Thapsigargin activates univalent- and bivalent-cation entry in human neutrophils by a SK&F I3 96365- and Gd3+-sensitive pathway and is a partial secretagogue: involvement of pertussis-toxin-sensitive G-proteins and protein phosphatases 1/2A and 2B i

scientific article published on March 1996

Thapsigargin activates univalent- and bivalent-cation entry in human neutrophils by a SK&F I3 96365- and Gd3+-sensitive pathway and is a partial secretagogue: involvement of pertussis-toxin-sensitive G-proteins and protein phosphatases 1/2A and 2B i is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1042/BJ3140679
P932PMC publication ID1217100
P698PubMed publication ID8670085
P5875ResearchGate publication ID14531451

P50authorIan F. MusgraveQ42211241
P2093author name stringR Seifert
K Wenzel-Seifert
D Krautwurst
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The class III antiarrhythmic drug amiodarone directly activates pertussis toxin-sensitive G proteins.Q40995304
The H1 receptor agonist 2-(3-chlorophenyl)histamine activates Gi proteins in HL-60 cells through a mechanism that is independent of known histamine receptor subtypes.Q41038945
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Lipophilic beta-adrenoceptor antagonists and local anesthetics are effective direct activators of G-proteinsQ41467494
The regulation of store-dependent Ca2+ influx in HL-60 granulocytes involves GTP-sensitive elementsQ41509037
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Thapsigargin inhibits Ca2+ entry into human neutrophil granulocytesQ42823404
Inhibition of L-type calcium-channel activity by thapsigargin and 2,5-t-butylhydroquinone, but not by cyclopiazonic acidQ42828701
Chemotactic peptide down-regulation of calcium mobilization induced by platelet-activating factor and by leukotriene B4 in human neutrophils is uncovered by protein phosphatase inhibitorsQ42829659
Characterization of receptor-mediated and store-regulated Ca2+ influx in human neutrophils.Q42832820
Lack of effect of opioid peptides, morphine and naloxone on superoxide formation in human neutrophils and HL-60 leukemic cellsQ44340390
Use of manganese to discriminate between calcium influx and mobilization from internal stores in stimulated human neutrophils.Q44789184
Differential inhibition of human neutrophil activation by cyclosporins A, D, and H. Cyclosporin H is a potent and effective inhibitor of formyl peptide-induced superoxide formationQ45296977
Uptake and intracellular sequestration of divalent cations in resting and methacholine-stimulated mouse lacrimal acinar cells. Dissociation by Sr2+ and Ba2+ of agonist-stimulated divalent cation entry from the refilling of the agonist-sensitive intrQ45971523
Characterization of the plasma membrane bound GTPase from rabbit neutrophils. I. Evidence for an Ni-like protein coupled to the formyl peptide, C5a, and leukotriene B4 chemotaxis receptorsQ46874581
Degradation of a calcium influx factor (CIF) can be blocked by phosphatase inhibitors or chelation of Ca2+.Q49069256
Partial inhibition of human neutrophil activation by FK-506 at supratherapeutic concentrationsQ53022050
Okadaic acid uncouples calcium entry from depletion of intracellular stores.Q53022473
The roles of extracellular and intracellular calcium in lysosomal enzyme release and superoxide anion generation by human neutrophilsQ57731264
Subcellular localization of Gi alpha in human neutrophilsQ57908518
Replenishing the storesQ59076136
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Arachidonate and other fatty acids mobilize Ca2+ ions and stimulate beta-glucuronidase release in a Ca(2+)-dependent fashion from undifferentiated HL-60 cellsQ70787077
Differential distribution of neuronal markers and neuropeptides in the human lacrimal glandQ71885199
Novel potent inhibitor of receptor-activated nonselective cation currents in HL-60 cellsQ72082143
Phosphorylation down-regulates the store-operated Ca2+ entry pathway of human neutrophilsQ72772757
Activation by chemotactic peptide of a receptor-operated Ca2+ entry pathway in differentiated HL60 cellsQ72809134
Cyclosporin H is a potent and selective formyl peptide receptor antagonist. Comparison with N-t-butoxycarbonyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L- leucyl-L-phenylalanine and cyclosporins A, B, C, D, and EQ72967745
P407language of work or nameEnglishQ1860
P304page(s)679-686
P577publication date1996-03-01
P1433published inBiochemical JournalQ864221
P1476titleThapsigargin activates univalent- and bivalent-cation entry in human neutrophils by a SK&F I3 96365- and Gd3+-sensitive pathway and is a partial secretagogue: involvement of pertussis-toxin-sensitive G-proteins and protein phosphatases 1/2A and 2B in the signal-transduction pathway
P478volume314 ( Pt 2)

Reverse relations

cites work (P2860)
Q424701522-Benzyloxybenzaldehyde inhibits formyl peptide-stimulated increase in intracellular Ca2+ in neutrophils mainly by blocking Ca2+ entry.
Q46630908A store-operated nonselective cation channel in human lymphocytes
Q27313547Calpain 2 controls turnover of LFA-1 adhesions on migrating T lymphocytes
Q44466208Characterization of maleimide-activated Ca2+ entry in neutrophils
Q43882504Cholesterol-modulating agents selectively inhibit calcium influx induced by chemoattractants in human neutrophils
Q44264306GEA3162 stimulates Ca2+ entry in neutrophils
Q41010992High constitutive activity of the human formyl peptide receptor
Q43733608Inhibition of extracellular Ca(2+) entry by YC-1, an activator of soluble guanylyl cyclase, through a cyclic GMP-independent pathway in rat neutrophils
Q73375412Inhibition of interleukin-8-activated human neutrophil chemotaxis by thapsigargin in a calcium- and cyclic AMP-dependent way
Q73396326Inhibition of store-dependent capacitative Ca2+ influx by unsaturated fatty acids
Q33406546Intracellular free calcium mediates glioma cell detachment and cytotoxicity after photodynamic therapy
Q42837762LFA-1-mediated adhesion is regulated by cytoskeletal restraint and by a Ca2+-dependent protease, calpain
Q77587549Protein phosphatase inhibitors exert specific and nonspecific effects on calcium influx in thapsigargin-treated human neutrophils
Q45159213Stimulation of cellular free Ca2+ elevation and inhibition of store-operated Ca2+ entry by kazinol B in neutrophils
Q46651587The immunostimulatory peptide WKYMVm-NH activates bone marrow mouse neutrophils via multiple signal transduction pathways

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