Thomas B. Kepler

researcher

Thomas B. Kepler is …
instance of (P31):
humanQ5

External links are
P1960Google Scholar author IDqVl73CAAAAAJ
P549Mathematics Genealogy Project ID52798
P4955MR Author ID259955
P496ORCID iD0000-0002-1383-6865
P1153Scopus author ID7004537298
P1556zbMATH author IDkepler.thomas-b

P184doctoral advisorLarry AbbottQ19938073
P185doctoral studentMichael D. RadmacherQ102222513
Lindsay Grey CowellQ102252333
P69educated atBrandeis UniversityQ49119
P108employerBoston University School of MedicineQ4119659
P734family nameKeplerQ16277846
KeplerQ16277846
KeplerQ16277846
P735given nameBuddQ16274762
BuddQ16274762
ThomasQ16428906
ThomasQ16428906
P6104maintained by WikiProjectWikiProject MathematicsQ8487137
P106occupationmicrobiologistQ3779582
neuroscientistQ6337803
P21sex or gendermaleQ6581097

Reverse relations

doctoral advisor (P184)
Q102252333Lindsay Grey Cowell
Q102222513Michael D. Radmacher

author (P50)
Q58045295A Bayesian approach for estimating calibration curves and unknown concentrations in immunoassays
Q42027962A Bayesian approach for estimating calibration curves and unknown concentrations in immunoassays
Q58045346A linear two-state model with complex dynamics
Q41877244A model for migratory B cell oscillations from receptor down-regulation induced by external chemokine fields
Q33952210A two-tiered model for simulating the ecological and evolutionary dynamics of rapidly evolving viruses, with an application to influenza
Q34207773Advantage of rare HLA supertype in HIV disease progression
Q27684503Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains
Q37363517Amino Acid Changes in the HIV-1 gp41 Membrane Proximal Region Control Virus Neutralization Sensitivity
Q42184951Amino acid biophysical properties in the statistical prediction of peptide-MHC class I binding.
Q37680009An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1.
Q47824025An information-theoretic method for the treatment of plural ancestry in phylogenetics.
Q35382871Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors
Q35487441Analysis of immunoglobulin transcripts and hypermutation following SHIV(AD8) infection and protein-plus-adjuvant immunization
Q35073270Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved
Q34273373B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study
Q58045299Bayesian Spatio-Dynamic Modeling in Cell Motility Studies: Learning Nonlinear Taxic Fields Guiding the Immune Response
Q36290038Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial.
Q27671619Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin
Q33642157Chiropteran types I and II interferon genes inferred from genome sequencing traces by a statistical gene-family assembler
Q36491949Classification of osteoarthritis biomarkers: a proposed approach.
Q27644501Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
Q37107609Comparison of multiple vaccine vectors in a single heterologous prime-boost trial
Q34114798Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies
Q91605118Correction: Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies
Q44869273Density-dependent prenatal androgen exposure as an endogenous mechanism for the generation of cycles in small mammal populations
Q38959483Differential reactivity of germ line allelic variants of a broadly neutralizing HIV-1 antibody to a gp41 fusion intermediate conformation
Q47213776Diversification of Ig superfamily genes in an invertebrate
Q36312295Drug concentration heterogeneity facilitates the evolution of drug resistance.
Q44850209Enhanced evolvability in immunoglobulin V genes under somatic hypermutation
Q34016211Envelope deglycosylation enhances antigenicity of HIV-1 gp41 epitopes for both broad neutralizing antibodies and their unmutated ancestor antibodies
Q28748487First qualification study of serum biomarkers as indicators of total body burden of osteoarthritis
Q36740992Flow: Statistics, visualization and informatics for flow cytometry
Q42073528Genetic correlates of autoreactivity and autoreactive potential in human Ig heavy chains
Q58045365Geometric phase shifts under adiabatic parameter changes in classical dissipative systems
Q28743596H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination
Q38631751HIV DNA-Adenovirus Multiclade Envelope Vaccine Induces Gp41 Antibody Immunodominance in Rhesus Macaques
Q40449984HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism.
Q35728947HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies
Q42939116High-throughput isolation of immunoglobulin genes from single human B cells and expression as monoclonal antibodies
Q45747345Human immunodeficiency virus type 1-specific cytotoxic T lymphocyte activity is inversely correlated with HIV type 1 viral load in HIV type 1-infected long-term survivors
Q34324992Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies
Q24815096Identifying differential expression in multiple SAGE libraries: an overdispersed log-linear model approach
Q30382955Immunogenic Stimulus for Germline Precursors of Antibodies that Engage the Influenza Hemagglutinin Receptor-Binding Site.
Q34177732Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies
Q44874966Improved inference of mutation rates: I. An integral representation for the Luria-Delbrück distribution
Q52067136Improved inference of mutation rates: II. Generalization of the Luria-Delbrück distribution for realistic cell-cycle time distributions.
Q33370669Improving peptide-MHC class I binding prediction for unbalanced datasets
Q60301098Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier
Q30395005Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain
Q35441583Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated
Q47118310Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations
Q37221575Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages
Q33664494Invertebrate immune systems--not homogeneous, not simple, not well understood
Q90503791Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields
Q34042758Isolation of a human anti-HIV gp41 membrane proximal region neutralizing antibody by antigen-specific single B cell sorting
