scholarly article | Q13442814 |
P356 | DOI | 10.3390/IJMS13055866 |
P953 | full work available at URL | https://europepmc.org/articles/PMC3382785 |
https://europepmc.org/articles/PMC3382785?pdf=render | ||
https://www.mdpi.com/1422-0067/13/5/5866/pdf | ||
https://www.mdpi.com/1422-0067/13/5/5866/pdf?version=1403144221 | ||
P932 | PMC publication ID | 3382785 |
P698 | PubMed publication ID | 22754337 |
P5875 | ResearchGate publication ID | 228106114 |
P2093 | author name string | Ying Luo | |
Xiaoming Wu | |||
Xiufeng Zhang | |||
Wenru Tang | |||
P2860 | cites work | Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a) | Q24293520 |
The Werner syndrome protein is a DNA helicase | Q24310486 | ||
A biomarker that identifies senescent human cells in culture and in aging skin in vivo | Q24562644 | ||
Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence | Q24650807 | ||
The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2 | Q28116237 | ||
Shelterin: the protein complex that shapes and safeguards human telomeres | Q28272546 | ||
Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes | Q28509192 | ||
Essential role of limiting telomeres in the pathogenesis of Werner syndrome | Q28588253 | ||
A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity | Q28589633 | ||
p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2 | Q28609749 | ||
Aging or tumor: the crosstalk between telomerase and p53 | Q28611406 | ||
Protection of mammalian telomeres | Q29618391 | ||
p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis | Q33862956 | ||
Mice without telomerase: what can they teach us about human cancer? | Q33995041 | ||
Werner's syndrome a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process | Q34231189 | ||
p16INK4a as a second effector of the telomere damage pathway | Q36264069 | ||
Telomeres: cancer to human aging | Q36528826 | ||
Evaluating the role of p38 MAP kinase in growth of Werner syndrome fibroblasts | Q37764045 | ||
Telomere dysfunction in human keratinocytes elicits senescence and a novel transcription profile | Q38289694 | ||
Different telomere damage signaling pathways in human and mouse cells | Q39647901 | ||
Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence | Q39674577 | ||
Defective telomere lagging strand synthesis in cells lacking WRN helicase activity. | Q40481955 | ||
Accumulation of p16INK4a in mouse fibroblasts as a function of replicative senescence and not of retinoblastoma gene status | Q41098520 | ||
A Review of its Symptomatology, Natural History, Pathologic Features, Genetics And Relationship to the Natural Aging Process | Q55953422 | ||
Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice | Q56508064 | ||
Significant Role for p16INK4a in p53-Independent Telomere-Directed Senescence | Q56969662 | ||
Telomere positional effects and the regulation of cellular senescence | Q68007322 | ||
Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts | Q73311217 | ||
Time, telomeres and tumours: is cellular senescence more than an anticancer mechanism? | Q75294424 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cellular senescence | Q9075999 |
P304 | page(s) | 5866-5877 | |
P577 | publication date | 2012-05-16 | |
P1433 | published in | International Journal of Molecular Sciences | Q3153277 |
P1476 | title | Loss of p16(Ink4a) function rescues cellular senescence induced by telomere dysfunction | |
Loss of p16Ink4a Function Rescues Cellular Senescence Induced by Telomere Dysfunction | |||
P478 | volume | 13 |
Q36502521 | Effects of rhein lysinate on D-galactose-induced aging mice |
Q34757728 | Long-term quiescent fibroblast cells transit into senescence |
Q30442295 | Postnatal development, maturation and aging in the mouse cochlea and their effects on hair cell regeneration |
Q58698149 | Senolytic Cocktail Dasatinib+Quercetin (D+Q) Does Not Enhance the Efficacy of Senescence-Inducing Chemotherapy in Liver Cancer |
Q38873145 | Telomeres and Cell Senescence - Size Matters Not. |
Q34490369 | Up-regulation of leucocytes genes implicated in telomere dysfunction and cellular senescence correlates with depression and anxiety severity scores |
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