzmann thrombasthenia |
Q52365137 | Regulation of inside-out β1-integrin activation by CDCP1. |
Q39552692 | The Integrin Receptor in Biologically Relevant Bilayers: Insights from Molecular Dynamics Simulations. |
Q41271593 | The dual structural roles of the membrane distal region of the α-integrin cytoplasmic tail during integrin inside-out activation |
Q90389303 | [Special type of Glanzmann's thrombasthenia] |
Q58122368 | [The progresses in research and treatment of inherited platelet disorders] |
Q46767135 | α-Actinin Induces a Kink in the Transmembrane Domain of β3-Integrin and Impairs Activation via Talin |
Q33421611 | αIIbβ3 variants defined by next-generation sequencing: predicting variants likely to cause Glanzmann thrombasthenia |
Q36955873 | αIIbβ3: structure and function |
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