Serotonin receptor subtype mediation of the interoceptive discriminative stimuli induced by 5-methoxy-N,N-dimethyltryptamine

scientific article published on January 1987

Serotonin receptor subtype mediation of the interoceptive discriminative stimuli induced by 5-methoxy-N,N-dimethyltryptamine is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1053721406
P356DOI10.1007/BF00179927
P698PubMed publication ID3122248

P2093author name stringT Glaser
J Traber
D G Spencer
P2860cites workIdentification of presynaptic serotonin autoreceptors using a new ligand: 3H-PATQ48738976
Discriminative stimulus properties of the 5-HT1A agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH DPAT).Q52261135
Discriminative stimulus properties of quipazine: mediation by serotonin2 binding sites.Q52275732
DOM-stimulus generalization to LSD and other hallucinogenic indolealkylamines.Q52282914
Behavioral effects of 5-methoxy-N,N-dimethyltryptamine and dose-dependent antagonism by BC-105.Q52284566
Effects of 8-OH-DPAT, lisuride and some ergot-related compounds on the acoustic startle response in the ratQ67301107
Pharmacological analysis of the behavioural and thermoregulatory effects of the putative 5-HT1 receptor agonist, RU 24969, in the ratQ70151999
Effects of a new type of 5-HT receptor agonist on male rat sexual behaviorQ70561140
Antagonism of the effects of the hallucinogen DOM and the purported 5-HT agonist quipazine by 5-HT2 antagonistsQ71036856
Differential actions of serotonin antagonists on two behavioral models of serotonin receptor activation in the ratQ71262469
Discrimination of multiple [3H]5-hydroxytryptamine binding sites by the neuroleptic spiperone in rat brainQ71482384
Hallucinogenic agents as discriminative stimuli: a correlation with serotonin receptor affinitiesQ71522257
Buspirone: Action on serotonin receptors in calf hippocampusQ72553007
Differential effects of a new serotoninomimetic drug, 8-OH-DPAT, on copulatory behavior and pelvic thrusting pattern in the male ratQ72813683
Development of selective tolerance to the serotonin behavioral syndrome and suppression of locomotor activity after repeated administration of either 5-MeODMT or mCPPQ93580151
Receptor-binding properties in vitro and in vivo of ritanserin: A very potent and long acting serotonin-S2 antagonistQ28282022
Evidence for 5-HT2 involvement in the mechanism of action of hallucinogenic agentsQ34262666
Thermoregulatory responses to serotonin (5-HT) receptor stimulation in the rat. Evidence for opposing roles of 5-HT2 and 5-HT1A receptorsQ34562816
Characterization of the 5-hydroxytryptamine1a receptor-mediated inhibition of forskolin-stimulated adenylate cyclase activity in guinea pig and rat hippocampal membranesQ34683834
The stereoselectivity of serotonin uptake in brain tissue and blood platelets: the topography of the serotonin uptake areaQ39478261
The mechanism of action of fenfluramineQ40489566
Hallucinogens as a discriminative stimuli: Generalization of DOM to a 5-methoxy-N, N-dimethyltryptamine stimulusQ40596498
Subtypes of the 5-HT receptor mediating the behavioural responses to 5-methoxy-N,N-dimethyltryptamine in the rat.Q41352922
8-Hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) elicits eating in free-feeding rats by acting on central serotonin neuronsQ41353222
A behavioural and biochemical study in mice and rats of putative selective agonists and antagonists for 5-HT1 and 5-HT2 receptorsQ41740406
The 5-HT1 receptor agonist RU-24969 decreases 5-hydroxytryptamine (5-HT) release and metabolism in the rat frontal cortex in vitro and in vivoQ41786566
Possible 5-hydroxytryptamine1 (5-HT1) receptor involvement in the stimulus properties of 1-(m-trifluoromethylphenyl)piperazine (TFMPP).Q42018192
Molecular pharmacology of 5-HT1 and 5-HT2 recognition sites in rat and pig brain membranes: radioligand binding studies with [3H]5-HT, [3H]8-OH-DPAT, (-)[125I]iodocyanopindolol, [3H]mesulergine and [3H]ketanserinQ42203475
TFMPP may produce its stimulus effects via a 5-HT1B mechanismQ42226581
Autoradiographic identification and topographical analyses of high affinity serotonin receptor subtypes as a target for the novel putative anxiolytic TVX Q 7821.Q43755977
On the in vivo and in vitro actions of fenfluramine and its derivatives on central monoamine neurons, especially 5-hydroxytryptamine neurons, and their relation to the anorectic activity of fenfluramineQ44263723
