Adenoviral-mediated expression of G2019S LRRK2 induces striatal pathology in a kinase-dependent manner in a rat model of Parkinson's disease.

scientific article published on 28 February 2015

Adenoviral-mediated expression of G2019S LRRK2 induces striatal pathology in a kinase-dependent manner in a rat model of Parkinson's disease. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.NBD.2015.02.019
P698PubMed publication ID25731749

P50authorBernard L. SchneiderQ37377455
Elpida TsikaQ56670281
Julien DusonchetQ64856197
Darren J MooreQ87693446
P2093author name stringPhilippe Colin
An Phu Tran Nguyen
P2860cites workDefective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosisQ24306886
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processingQ24597817
P921main subjectParkinson's diseaseQ11085
pathologyQ7208
striatumQ1319792
AdenoviridaeQ193447
P304page(s)49-61
P577publication date2015-02-28
P1433published inNeurobiology of DiseaseQ15716606
P1476titleAdenoviral-mediated expression of G2019S LRRK2 induces striatal pathology in a kinase-dependent manner in a rat model of Parkinson's disease
P478volume77

Reverse relations

cites work (P2860)
Q57143848Animal models of neurodegenerative diseases
Q91741105CAV-2-Mediated GFP and LRRK2G2019S Expression in the Macaca fascicularis Brain
Q64866880Genetic Modifiers of Neurodegeneration in a Drosophila Model of Parkinson's Disease
Q51082143Interaction of LRRK2 and α-Synuclein in Parkinson's Disease
Q98177378LRRK2 and Protein Aggregation in Parkinson's Disease: Insights From Animal Models
Q97066874LRRK2 and α-Synuclein: Distinct or Synergistic Players in Parkinson's Disease?
Q28078899LRRK2 inhibitors and their potential in the treatment of Parkinson's disease: current perspectives
Q39137358Mechanisms of LRRK2-dependent neurodegeneration: role of enzymatic activity and protein aggregation.
Q48239635Mechanisms of Mutant LRRK2 Neurodegeneration
Q39206443Models of LRRK2-Associated Parkinson's Disease
Q36379938Neurite Aggregation and Calcium Dysfunction in iPSC-Derived Sensory Neurons with Parkinson's Disease-Related LRRK2 G2019S Mutation.
Q48502440New developments in genetic rat models of Parkinson's disease
Q99716681Pathogenic LRRK2 requires secondary factors to induce cellular toxicity
Q39263032Targeting LRRK2 in Parkinson's disease: an update on recent developments
Q64864674The G2019S mutation in LRRK2 imparts resiliency to kinase inhibition
Q39206431Understanding the GTPase Activity of LRRK2: Regulation, Function, and Neurotoxicity.

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