PBX/extradenticle is required to re-establish axial structures and polarity during planarian regeneration.

scientific article published on 14 January 2013

PBX/extradenticle is required to re-establish axial structures and polarity during planarian regeneration. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1242/DEV.082982
P932PMC publication ID3557773
P698PubMed publication ID23318635
P5875ResearchGate publication ID234133640

P50authorAziz A. AboobakerQ54206627
P2093author name stringDaniel A Felix
Belen Tejada-Romero
Robert A Blassberg
P2860cites workThe subcellular localization of PBX1 and EXD proteins depends on nuclear import and export signals and is modulated by association with PREP1 and HTHQ24605482
Combining classical and molecular approaches elaborates on the complexity of mechanisms underpinning anterior regenerationQ27312105
SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planariansQ27334311
dlx and sp6-9 Control optic cup regeneration in a prototypic eyeQ27338145
The TALE class homeobox gene Smed-prep defines the anterior compartment for head regenerationQ27347706
Planarian Hh signaling regulates regeneration polarity and links Hh pathway evolution to ciliaQ30494271
Smed-Evi/Wntless is required for beta-catenin-dependent and -independent processes during planarian regeneration.Q51826212
Silencing of Smed-betacatenin1 generates radial-like hypercephalized planarians.Q51963787
Planarian homologs of netrin and netrin receptor are required for proper regeneration of the central nervous system and the maintenance of nervous system architecture.Q52043748
An in situ hybridization protocol for planarian embryos: monitoring myosin heavy chain gene expression.Q52044695
Regeneration and pattern formation in planarians. I. The pattern of mitosis in anterior and posterior regeneration in Dugesia (G) tigrina, and a new proposal for blastema formationQ70677689
Smed-betacatenin-1 is required for anteroposterior blastema polarity in planarian regenerationQ80156777
The maintenance and regeneration of the planarian excretory system are regulated by EGFR signalingQ30503349
Planarian Hedgehog/Patched establishes anterior-posterior polarity by regulating Wnt signalingQ33564284
Segment-specific neuronal subtype specification by the integration of anteroposterior and temporal cuesQ33582048
A dual platform approach to transcript discovery for the planarian Schmidtea mediterranea to establish RNAseq for stem cell and regeneration biologyQ33778543
Expression of secreted Wnt pathway components reveals unexpected complexity of the planarian amputation responseQ34131150
Planarian stem cells: a simple paradigm for regeneration.Q34167037
Clonogenic neoblasts are pluripotent adult stem cells that underlie planarian regenerationQ34184695
The Meis homeoprotein regulates the axolotl Prod 1 promoter during limb regenerationQ34193660
Telomere maintenance and telomerase activity are differentially regulated in asexual and sexual wormsQ34257327
The Drosophila Extradenticle and Homothorax selector proteins control branchless/FGF expression in mesodermal bridge-cellsQ34360433
Gene expression of pluripotency determinants is conserved between mammalian and planarian stem cells.Q36049563
Double-stranded RNA specifically disrupts gene expression during planarian regenerationQ36336691
Stem cell-based growth, regeneration, and remodeling of the planarian intestineQ36375720
Hox and Pbx factors control retinoic acid synthesis during hindbrain segmentation.Q36916855
A wound-induced Wnt expression program controls planarian regeneration polarity.Q37346221
Pbx homeodomain proteins: TALEnted regulators of limb patterning and outgrowthQ37854540
Proximodistal identity during vertebrate limb regeneration is regulated by Meis homeodomain proteinsQ38322021
A regulatory program for excretory system regeneration in planariansQ38536413
Organizing the DV axis during planarian regeneration.Q38577542
Competition for cofactor-dependent DNA binding underlies Hox phenotypic suppressionQ39332108
The Mi-2-like Smed-CHD4 gene is required for stem cell differentiation in the planarian Schmidtea mediterraneaQ39849555
Spoltud-1 is a chromatoid body component required for planarian long-term stem cell self-renewalQ41780026
A comparative transcriptomic analysis reveals conserved features of stem cell pluripotency in planarians and mammalsQ41829171
Genetic regulators of a pluripotent adult stem cell system in planarians identified by RNAi and clonal analysisQ41896125
Molecular analysis of stem cells and their descendants during cell turnover and regeneration in the planarian Schmidtea mediterraneaQ41922401
Molecular patterning mechanism underlying metamorphosis of the thoracic leg in Manduca sextaQ42033816
Defining the molecular profile of planarian pluripotent stem cells using a combinatorial RNAseq, RNA interference and irradiation approach.Q42113314
Regeneration and maintenance of the planarian midline is regulated by a slit orthologue.Q42123378
Beta-catenin defines head versus tail identity during planarian regeneration and homeostasisQ42142686
A Bmp/Admp regulatory circuit controls maintenance and regeneration of dorsal-ventral polarity in planariansQ42239465
Planarian regeneration involves distinct stem cell responses to wounds and tissue absenceQ42413468
Polarized notum activation at wounds inhibits Wnt function to promote planarian head regenerationQ42555211
Expression of homothorax and extradenticle mRNA in the legs of the crustacean Parhyale hawaiensis: evidence for a reversal of gene expression regulation in the pancrustacean lineageQ42559998
Morphogenesis defects are associated with abnormal nervous system regeneration following roboA RNAi in planariansQ42610077
Conserved regulation of proximodistal limb axis development by Meis1/HthQ42807847
Mutations in the Drosophila gene extradenticle affect the way specific homeo domain proteins regulate segmental identityQ44066543
Diverse miRNA spatial expression patterns suggest important roles in homeostasis and regeneration in planarians.Q44656131
The roles of two C. elegans HOX co-factor orthologs in cell migration and vulva developmentQ46497333
Roles of the Homothorax/Meis/Prep homolog UNC-62 and the Exd/Pbx homologs CEH-20 and CEH-40 in C. elegans embryogenesis.Q47069472
Antagonism between extradenticle function and Hedgehog signalling in the developing limbQ47814820
A Bruno-like gene is required for stem cell maintenance in planariansQ48085602
FGFR-related gene nou-darake restricts brain tissues to the head region of planariansQ48278854
A planarian orthopedia homolog is specifically expressed in the branch region of both the mature and regenerating brainQ48516867
Early planarian brain regeneration is independent of blastema polarity mediated by the Wnt/β-catenin pathway.Q48972335
P4510describes a project that usesImageJQ1659584
P433issue4
P407language of work or nameEnglishQ1860
P1104number of pages10
P304page(s)730-739
P577publication date2013-01-14
P1433published inDevelopmentQ3025404
P1476titlePBX/extradenticle is required to re-establish axial structures and polarity during planarian regeneration
P478volume140

