Comparison of somatic mutation frequency among immunoglobulin genes

scientific article published on February 1994

Comparison of somatic mutation frequency among immunoglobulin genes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1084/JEM.179.2.395
P932PMC publication ID2191348
P698PubMed publication ID8294856
P5875ResearchGate publication ID277548728

P2093author name stringSuzuki Y
Miwa T
Okada H
Azuma T
Motoyama N
P2860cites workOrganization of the constant-region gene family of the mouse immunoglobulin heavy chainQ34270140
Hypothesis: somatic hypermutation by gene conversion via the error prone DNA----RNA----DNA information loopQ34398630
An immunoglobulin promoter region is unaltered by DNA rearrangement and somatic mutation during B-cell developmentQ35725100
Organization, structure, and assembly of immunoglobulin heavy chain diversity DNA segmentsQ36346092
Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J geneQ36354162
Somatic hypermutation of an immunoglobulin mu heavy chain transgeneQ36361238
Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable regionQ36630020
Physical linkage of mouse lambda genes by pulsed-field gel electrophoresis suggests that the rearrangement process favors proximate target sequencesQ36766471
Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region geneQ37337101
Somatic mutation in constant regions of mouse lambda 1 light chainsQ37591443
Mutation drift and repertoire shift in the maturation of the immune responseQ39658890
Sequences at the somatic recombination sites of immunoglobulin light-chain genesQ39673181
The immunoglobulin kappa locus contains a second, stronger B-cell-specific enhancer which is located downstream of the constant regionQ40818245
Somatic hypermutation of immunoglobulin kappa may depend on sequences 3' of C kappa and occurs on passenger transgenes.Q41081725
Mutation pattern of immunoglobulin transgenes is compatible with a model of somatic hypermutation in which targeting of the mutator is linked to the direction of DNA replicationQ41083928
Murine lambda gene rearrangements: the stochastic model prevails over the ordered modelQ41202410
Somatic point mutations in unrearranged immunoglobulin gene segments encoding the variable region of lambda light chainsQ41337845
A novel enhancer in the immunoglobulin lambda locus is duplicated and functionally independent of NF kappa B.Q41733000
Distribution of mutations around rearranged heavy-chain antibody variable-region genesQ41966971
Clonal recruitment and somatic mutation in the generation of immunological memory to the hapten NPQ42573237
Low frequencies of somatic mutation in two expressed V kappa genes: unequal distribution of mutation in 5' and 3' flanking regionsQ42621194
The mouse IgH 3'-enhancerQ48223460
Somatic mutations of immunoglobulin variable genes are restricted to the rearranged V geneQ48398045
Somatic mutation of immunoglobulin light-chain variable-region genesQ48409137
Differences between germ-line and rearranged immunoglobulin Vκ coding sequences suggest a localized mutation mechanismQ48409267
Origin of Antibody VariationQ59057486
Maturation of the immune response to (4-hydroxy-3-nitrophenyl)-acetyl (NP) haptens in C57BL/6 miceQ69157327
V gene rearrangement is required to fully activate the hypermutation mechanism in B cellsQ69174827
Structure of primary anti-(4-hydroxy-3-nitrophenyl)acetyl (NP) antibodies in normal and idiotypically suppressed C57BL/6 miceQ69868150
Mutations of the chloramphenicol acetyl transferase transgene driven by the immunoglobulin promoter and intron enhancerQ70608716
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)395-403
P577publication date1994-02-01
P1433published inJournal of Experimental MedicineQ3186912
P1476titleComparison of somatic mutation frequency among immunoglobulin genes
P478volume179