Can agrin cerebrospinal fluid concentration be used as an early biomarker for Alzheimer's disease?

scientific article published on 29 March 2015

Can agrin cerebrospinal fluid concentration be used as an early biomarker for Alzheimer's disease? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.DADM.2014.11.008
P932PMC publication ID4876904
P698PubMed publication ID27239494
P5875ResearchGate publication ID277649053

P50authorPhilip ScheltensQ22280357
Connie JimenezQ56887123
Charlotte TeunissenQ56887227
Marta Del Campo MilanQ85840992
P2093author name stringLeah Zuroff
P2860cites workAlzheimer Disease in the US PopulationQ22253055
Agrin binds to beta-amyloid (Abeta), accelerates abeta fibril formation, and is localized to Abeta deposits in Alzheimer's disease brainQ22253180
A two disulfide bridge Kazal domain from Phytophthora exhibits stable inhibitory activity against serine proteases of the subtilisin familyQ24816498
Agrin in the developing CNS: new roles for a synapse organizerQ28203484
Agrin in Alzheimer's disease: altered solubility and abnormal distribution within microvasculature and brain parenchymaQ28645584
Alzheimer's diseaseQ29616743
A novel disulfide pattern in laminin-type epidermal growth factor-like (LE) modules of laminin β1 and γ1 chainsQ30318595
On the beta-binomial model for analysis of spectral count data in label-free tandem mass spectrometry-based proteomicsQ33518240
Clinicopathologic correlations in a large Alzheimer disease center autopsy cohort: neuritic plaques and neurofibrillary tangles "do count" when staging disease severityQ34554590
Agrin in the CNS: a protein in search of a function?Q34828047
CSF markers for incipient Alzheimer's diseaseQ35541472
Changes in brain β-amyloid deposition and aquaporin 4 levels in response to altered agrin expression in miceQ35571874
Age and diagnostic performance of Alzheimer disease CSF biomarkers.Q35758640
Agrin is a major heparan sulfate proteoglycan accumulating in Alzheimer's disease brain.Q35787956
Transmembrane agrin regulates dendritic filopodia and synapse formation in mature hippocampal neuron culturesQ37308567
Comparison of the performance of two affinity depletion spin filters for quantitative proteomics of CSF: Evaluation of sensitivity and reproducibility of CSF analysis using GeLC-MS/MS and spectral countingQ38465617
The natural history of Alzheimer's disease. Description of study cohort and accuracy of diagnosisQ40759751
CSF biomarker levels in early and late onset Alzheimer's diseaseQ46652052
Alzheimer's disease can be accurately diagnosed in very mildly impaired individualsQ46814740
Synapse loss in cortex of agrin-deficient mice after genetic rescue of perinatal death.Q48115828
CSF Abeta 42 levels correlate with amyloid-neuropathology in a population-based autopsy studyQ48381623
CSF phosphorylated tau protein correlates with neocortical neurofibrillary pathology in Alzheimer's diseaseQ48408159
Accumulation of heparan sulfate proteoglycans in cerebellar senile plaquesQ48606558
Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severityQ48983820
Optimizing patient care and research: the Amsterdam Dementia Cohort.Q50712172
Clinical validity of Braak neuropathological staging in the oldest-oldQ53234837
Agrin and microvascular damage in Alzheimer’s diseaseQ60145604
Loss of synaptophysin-like immunoreactivity in the hippocampal formation is an early phenomenon in Alzheimer's diseaseQ72119373
P433issue1
P921main subjectbiomarkerQ864574
Alzheimer's diseaseQ11081
cerebrospinal fluidQ54196
P304page(s)75-80
P577publication date2015-03-29
P1433published inAlzheimer's & dementia (Amsterdam, Netherlands)Q27726390
P1476titleCan agrin cerebrospinal fluid concentration be used as an early biomarker for Alzheimer's disease?
P478volume1

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