Global gene expression profiling displays a network of dysregulated genes in non-atherosclerotic arterial tissue from patients with type 2 diabetes

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Global gene expression profiling displays a network of dysregulated genes in non-atherosclerotic arterial tissue from patients with type 2 diabetes is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1000831768
P356DOI10.1186/1475-2840-11-15
P932PMC publication ID3348024
P698PubMed publication ID22340758
P5875ResearchGate publication ID221838352

P50authorLars M RasmussenQ46237462
P2093author name stringSteen Knudsen
Vibe Skov
Malene Olesen
Maria L Hansen
P2860cites workAccelerated arterial stiffening and gene expression profile of the aorta in patients with coronary artery diseaseQ58034846
Increased Atherosclerotic Lesion Calcification in a Novel Mouse Model Combining Insulin Resistance, Hyperglycemia, and HypercholesterolemiaQ59703596
Matrix metalloproteinase-2 and -9 exacerbate arterial stiffening and angiogenesis in diabetes and chronic kidney diseaseQ62079386
A quantitative study of peripheral arterial calcification and glucose tolerance in elderly diabetics and non-diabeticsQ70664714
Development of vascular lesions in insulin-treated animals fed a normal dietQ71570310
The role of glycation cross-links in diabetic vascular stiffeningQ71657485
Glycosaminoglycans in the human aorta in diabetes mellitus: a study of tunica media from areas with and without atherosclerotic plaqueQ72401496
Aortic collagen alterations in human diabetes mellitus. Changes in basement membrane collagen content and in the susceptibility of total collagen to cyanogen bromide solubilisationQ72788318
Under control of the Ren-1c promoter, locally produced transforming growth factor-beta1 induces accumulation of glomerular extracellular matrix in transgenic miceQ77804955
Endothelial adhesion molecule expression is enhanced in the aorta and internal mammary artery of diabetic patientsQ78050013
Human vascular smooth muscle cells from diabetic patients are resistant to induced apoptosis due to high Bcl-2 expressionQ83214116
Saturated fatty acids do not directly stimulate Toll-like receptor signalingQ84365640
The innate immune system and diabetes mellitus: the relevance of periodontitis? A hypothesisQ84660130
Cytoscape: a software environment for integrated models of biomolecular interaction networksQ24515682
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profilesQ24536351
Kidney transplant rejection and tissue injury by gene profiling of biopsies and peripheral blood lymphocytesQ24675073
MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray dataQ24804397
Network biology: understanding the cell's functional organizationQ27861027
Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) ratsQ33857313
Endothelial dysfunction in diabetes.Q33959485
Microalbuminuria, endothelial dysfunction and cardiovascular riskQ33988945
Whole genome microarray analysis of growth hormone-induced gene expression in bone: T-box3, a novel transcription factor, regulates osteoblast proliferationQ34399090
Enhanced inflammatory responses to toll-like receptor 2/4 stimulation in type 1 diabetic coronary artery endothelial cells: the effect of insulinQ34478178
Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null miceQ34485920
Transcriptome analysis of human diabetic kidney diseaseQ35180096
Mediators of diabetic renal disease: the case for tgf-Beta as the major mediatorQ35611125
Role of insulin resistance and hyperglycemia in the development of atherosclerosisQ36738677
Atherosclerosis in diabetes and insulin resistanceQ36857541
Diabetes and diabetes-associated lipid abnormalities have distinct effects on initiation and progression of atherosclerotic lesionsQ37486465
Fibulin-1 is a marker for arterial extracellular matrix alterations in type 2 diabetesQ38331814
Gene expression profiling in glomeruli from human kidneys with diabetic nephropathy.Q38343234
Gene expression profiling of pulpal tissue reveals the molecular complexity of dental caries.Q38520492
Why does diabetes increase atherosclerosis? I don't know!Q39951404
Medial artery calcification. A neglected harbinger of cardiovascular complications in non-insulin-dependent diabetes mellitusQ40933115
Production of hyaluronan and chondroitin sulphate proteoglycans from human arterial smooth muscle--the effect of glucose, insulin, IGF-I or growth hormoneQ43675088
Insulin therapy improves insulin-stimulated endothelial function in patients with type 2 diabetes and ischemic heart diseaseQ43778816
Microarray profiling of human skeletal muscle reveals that insulin regulates approximately 800 genes during a hyperinsulinemic clampQ44350668
Diabetes and Glucose Tolerance as Risk Factors for Cardiovascular Disease: The Framingham StudyQ44680472
Arterial osteoprotegerin: increased amounts in diabetes and modifiable synthesis from vascular smooth muscle cells by insulin and TNF-alpha.Q45256838
Increased aortic stiffness in the insulin-resistant Zucker fa/fa rat.Q53860774
Insulin and atherosclerosis.Q54021059
Diabetes and periodontal disease: a case-control study.Q54667717
Increased Matrix Metalloproteinase 2 Activity in the Human Internal Mammary Artery Is Associated with Ageing, Hypertension, Diabetes and Kidney DysfunctionQ57913958
P4510describes a project that usesCytoscapeQ3699942
limmaQ112236343
P407language of work or nameEnglishQ1860
P921main subjecttype 2 diabetesQ3025883
atherosclerosisQ12252367
P304page(s)15
P577publication date2012-02-17
P1433published inCardiovascular DiabetologyQ2468083
P1476titleGlobal gene expression profiling displays a network of dysregulated genes in non-atherosclerotic arterial tissue from patients with type 2 diabetes
P478volume11

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cites work (P2860)
Q64062301A Comprehensive Survey of Tools and Software for Active Subnetwork Identification
Q36288862Alterations of specific biomarkers of metabolic pathways in vascular tree from patients with Type 2 diabetes
Q48444509AlzBase: an Integrative Database for Gene Dysregulation in Alzheimer's Disease
Q37297560Analysis of gene expression profile identifies potential biomarkers for atherosclerosis
Q55047354Diabetes adversely affects phospholipid profiles in human carotid artery endarterectomy plaques.
Q34419372Downregulation of type II diabetes mellitus and maturity onset diabetes of young pathways in human pancreatic islets from hyperglycemic donors.
Q36244494Galectin-3 and fibulin-1 in systolic heart failure - relation to glucose metabolism and left ventricular contractile reserve
Q36937435High glucose induces upregulation of scavenger receptors and promotes maturation of dendritic cells
Q48114716Is cardiovascular disease in patients with diabetes associated with serum levels of MMP-2, LOX, and the elastin degradation products ELM and ELM-2?
Q59489139Low-dose spironolactone reduces plasma fibulin-1 levels in patients with type 2 diabetes and resistant hypertension
Q36691127Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats
Q47328605Microarray analysis reveals gene and microRNA signatures in diabetic kidney disease
Q55071518No detectable differential microRNA expression between non-atherosclerotic arteries of type 2 diabetic patients (treated or untreated with metformin) and non-diabetic patients.
Q46714296Resveratrol regulates oxidative biomarkers and antioxidant enzymes in the brain of streptozotocin-induced diabetic rats
Q34306963Systems analysis of oxidant stress in the vasculature
Q37628285Tissue Non-Specific Genes and Pathways Associated with Diabetes: An Expression Meta-Analysis

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