A new kind of membrane-tethered eukaryotic transcription factor that shares an auto-proteolytic processing mechanism with bacteriophage tail-spike proteins

scientific article published on 17 September 2013

A new kind of membrane-tethered eukaryotic transcription factor that shares an auto-proteolytic processing mechanism with bacteriophage tail-spike proteins is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1242/JCS.133231
P932PMC publication ID3828593
P698PubMed publication ID24046445

P2093author name stringJeffrey G Williams
Tsuyoshi Araki
Hiroshi Senoo
Masashi Fukuzawa
P2860cites workMYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genesQ21090170
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stressQ22010800
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPsQ24290776
An orthologue of the Myelin-gene Regulatory Transcription Factor regulates Dictyostelium prestalk differentiationQ24612888
Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelinationQ24657511
Crystal structure of an intramolecular chaperone mediating triple-beta-helix foldingQ27659320
Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing.Q27937925
Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humansQ28145545
Improved green fluorescenceQ28307219
A Bacteriophage tailspike domain promotes self-cleavage of a human membrane-bound transcription factor, the myelin regulatory factor MYRFQ28535280
Interaptin, an actin-binding protein of the alpha-actinin superfamily in Dictyostelium discoideum, is developmentally and cAMP-regulated and associates with intracellular membrane compartmentsQ32040709
Notch signal transduction: a real rip and moreQ33964063
Growth of myxamoebae of the cellular slime mould Dictyostelium discoideum in axenic cultureQ41826297
The initiation of basal disc formation in Dictyostelium discoideum is an early event in culmination.Q42517653
Analysis of cell movement during the culmination phase of Dictyostelium development.Q42517658
A bZIP/bRLZ transcription factor required for DIF signaling in DictyosteliumQ44732784
New prestalk and prespore inducing signals in DictyosteliumQ46541117
Two distinct populations of prestalk cells within the tip of the migratory Dictyostelium slug with differing fates at culmination.Q48118364
The role of DIF-1 signaling in Dictyostelium development.Q52141453
Characterization of a novel intramolecular chaperone domain conserved in endosialidases and other bacteriophage tail spike and fiber proteins.Q53583830
Dictyostelium discoideumprotein disulfide isomerase, an endoplasmic reticulum resident enzyme lacking a KDEL-type retrieval signalQ56985675
Fate and regulation of anterior-like cells in Dictyostelium slugsQ70479321
P275copyright licenseCreative Commons Attribution-NonCommercial-ShareAlike 3.0 UnportedQ15643954
P6216copyright statuscopyrightedQ50423863
P433issuePt 22
P407language of work or nameEnglishQ1860
P921main subjectproteolysisQ33123
bacteriophageQ165028
P304page(s)5247-5258
P577publication date2013-09-17
P1433published inJournal of Cell ScienceQ1524177
P1476titleA new kind of membrane-tethered eukaryotic transcription factor that shares an auto-proteolytic processing mechanism with bacteriophage tail-spike proteins
P478volume126

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cites work (P2860)
Q33807969Crystal structure of the DNA-binding domain of Myelin-gene Regulatory Factor
Q91239785Elucidating the transactivation domain of the pleiotropic transcription factor Myrf
Q92824099Functional mechanism and pathogenic potential of MYRF ICA domain mutations implicated in birth defects
Q32874792Myrf ER-Bound Transcription Factors Drive C. elegans Synaptic Plasticity via Cleavage-Dependent Nuclear Translocation
Q35034376Playing the field: Sox10 recruits different partners to drive central and peripheral myelination
Q52609460The nuclear transportation routes of membrane-bound transcription factors.
Q64885738Variants in myelin regulatory factor (MYRF) cause autosomal dominant and syndromic nanophthalmos in humans and retinal degeneration in mice.

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