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cites work (P2860)
Q92060135'Building a perfect body': control of vertebrate organogenesis by PBX-dependent regulatory networks
Q27318464A forkhead transcription factor is wound-induced at the planarian midline and required for anterior pole regeneration
Q35945586Comparative analysis of Wnt expression identifies a highly conserved developmental transition in flatworms.
Q30946349Digital gene expression approach over multiple RNA-Seq data sets to detect neoblast transcriptional changes in Schmidtea mediterranea
Q37144523Forkhead containing transcription factor Albino controls tetrapyrrole-based body pigmentation in planarian
Q59137018Genome-wide transcriptome profiling and spatial expression analyses identify signals and switches of development in tapeworms
Q28073913Go ahead, grow a head! A planarian's guide to anterior regeneration
Q48306920Integrin suppresses neurogenesis and regulates brain tissue assembly in planarian regeneration.
Q40848483JNK signalling is necessary for a Wnt- and stem cell-dependent regeneration programme.
Q88107247Neoblast-enriched zinc finger protein FIR1 triggers local proliferation during planarian regeneration
Q64283461Nuclear receptor NR4A is required for patterning at the ends of the planarian anterior-posterior axis
Q38810344PHRED-1 is a divergent neurexin-1 homolog that organizes muscle fibers and patterns organs during regeneration
Q36974686Physiological controls of large-scale patterning in planarian regeneration: a molecular and computational perspective on growth and form
Q43500590Reactivating head regrowth in a regeneration-deficient planarian species
Q35769230Reactive Oxygen Species in Planarian Regeneration: An Upstream Necessity for Correct Patterning and Brain Formation.
Q43929265Stem cell-dependent formation of a functional anterior regeneration pole in planarians requires Zic and Forkhead transcription factors.
Q57025286The Cellular and Molecular Basis for Planarian Regeneration
Q41949115The miR-124 family of microRNAs is crucial for regeneration of the brain and visual system in the planarian Schmidtea mediterranea
Q36236909Types or States? Cellular Dynamics and Regenerative Potential
Q41483639Wnt, Ptk7, and FGFRL expression gradients control trunk positional identity in planarian regeneration
Q35178918teashirt is required for head-versus-tail regeneration polarity in planarians.
Q27315030zic-1 Expression in Planarian neoblasts after injury controls anterior pole regeneration