Effects of alpha-difluoromethylornithine on protein synthesis and synthesis of the variant-specific glycoprotein (VSG) in Trypanosoma brucei brucei

scientific article

Effects of alpha-difluoromethylornithine on protein synthesis and synthesis of the variant-specific glycoprotein (VSG) in Trypanosoma brucei brucei is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1042/BJ2500295
P932PMC publication ID1148847
P698PubMed publication ID3128277
P5875ResearchGate publication ID20028565

P2093author name stringMcCann PP
Cross-Doersen DE
Bitonti AJ
P2860cites workCleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
Polyamine metabolism and functionQ34270606
Decreased protein-synthetic activity is an early consequence of spermidine depletion in rat hepatoma tissue-culture cellsQ42867844
Polyamine depletion following exposure to DL-alpha-difluoromethylornithine both in vivo and in vitro initiates morphological alterations and mitochondrial activation in a monomorphic strain of Trypanosoma brucei bruceiQ44045347
Antigenic variation in trypanosomesQ44562876
Inhibition of polyamine biosynthesis by alpha-difluoromethylornithine in African trypanosomes and Pneumocystis carinii as a basis of chemotherapy: biochemical and clinical aspectsQ44885515
Antagonism by polyamines of the curative effects of alpha-difluoromethylornithine in Trypanosoma brucei brucei infectionsQ45213862
Difiuoromethylornithine in the treatment of African trypanosomiasisQ46255411
Role of antibody in the elimination of trypanosomes after DL-alpha-difluoromethylornithine chemotherapy.Q46709382
Isolation of salivarian trypanosomes from man and other mammals using DEAE-cellulose.Q52487021
In vivo effects of alpha-DL-difluoromethylornithine on the metabolism and morphology of Trypanosoma brucei brucei.Q52499094
Inhibition of Trypanosoma brucei brucei peptidyl transferase activity by sparsomycin analogs and effects on trypanosome protein synthesis and proliferation.Q53897805
Necessity of antibody response in the treatment of African trypanosomiasis with alpha-difluoromethylornithineQ58846432
Polyamine metabolism: a potential therapeutic target in trypanosomesQ58847872
In vivo effects of difluoromethylornithine on trypanothione and polyamine levels in bloodstream forms of Trypanosoma bruceiQ58850283
Antigenic variation in African trypanosomesQ69916598
In Vitro Cultivation of Bloodstream Forms of Trypanosoma brucei, T. rhodesiense, and T. gambiense1Q71046738
On The Surface Coat and Flagellar Adhesion in TrypanosomesQ71242215
Myristylation of the membrane form of a Trypanosoma brucei variant surface glycoproteinQ71275814
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectTrypanosoma bruceiQ33244
P1104number of pages4
P304page(s)295-298
P577publication date1988-02-01
P1433published inBiochemical JournalQ864221
P1476titleEffects of alpha-difluoromethylornithine on protein synthesis and synthesis of the variant-specific glycoprotein (VSG) in Trypanosoma brucei brucei
P478volume250

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cites work (P2860)
Q52180765Changes in polysome profiles accompany trypanosome development.
Q35268274Cure of Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense infections in mice with an irreversible inhibitor of S-adenosylmethionine decarboxylase
Q35262080Differential susceptibility to DL-alpha-difluoromethylornithine in clinical isolates of Trypanosoma brucei rhodesiense
Q38232788Eflornithine. A new drug in the treatment of sleeping sickness
Q35224465Interactions between immunity and chemotherapy in the treatment of the trypanosomiases and leishmaniases
Q38715992Novel biochemical pathways in parasitic protozoa
Q28732919Polyamine homoeostasis as a drug target in pathogenic protozoa: peculiarities and possibilities
Q34460309Sulfur-containing amino acid metabolism in parasitic protozoa
Q53979361The upstream open reading frame of the mRNA encoding S-adenosylmethionine decarboxylase is a polyamine-responsive translational control element.

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