The Roles of Glutamine in the Intestine and Its Implication in Intestinal Diseases

scientific article

The Roles of Glutamine in the Intestine and Its Implication in Intestinal Diseases is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3390/IJMS18051051
P932PMC publication ID5454963
P698PubMed publication ID28498331

P2093author name stringHyeyoung Kim
Min-Hyun Kim
P2860cites workXBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel diseaseQ22252318
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Lessons from genetically engineered animal models. VII. Apoptosis in intestinal epithelium: lessons from transgenic and knockout miceQ33822567
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Metabolic response of muscle to alanine, glutamine, and valine supplementation during severe illnessQ44583156
Glutamine and transforming growth factor-alpha stimulate extracellular regulated kinases and enhance recovery of villous surface area in porcine ischemic-injured intestineQ44870903
Glutamine regulates Caco-2 cell tight junction proteinsQ44886419
L-Glutamine ameliorates acetaldehyde-induced increase in paracellular permeability in Caco-2 cell monolayerQ45032126
Amino acids suppress apoptosis induced by sodium laurate, an absorption enhancer.Q45920868
NF-κB is 25.Q46097461
Glutamine modulates CD8αα(+) TCRαβ(+) intestinal intraepithelial lymphocyte expression in mice with polymicrobial sepsisQ46101914
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Glutamine attenuates lung injury and improves survival after sepsis: role of enhanced heat shock protein expressionQ46533733
Randomised trial of glutamine, selenium, or both, to supplement parenteral nutrition for critically ill patientsQ47590936
L-Glutamine Enhances Tight Junction Integrity by Activating CaMK Kinase 2-AMP-Activated Protein Kinase Signaling in Intestinal Porcine Epithelial Cells.Q53178021
Glutamine modulates acute dextran sulphate sodium-induced changes in small-intestinal intraepithelial γδ-T-lymphocyte expression in mice.Q54235824
Modulation of glutamine metabolism by the PI(3)K-PKB-FOXO network regulates autophagy.Q54495638
Glutamine deprivation induces apoptosis in intestinal epithelial cells.Q57773641
Autophagy in the intestinal epithelium reduces endotoxin-induced inflammatory responses by inhibiting NF-κB activationQ63609779
Absorption and metabolic effects of enterally administered glutamine in humansQ67988725
L-glutamine inhibits the release of endothelium-derived relaxing factor from the rabbit aortaQ68575443
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Muscle and plasma amino acids following injury. Influence of intercurrent infectionQ71288582
Parenteral nutrition is associated with intestinal morphologic and functional changes in humansQ71369086
Response of glutamine metabolism to exogenous glutamine in humansQ71552988
Gut adaptation and the insulin-like growth factor system: regulation by glutamine and IGF-I administrationQ71836477
Apoptosis of crypt epithelial cells in ulcerative colitisQ71928770
Effect of growth hormone, glutamine, and diet on body composition in short bowel syndrome: a randomized, controlled studyQ73211011
L-glutamine stimulates intestinal cell proliferation and activates mitogen-activated protein kinasesQ73399527
Six-month outcome of critically ill patients given glutamine-supplemented parenteral nutritionQ73403151
Effects of an isotonic oral rehydration solution, enriched with glutamine, on fluid and sodium absorption in patients with a short-bowelQ73716968
Effect of growth hormone, glutamine, and diet on adaptation in short-bowel syndrome: a randomized, controlled studyQ73760524
Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylationQ73847660
Enteral versus parenteral nutritionQ74260915
A double-blind placebo-controlled pilot study of glutamine therapy for abnormal intestinal permeability in patients with AIDSQ74730531
Dietary glutamine supplementation reduces plasma nitrate levels in ratsQ77330866
Heat shock inhibits activation of NF-kappaB in the absence of heat shock factor-1Q77663433
