The biochemical analysis of methadone modulation on morphine-induced tolerance and dependence in the rat brain

scientific article published on 15 March 2007

The biochemical analysis of methadone modulation on morphine-induced tolerance and dependence in the rat brain is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1159/000100893
P698PubMed publication ID17356311

P2093author name stringLi He
Jennifer L Whistler
P2860cites workEssential role for RGS9 in opiate actionQ24655663
Activation of mu-opioid receptors transfers control of Galpha subunits to the regulator of G-protein signaling RGS9-2: role in receptor desensitizationQ28301079
Morphine promotes rapid, arrestin-dependent endocytosis of mu-opioid receptors in striatal neuronsQ28575335
Functional dissociation of mu opioid receptor signaling and endocytosis: implications for the biology of opiate tolerance and addiction.Q33873664
Endocytosis of the mu opioid receptor reduces tolerance and a cellular hallmark of opiate withdrawalQ34104454
Regulation of opioid receptor trafficking and morphine tolerance by receptor oligomerizationQ34113042
Regulated endocytosis of opioid receptors: cellular mechanisms and proposed roles in physiological adaptation to opiate drugsQ35172820
Morphine-activated opioid receptors elude desensitization by beta-arrestinQ36280218
Role for G protein-coupled receptor kinase in agonist-specific regulation of mu-opioid receptor responsivenessQ36514037
Sequestration of the delta opioid receptor. Role of the C terminus in agonist-mediated internalizationQ37377196
Receptor endocytosis counteracts the development of opioid toleranceQ40505684
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor geneQ41157124
Agonist-induced mu opioid receptor phosphorylation and functional desensitization in rat thalamusQ42502880
Molecular components of tolerance to opiates in single hippocampal neuronsQ43830208
Effects of morphine withdrawal on micro-opioid receptor-stimulated guanylyl 5'-[gamma-[35S]thio]-triphosphate autoradiography in rat brainQ44050763
The effect of intrinsic efficacy on opioid toleranceQ44334928
Modulation of opioid analgesia, tolerance and dependence by Gs-coupled, GM1 ganglioside-regulated opioid receptor functionsQ44350368
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)193-202
P577publication date2007-03-15
P1433published inPharmacologyQ15759653
P1476titleThe biochemical analysis of methadone modulation on morphine-induced tolerance and dependence in the rat brain
P478volume79

Reverse relations

cites work (P2860)
Q33908225Chronic ethanol consumption in rats produces opioid antinociceptive tolerance through inhibition of mu opioid receptor endocytosis
Q34144947How to design an opioid drug that causes reduced tolerance and dependence
Q27006957Kir3 channel signaling complexes: focus on opioid receptor signaling
Q34187516Methadone antinociception is dependent on peripheral opioid receptors