Binding of the putative anxiolytic TVX Q 7821 to hippocampal 5-hydroxytryptamine (5-HT) recognition sitesQ44979498
Differential effects of 5-hydroxytryptamine1a selective drugs on the 5-HT behavioral syndromeQ45027380
Pharmacological differentiation and characterization of 5-HT1A, 5-HT1B, and 5-HT1C binding sites in rat frontal cortexQ45333608
Two distinct serotonin receptors: regional variations in receptor binding in mammalian brainQ46832632
Inhibition of forskolin-stimulated adenylate cyclase activity by 5-HT receptor agonistsQ46930255
[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.Q46980089
The interoceptive discriminative stimuli induced by the novel putative anxiolytic TVX Q 7821: behavioral evidence for the specific involvement of serotonin 5-HT1A receptorsQ48258329
Buspirone decreases the activity of serotonin-containing neurons in the dorsal raphe in freely-moving catsQ48284697
Ipsapirone depresses neuronal activity in the dorsal raphe nucleus and the hippocampal formationQ48288246
Neurochemical and behavioural evidence for mediation of the hyperphagic action of 8-OH-DPAT by 5-HT cell body autoreceptorsQ48289171
Inhibition of serotonergic dorsal raphe neurons by systemic and iontophoretic administration of buspirone, a non-benzodiazepine anxiolytic drugQ48299256
[125I]LSD labels 5-HT1C recognition sites in pig choroid plexus membranes. Comparison with [3H]mesulergine and [3H]5-HT bindingQ48299880
(-)-Propranolol blocks the inhibition of serotonergic dorsal raphe cell firing by 5-HT1A selective agonistsQ48300462
5-HT1A-receptors mediate stimulation of adenylate cyclase in rat hippocampusQ48318391
Pharmacological characterization of release-regulating serotonin autoreceptors in rat cerebellumQ48319635
Serotonin receptors in the human brain. II. Characterization and autoradiographic localization of 5-HT1C and 5-HT2 recognition sitesQ48332579
Differential pharmacology and function of two 5-HT1 receptors modulating transmitter release in rat cerebellumQ48352105
In vivo voltammetry in the suprachiasmatic nucleus of the rat: effects of RU24969, methiothepin and ketanserinQ48377699
The effects of a 5-HT1 receptor ligand isapirone (TVX Q 7821) on 5-HT synthesis and the behavioural effects of 5-HT agonists in mice and ratsQ48419501
Stereoselective blockade at the 5-HT autoreceptor and inhibition of radioligand binding to central 5-HT recognition sites by the optical isomers of methiothepinQ48419735
Identity of inhibitory presynaptic 5-hydroxytryptamine (5-HT) autoreceptors in the rat brain cortex with 5-HT1B binding sitesQ48419772
1-(2-Pyrimidinyl)-piperazine as active metabolite of buspirone in man and rat.Q48421321
[3H]DOB: a specific agonist radioligand for 5-HT2 serotonin receptorsQ48444198
Selective labeling of 5-HT1A and 5-HT1B binding sites in bovine brainQ48451948
Presynaptic 5-HT autoreceptors on serotonergic cell bodies and/or dendrites but not terminals are of the 5-HT1A subtypeQ48468938
The putative 5-HT1 receptor agonist, RU 24969, inhibits the efflux of 5-hydroxytryptamine from rat frontal cortex slices by stimulation of the 5-HT autoreceptorQ48485986
5-HT-1a and 5-HT-1b selectivity of two phenylpiperazine derivatives: evidence for 5-HT-1b heterogeneityQ48499755
A functional correlate for the dihydropyridine binding site in rat brainQ48509384
3H-TVX Q 7821: identification of 5-HT1 binding sites as target for a novel putative anxiolyticQ48532640
Low doses of the putative serotonin agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) elicit feeding in the rat.Q48574385
Determination of selective and nonselective compounds for the 5-HT 1A and 5-HT 1B receptor subtypes in rat frontal cortexQ48594638
Brain serotonin receptors as a target for the putative anxiolytic TVX Q 7821.Q48662052
The behavioural effects of RU 24969, a suggested 5-HT1 receptor agonist in rodents and the effect on the behaviour of treatment with antidepressantsQ48663812
Biochemical evidence for the 5-HT agonist properties of PAT (8-hydroxy-2-(di-n-propylamino)tetralin) in the rat brainQ48670125
P433issue2
P921main subjectserotoninQ167934
P304page(s)158-166
P577publication date1987-01-01
P1433published inPsychopharmacologyQ1422802
P1476titleSerotonin receptor subtype mediation of the interoceptive discriminative stimuli induced by 5-methoxy-N,N-dimethyltryptamine
P478volume93

