Human memory B cells originate from three distinct germinal center-dependent and -independent maturation pathways

scientific article published on 20 June 2011

Human memory B cells originate from three distinct germinal center-dependent and -independent maturation pathways is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1182/BLOOD-2011-04-345579
P932PMC publication ID3342861
P698PubMed publication ID21690558
P5875ResearchGate publication ID51235895

P50authorMirjam van der BurgQ59687559
Jacques Van DongenQ60655923
Gertjan J A DriessenQ117812639
Menno C van ZelmQ37834763
Andrea CeruttiQ54149079
P2093author name stringBing He
Katharina Biermann
Johan F Lange
Kostas Stamatopoulos
Vasilis Bikos
Christina Grosserichter-Wagener
Magdalena A Berkowska
P2860cites workSelective generation of functional somatically mutated IgM+CD27+, but not Ig isotype-switched, memory B cells in X-linked lymphoproliferative diseaseQ24536218
Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+ CD27+ CD43+ CD70-Q24594899
Leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) is differentially expressed during human B cell differentiation and inhibits B cell receptor-mediated signalingQ28146088
Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survivalQ28205125
DCs induce CD40-independent immunoglobulin class switching through BLyS and APRILQ28216755
Human intestinal IgA response is generated in the organized gut-associated lymphoid tissue but not in the lamina propria.Q54660349
A Theory of Self-Nonself Discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectivelyQ55888521
Intestinal Bacteria Trigger T Cell-Independent Immunoglobulin A2 Class Switching by Inducing Epithelial-Cell Secretion of the Cytokine APRILQ58493951
Different subclass distribution of IgA-producing cells in human lymphoid organs and various secretory tissuesQ68873188
B cell subpopulations separated by CD27 and crucial collaboration of CD27+ B cells and helper T cells in immunoglobulin productionQ73691812
A new population of cells lacking expression of CD27 represents a notable component of the B cell memory compartment in systemic lupus erythematosusQ80257443
Class-switch recombination: interplay of transcription, DNA deamination and DNA repairQ28269740
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzymeQ29547201
Germinal centersQ29616234
Predominant autoantibody production by early human B cell precursorsQ29619656
Biased VH gene usage in early lineage human B cells: evidence for preferential Ig gene rearrangement in the absence of selection.Q30755150
CD27(-) B-cells produce class switched and somatically hyper-mutated antibodies during chronic HIV-1 infectionQ33438469
Analysis of somatic mutation in five B cell subsets of human tonsilQ34328629
ABCB1 transporter discriminates human resting naive B cells from cycling transitional and memory B cellsQ34463998
Targeting of somatic hypermutationQ34551108
Nucleotide sequence analysis of the V regions of two IgM cold agglutinins. Evidence that the VH4-21 gene segment is responsible for the major cross-reactive idiotypeQ34581434
CD40-CD40L independent Ig gene hypermutation suggests a second B cell diversification pathway in humansQ34651496
The biology of intestinal immunoglobulin A responsesQ34673861
B lymphocytes: how they develop and function.Q34813171
Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell toleranceQ36041818
Replication history of B lymphocytes reveals homeostatic proliferation and extensive antigen-induced B cell expansionQ36267196
Ordered rearrangement of immunoglobulin heavy chain variable region segmentsQ36586574
Human marginal zone B cells.Q37419372
Absence of IgD-CD27(+) memory B cell population in X-linked hyper-IgM syndromeQ39808469
T cell independent antigensQ40404858
Immunological memory and protective immunity: understanding their relationQ40969823
Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoireQ41505077
Molecular footprints of a germinal center derivation of human IgM+(IgD+)CD27+ B cells and the dynamics of memory B cell generationQ41763906
Identification of functional human splenic memory B cells by expression of CD148 and CD27.Q42143611
Germinal centers in human lymph nodes contain reactivated memory B cellsQ42767398
Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies.Q42940097
Multiple layers of B cell memory with different effector functionsQ43255281
The cleavage efficiency of the human immunoglobulin heavy chain VH elements by the RAG complex: implications for the immune repertoireQ43470902
Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesisQ43586184
In situ class switching and differentiation to IgA-producing cells in the gut lamina propriaQ43776134
Representation of rearranged VH gene segments in the human adult antibody repertoireQ45083280
Deficiency of somatic hypermutation of the antibody light chain is associated with increased frequency of severe respiratory tract infection in common variable immunodeficiencyQ47926953
Evidence for a large compartment of IgM-expressing memory B cells in humans.Q48053871
Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reactionQ48072572
Resting human memory B cells are intrinsically programmed for enhanced survival and responsiveness to diverse stimuli compared to naive B cells.Q51959485
A new memory CD27-IgG+ B cell population in peripheral blood expressing VH genes with low frequency of somatic mutation.Q51979661
B-cell development: a comparison between mouse and man.Q52182974
Problems in using statistical analysis of replacement and silent mutations in antibody genes for determining antigen-driven affinity selection.Q52992155
Lambda light chain revision in the human intestinal IgA response.Q53040832
Gut IgA class switch recombination in the absence of CD40 does not occur in the lamina propria and is independent of germinal centers.Q54570939
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectmemory B cellQ1195394
P304page(s)2150-2158
P577publication date2011-06-20
P1433published inBloodQ885070
P1476titleHuman memory B cells originate from three distinct germinal center-dependent and -independent maturation pathways
P478volume118

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