Effect of long-term oral glutamine supplements on small intestinal permeability in patients with Crohn's diseaseQ77794423
Low intestinal glutamine level and low glutaminase activity in Crohn's disease: a rational for glutamine supplementation?Q79320465
Glutamine and the immune systemQ79913486
Glutamine metabolism by lymphocytes, macrophages, and neutrophils: its importance in health and diseaseQ80991633
Protein kinase C enhances tight junction barrier function of human nasal epithelial cells in primary culture by transcriptional regulationQ81269869
Route of administration (enteral or parenteral) affects the contribution of L-glutamine to de novo L-arginine synthesis in mice: a stable-isotope studyQ83309995
Glutamine therapy improves outcome of in vitro and in vivo experimental colitis modelsQ83540697
Glutamine modulates sepsis-induced changes to intestinal intraepithelial γδT lymphocyte expression in miceQ84551569
Effects of alanyl-glutamine dipeptide on the expression of colon-inflammatory mediators during the recovery phase of colitis induced by dextran sulfate sodiumQ84676732
The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: cultured endothelial cells recycle L-citrulline to L-arginineQ33882001
Double-blind randomized controlled trial of glutamine-enriched polymeric diet in the treatment of active Crohn's diseaseQ33886201
Why is L-glutamine metabolism important to cells of the immune system in health, postinjury, surgery or infection?Q33954365
Regulative potential of glutamine--relation to glutathione metabolism.Q33957782
Nitric oxide and intestinal inflammationQ34019768
The Stat family in cytokine signalingQ34180677
Glutamine and whey protein improve intestinal permeability and morphology in patients with Crohn's disease: a randomized controlled trialQ34228766
Heat shock proteins: endogenous modulators of apoptotic cell deathQ34340472
Nitric oxide in immunity and inflammationQ34342605
Glutamine metabolism in sepsis and infectionQ34353985
Intestinal inflammation and mucosal barrier functionQ34438743
Glutamine treatment attenuates endoplasmic reticulum stress and apoptosis in TNBS-induced colitisQ34500273
Glutamine and heat shock protein expressionQ34554295
Glutamine and its relationship with intracellular redox status, oxidative stress and cell proliferation/deathQ34572853
MAPK signal pathways in the regulation of cell proliferation in mammalian cellsQ34593370
Glutamine supplementation in serious illness: a systematic review of the evidenceQ34916175
Intestinal epithelial cell apoptosis and loss of barrier function in the setting of altered microbiota with enteral nutrient deprivation.Q35083579
Clinical evidence for enteral nutritional support with glutamine: a systematic reviewQ35201118
Intestinal fuels: glutamine, short-chain fatty acids, and dietary fiberQ35234085
Effect of high dose growth hormone with glutamine and no change in diet on intestinal absorption in short bowel patients: a randomised, double blind, crossover, placebo controlled studyQ35360775
Glutamine: metabolism and application in nutrition support.Q35683679
Regulation of tight junctions and loss of barrier function in pathophysiologyQ35756449
Prophylactic effect of dietary glutamine supplementation on interleukin 8 and tumour necrosis factor alpha production in trinitrobenzene sulphonic acid induced colitisQ35841124
Gastrointestinal stem cells. II. Intestinal stem cellsQ36225076
Caspase family proteases and apoptosisQ36306299
Molecular mechanisms contributing to glutamine-mediated intestinal cell survivalQ36728699
Glutamine: mode of action in critical illnessQ36916515
Exogenous glutamine: the clinical evidenceQ36916518
Crosstalk of tight junction components with signaling pathwaysQ36976365
Myosin light chain kinase signaling in endothelial barrier dysfunctionQ37076073
Glutamine increases autophagy under Basal and stressed conditions in intestinal epithelial cellsQ37171062
Glutamine, arginine, and leucine signaling in the intestineQ37364534
Apoptosis of human intestinal epithelial cells after bacterial invasionQ37387961