Reverse relations

cites work (P2860)
Q52185700A comparison of N,N-dimethyltryptamine, harmaline, and selected congeners in rats trained with LSD as a discriminative stimulus.
Q30358201Behavioral and pharmacokinetic interactions between monoamine oxidase inhibitors and the hallucinogen 5-methoxy-N,N-dimethyltryptamine.
Q67900241Buspirone affects hippocampal rhythmical slow activity through serotonin1A rather than dopamine D2 receptors
Q37302207Development of a mechanism-based pharmacokinetic/pharmacodynamic model to characterize the thermoregulatory effects of serotonergic drugs in mice
Q24594834Differential contributions of serotonin receptors to the behavioral effects of indoleamine hallucinogens in mice
Q34435958Drug discrimination studies with ibogaine
Q45279141Effect of Hallucinogens on Unconditioned Behavior
Q33887065Effects of monoamine oxidase inhibitor and cytochrome P450 2D6 status on 5-methoxy-N,N-dimethyltryptamine metabolism and pharmacokinetics
Q52176483Further investigations of the serotonergic properties of the ibogaine-induced discriminative stimulus.
Q37315499Hallucinogens as discriminative stimuli in animals: LSD, phenethylamines, and tryptamines
Q36844764Modification of 5-methoxy-N,N-dimethyltryptamine-induced hyperactivity by monoamine oxidase A inhibitor harmaline in mice and the underlying serotonergic mechanisms
Q24620764Multiple receptors contribute to the behavioral effects of indoleamine hallucinogens
Q48963025Pharmacodynamic effects of serotonin (5-HT) receptor ligands in pigs: stimulation of 5-HT2 receptors induces malignant hyperthermia
Q36023615Psilocybin-induced stimulus control in the rat.
Q24633393Psychedelic 5-Methoxy-N,N-Dimethyltryptamine: Metabolism, Pharmacokinetics, Drug Interactions, and Pharmacological Actions
Q34828820S(-)Propranolol as a discriminative stimulus and its comparison to the stimulus effects of cocaine in rats
Q33748918Serotonergic receptor subtypes and hallucinogen-induced stimulus control
Q37914869Serotonin receptors: clinical implications
Q35085860Stimulus control by 5-methoxy-N,N-dimethyltryptamine in wild-type and CYP2D6-humanized mice
Q59341209The Varieties of the Psychedelic Experience: A Preliminary Study of the Association Between the Reported Subjective Effects and the Binding Affinity Profiles of Substituted Phenethylamines and Tryptamines
Q78035734The acute effects of monoamine reuptake inhibitors on the stimulus effects of hallucinogens
Q24645656The behavioral pharmacology of hallucinogens
Q57178557The epidemiology of 5-methoxy- N, N-dimethyltryptamine (5-MeO-DMT) use: Benefits, consequences, patterns of use, subjective effects, and reasons for consumption
Q73363254The paradox of 5-methoxy-N,N-dimethyltryptamine: an indoleamine hallucinogen that induces stimulus control via 5-HT1A receptors
Q34570539The roles of 5-HT1A and 5-HT2 receptors in the effects of 5-MeO-DMT on locomotor activity and prepulse inhibition in rats
Q34312785The stimulus properties of LSD in C57BL/6 mice
Q69202724Trends in drug discrimination research analysed with a cross-indexed bibliography, 1984-1987

Search more.