Q41669208Key mutations stabilize antigen-binding conformation during affinity maturation of a broadly neutralizing influenza antibody lineage
Q42029789Large-scale analysis of human heavy chain V(D)J recombination patterns
Q53634878Longitudinal analysis of T-cell receptor variable beta chain repertoire in patients with acute graft-versus-host disease after allogeneic stem cell transplantation.
Q27644415Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody
Q51621282Measurement of cell migration on surface-bound fibronectin gradients.
Q33802408Metastasizing patent claims on BRCA1
Q40290511Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.
Q34323976Mixtures of Gaussian Wells: Theory, Computation, and Application
Q33958359Modeling and optimization of populations subject to time-dependent mutation
Q28572290Morphologic analysis correlates with gene expression changes in cultured F344 rat mesothelial cells
Q51985457Neonate-primed CD8+ memory cells rival adult-primed memory cells in antigen-driven expansion and anti-viral protection.
Q90135569Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies
Q29307029Open Source Research — the Power of Us
Q46847940P19-50. Simulation of an MPER peptide samples epitope conformations of two broadly neutralizing antibodies
Q51603839Paradoxical suppression of poly-specific broadly neutralizing antibodies in the presence of strain-specific neutralizing antibodies following HIV infection.
Q24814174Pathway level analysis of gene expression using singular value decomposition
Q44139795Patient socioeconomic status is an independent predictor of operative mortality
Q58045357Physiological Insights from Cellular and Network Models of the Stomatogastric Nervous System of Lobsters and Crabs
Q40092127Potent and broad HIV-neutralizing antibodies in memory B cells and plasma
Q27675207Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody
Q44870111Predicted and inferred waiting times for key mutations in the germinal centre reaction: evidence for stochasticity in selection
Q36370482Prospective estimation of recombination signal efficiency and identification of functional cryptic signals in the genome by statistical modeling
Q34892584Quantification of total T-cell receptor diversity by flow cytometry and spectratyping
Q44871622Quantitative evaluation of alternative mechanisms of blood and testes disposition of di(2-ethylhexyl) phthalate and mono(2-ethylhexyl) phthalate in rats
Q102210404Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth
Q38988188Reconstructing a B-Cell Clonal Lineage. II. Mutation, Selection, and Affinity Maturation
Q22337372Reduction of conductance-based neuron models
Q58045303Rejoinder
Q41910605Rescue of cytotoxic function in the CD8alpha knockout mouse by removal of MHC class II.
Q24678401Review of 54 patients with complete DiGeorge anomaly enrolled in protocols for thymus transplantation: outcome of 44 consecutive transplants
Q36738008Secretion of MIP-1β and MIP-1α by CD8(+) T-lymphocytes correlates with HIV-1 inhibition independent of coreceptor usage
Q30495004Selective and site-specific mobilization of dermal dendritic cells and Langerhans cells by Th1- and Th2-polarizing adjuvants
Q40118226Sequence intrinsic somatic mutation mechanisms contribute to affinity maturation of VRC01-class HIV-1 broadly neutralizing antibodies
Q58045331Similar CD19 Dysregulation in Two Autoantibody-Associated Autoimmune Diseases Suggests a Shared Mechanism of B-Cell Tolerance Loss
Q39783279SoDA2: a Hidden Markov Model approach for identification of immunoglobulin rearrangements
Q33229588SoDA: implementation of a 3D alignment algorithm for inference of antigen receptor recombinations
Q52390653Somatic hypermutation in B cells: an optimal control treatment.
Q30997115SpA: web-accessible spectratype analysis: data management, statistical analysis and visualization
Q30497163Spatial Mixture Modelling for Unobserved Point Processes: Examples in Immunofluorescence Histology
Q36762536Spatiotemporal programming of a simple inflammatory process
Q58045361Spike initiation and propagation on axons with slow inward currents
Q40290521Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.
Q30992040Statistical analysis of antigen receptor spectratype data
Q34420737Statistical inference of sequence-dependent mutation rates.
Q36446733Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site
Q40626878Structural analysis of the unmutated ancestor of the HIV-1 envelope V2 region antibody CH58 isolated from an RV144 vaccine efficacy trial vaccinee
Q33922778Surface plasmon resonance measurements of plasma antibody avidity during primary and secondary responses to anthrax protective antigen
Q47372228Terminal deoxynucleotidyl transferases from elasmobranchs reveal structural conservation within vertebrates
Q46690685The 185/333 gene family is a rapidly diversifying host-defense gene cluster in the purple sea urchin Strongylocentrotus purpuratus
Q36717764The Multiscale Systems Immunology project: software for cell-based immunological simulation
Q35132544The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling.
Q33466761The dynamics of T-cell receptor repertoire diversity following thymus transplantation for DiGeorge anomaly
Q33844333Toxin-coupled MHC class I tetramers can specifically ablate autoreactive CD8+ T cells and delay diabetes in nonobese diabetic mice
Q35868076Two distinct broadly neutralizing antibody specificities of different clonal lineages in a single HIV-1-infected donor: implications for vaccine design
Q31047702Unselected mutations in the human immunodeficiency virus type 1 genome are mostly nonsynonymous and often deleterious
Q33612459Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates
Q27675879Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2
Q40955071Viral receptor-binding site antibodies with diverse germline origins
Q40198060Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop
Q43548521Waiting times to appearance and dominance of advantageous mutants: estimation based on the likelihood
Q48831166beta cell-specific CD4+ T cell clonotypes in peripheral blood and the pancreatic islets are distinct

Q19938073Larry Abbottdoctoral studentP185

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