Effects of dietary glutamine on the homeostasis of CD4+ T cells in mice with dextran sulfate sodium-induced acute colitisQ37458560
Vascular endothelial tight junctions and barrier function are disrupted by 15(S)-hydroxyeicosatetraenoic acid partly via protein kinase C ε-mediated zona occludens-1 phosphorylation at threonine 770/772.Q37563388
Is glutamine a conditionally essential amino acid?Q37783687
Intestinal inflammation and cancerQ37870432
A review of the role of acid-base balance in amino acid nutritionQ37906136
Roles of glutamine in neurotransmission.Q37948212
Autophagy and intestinal homeostasisQ38065286
Metabolic regulation of immune responsesQ38198155
Glutamine and intestinal barrier functionQ38223273
Oncogenes and tumor suppressors regulate glutamine metabolism in cancer cellsQ38261953
Mechanism of glutamine-mediated amelioration of lipopolysaccharide-induced IL-8 production in Caco-2 cellsQ38343072
Is insulin-like growth factor 1 (IGF-1) system an attractive target inflammatory bowel diseases? Benefits and limitation of potential therapyQ38818356
Tight junctions: from simple barriers to multifunctional molecular gatesQ38879992
Celiac Disease: Role of the Epithelial BarrierQ38919389
Cytokines in inflammatory bowel diseaseQ39206254
L-Glutamine or L-alanyl-L-glutamine prevents oxidant- or endotoxin-induced death of neonatal enterocytesQ39888150
Tight junctions and the molecular basis for regulation of paracellular permeabilityQ40373935
Anti-apoptotic effects of L-glutamine-mediated transcriptional modulation of the heat shock protein 72 during heat shockQ40398361
Glutamine modulates LPS-induced IL-8 production through IkappaB/NF-kappaB in human fetal and adult intestinal epithelium.Q40465533
Cell death by apoptosis: basic concepts and disease relevance for the gastroenterologistQ40945812
Possible involvement of phosphorylation of occludin in tight junction formationQ41104367
Oral glutamine reduces bacterial translocation following abdominal radiationQ41222683
STAT signaling in inflammationQ41392782
CK2-dependent phosphorylation of occludin regulates the interaction with ZO-proteins and tight junction integrity.Q41506361
Glutamine is essential for epidermal growth factor-stimulated intestinal cell proliferation.Q41540354
Glutamine and nucleotide metabolism within enterocytesQ41732344
Molecular architecture of tight junctionsQ41748256
A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn diseaseQ41904813
MAPK interacts with occludin and mediates EGF-induced prevention of tight junction disruption by hydrogen peroxideQ41964987
Glutamine deprivation alters intestinal tight junctions via a PI3-K/Akt mediated pathway in Caco-2 cellsQ42251542
A randomized trial of glutamine and antioxidants in critically ill patientsQ42266312
Glutamine and barrier function in cultured Caco-2 epithelial cell monolayersQ42444147
Glutamine pretreatment reduces IL-8 production in human intestinal epithelial cells by limiting IkappaBalpha ubiquitinationQ42495415
Parenteral L-alanyl-L-glutamine improves 6-month outcome in critically ill patientsQ42684404
Quantitative aspects of glucose and glutamine metabolism by intestinal cellsQ43218755
Plasma glutamine depletion and patient outcome in acute ICU admissionsQ43561049
Effect of glutamine in short-bowel syndromeQ43691523
Infection, multiple organ failure, and survival in the intensive care unit: influence of glutamine-supplemented parenteral nutrition on acquired infectionQ44047192
Glutamine and arginine improve permeability and tight junction protein expression in methotrexate-treated Caco-2 cellsQ44427054
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue5
P407language of work or nameEnglishQ1860
P921main subjecthuman digestive systemQ9649
amino acidQ8066
inflammatory bowel diseasesQ917447
tissueQ40397
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P577publication date2017-05-12
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleThe Roles of Glutamine in the Intestine and Its Implication in Intestinal Diseases
P478volume18

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