Glutamine deprivation alters intestinal tight junctions via a PI3-K/Akt mediated pathway in Caco-2 cells

scientific article published on 11 February 2009

Glutamine deprivation alters intestinal tight junctions via a PI3-K/Akt mediated pathway in Caco-2 cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3945/JN.108.101485
P932PMC publication ID2666365
P698PubMed publication ID19211824
P5875ResearchGate publication ID24002913

P2093author name stringNan Li
Josef Neu
P2860cites workProtein interactions at the tight junction. Actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3Q28138745
Occludin and claudins in tight-junction strands: leading or supporting players?Q33659718
Clostridium difficile toxins disrupt epithelial barrier function by altering membrane microdomain localization of tight junction proteinsQ34006206
Signalling to and from tight junctionsQ34180670
Intestinal barrier: An interface between health and diseaseQ34191359
Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammationQ35065323
Intestinal pathophysiology in autism.Q35139591
Early effects of gliadin on enterocyte intracellular signalling involved in intestinal barrier function.Q35598393
Molecular mechanisms contributing to glutamine-mediated intestinal cell survivalQ36728699
The significance of bowel permeabilityQ36908282
Wasting and intestinal barrier function in children taking alanyl-glutamine-supplemented enteral formulaQ39788100
Tight junctions and the molecular basis for regulation of paracellular permeabilityQ40373935
Effect of stress on the paracellular barrier in the rat ileumQ42015005
Glutamine and barrier function in cultured Caco-2 epithelial cell monolayersQ42444147
PI3K signaling is required for prostaglandin-induced mucosal recovery in ischemia-injured porcine ileum.Q44185456
Glutamine supports recovery from loss of transepithelial resistance and increase of permeability induced by media change in Caco-2 cellsQ44547150
Role of Phosphatidylinositol 3-Kinase in Oxidative Stress-induced Disruption of Tight JunctionsQ44590849
Glutamine regulates Caco-2 cell tight junction proteinsQ44886419
Acetaldehyde disrupts tight junctions and adherens junctions in human colonic mucosa: protection by EGF and L-glutamineQ45271680
The effect of glutamine-enriched enteral nutrition on intestinal permeability in very-low-birth-weight infants: a randomized controlled trial.Q47324044
[Glutamine dipeptide attenuate mucosal atrophic changes and preservation of gut barrier function following 5-FU intervention].Q54436385
Effect of enteral glutamine on intestinal permeability and bacterial translocation after abdominal radiation injury in rats.Q54568741
Effects of Parenteral and Enteral Nutrition on Gut-Associated Lymphoid TissueQ71963349
Luminal Glutamine Perfusion Alters Endotoxin‐Related Changes in Ileal Permeability of the PigletQ72019523
Glutamine synthetase: a key enzyme for intestinal epithelial differentiation?Q77781420
Neonatal maternal separation predisposes adult rats to colonic barrier dysfunction in response to mild stressQ78396324
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectCaco-2Q5016050
P304page(s)710-714
P577publication date2009-02-11
P1433published inJournal of NutritionQ3186931
P1476titleGlutamine deprivation alters intestinal tight junctions via a PI3-K/Akt mediated pathway in Caco-2 cells
P478volume139

Reverse relations

cites work (P2860)
Q37081643Age-associated remodeling of the intestinal epithelial barrier
Q53013784Amino acid deprivation disrupts barrier function and induces protective autophagy in intestinal porcine epithelial cells.
Q90307786Beyond Heat Stress: Intestinal Integrity Disruption and Mechanism-Based Intervention Strategies
Q51376639Characterization of in vitro effects of microcystin-LR on intestinal epithelial cells.
Q27000548Claudins in intestines: Distribution and functional significance in health and diseases
Q35053608Commensal bacteria-dependent indole production enhances epithelial barrier function in the colon
Q54630109Effects of essential amino acids or glutamine deprivation on intestinal permeability and protein synthesis in HCT-8 cells: involvement of GCN2 and mTOR pathways
Q54964046Enterotoxigenic Escherichia coli infection induces tight junction proteins expression in mice.
Q46781710Factors derived from Escherichia coli Nissle 1917, grown in different growth media, enhance cell death in a model of 5-fluorouracil-induced Caco-2 intestinal epithelial cell damage.
Q38223273Glutamine and intestinal barrier function
Q34228766Glutamine and whey protein improve intestinal permeability and morphology in patients with Crohn's disease: a randomized controlled trial
Q41665259Glutamine enhances tight junction protein expression and modulates corticotropin-releasing factor signaling in the jejunum of weanling piglets
Q88337692High-intensity-exercise-induced intestinal damage is protected by fermented milk supplemented with whey protein, probiotic and pomegranate (Punica granatum L.).
Q33715804Homeostasis of the gut barrier and potential biomarkers
Q38715954Insulin signaling via the PI3-kinase/Akt pathway regulates airway glucose uptake and barrier function in a CFTR-dependent manner
Q34450832L-Glutamate supplementation improves small intestinal architecture and enhances the expressions of jejunal mucosa amino acid receptors and transporters in weaning piglets
Q53178021L-Glutamine Enhances Tight Junction Integrity by Activating CaMK Kinase 2-AMP-Activated Protein Kinase Signaling in Intestinal Porcine Epithelial Cells.
Q40292219L-Glutamine and L-arginine protect against enterotoxigenic Escherichia coli infection via intestinal innate immunity in mice
Q54339897L-Glutamine deprivation induces autophagy and alters the mTOR and MAPK signaling pathways in porcine intestinal epithelial cells.
Q38685179MPA Modulates Tight Junctions' Permeability via Midkine/PI3K Pathway in Caco-2 Cells: A Possible Mechanism of Leak-Flux Diarrhea in Organ Transplanted Patients
Q33633997Molecular modulation of intestinal epithelial barrier: contribution of microbiota
Q38081555Novel nutritional substrates in surgery.
Q26772345Nutritional Keys for Intestinal Barrier Modulation
Q43716527Oral glutamine supplementation improves intestinal permeability dysfunction in a murine acute graft-vs.-host disease model
Q36941775Polyphenol-Rich Propolis Extracts Strengthen Intestinal Barrier Function by Activating AMPK and ERK Signaling
Q28287402Possible links between intestinal permeability and food processing: A potential therapeutic niche for glutamine
Q54338019Probiotic factors partially prevent changes to caspases 3 and 7 activation and transepithelial electrical resistance in a model of 5-fluorouracil-induced epithelial cell damage.
Q89659555Processed Food Additive Microbial Transglutaminase and Its Cross-Linked Gliadin Complexes Are Potential Public Health Concerns in Celiac Disease
Q91942029Protective Effects Oncorneal Endothelium During Intracameral Irrigation Using N-(2)-l-alanyl-l-Glutamine
Q53672135Protective and reparative effects of peptides from soybean β-conglycinin on mice intestinal mucosa injury.
Q55087094Regulation of Intestinal Epithelial Cells Properties and Functions by Amino Acids.
Q34287155Regulation of intestinal epithelial permeability by tight junctions.
Q90705632Regulation of the intestinal barrier by nutrients: The role of tight junctions
Q92587390Review: The roles and functions of glutamine on intestinal health and performance of weaning pigs
Q34468725Role of Glutamine in Protection of Intestinal Epithelial Tight Junctions
Q38696638Signaling pathways induced by serine proteases to increase intestinal epithelial barrier function.
Q61448106The Role of Dietary Nutrients in Inflammatory Bowel Disease
Q39302506The Roles of Glutamine in the Intestine and Its Implication in Intestinal Diseases

Search more.