Elucidating the transactivation domain of the pleiotropic transcription factor Myrf

scientific article published on 30 August 2018

Elucidating the transactivation domain of the pleiotropic transcription factor Myrf is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41598-018-31477-4
P932PMC publication ID6117317
P698PubMed publication ID30166609

P50authorYungki ParkQ91239781
P2093author name stringChuandong Fan
Mohamed Sharif
Dongkyeong Kim
Hongjoo An
Jin-Ok Choi
P2860cites workMYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genesQ21090170
An orthologue of the Myelin-gene Regulatory Transcription Factor regulates Dictyostelium prestalk differentiationQ24612888
Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelinationQ24657511
Mapping the SUMOylated landscapeQ26799547
Analysis of protein-coding genetic variation in 60,706 humansQ26831376
Structural Basis for Dimerization in DNA Recognition by Gal4Q27651074
Crystal structure of an intramolecular chaperone mediating triple-beta-helix foldingQ27659320
Mechanisms, regulation and consequences of protein SUMOylationQ27865251
Concepts in sumoylation: a decade onQ28257220
Myelin gene regulatory factor is required for maintenance of myelin and mature oligodendrocyte identity in the adult CNSQ28274507
A Bacteriophage tailspike domain promotes self-cleavage of a human membrane-bound transcription factor, the myelin regulatory factor MYRFQ28535280
Regulation of the C. elegans molt by pqn-47.Q30538454
Myrf ER-Bound Transcription Factors Drive C. elegans Synaptic Plasticity via Cleavage-Dependent Nuclear TranslocationQ32874792
Homo-trimerization is essential for the transcription factor function of Myrf for oligodendrocyte differentiationQ33701686
Crystal structure of the DNA-binding domain of Myelin-gene Regulatory FactorQ33807969
The dynamics and mechanism of SUMO chain deconjugation by SUMO-specific proteasesQ34695640
Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain.Q36558058
SUMOylation and De-SUMOylation: wrestling with life's processesQ37325310
SUMOylation and deSUMOylation at a glanceQ37425378
Myelin regulatory factor drives remyelination in multiple sclerosisQ38718081
Lines of murine oligodendroglial precursor cells immortalized by an activated neu tyrosine kinase show distinct degrees of interaction with axons in vitro and in vivo.Q41341474
Differential activation of CREB by Ca2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activityQ41430917
CG-4, a new bipotential glial cell line from rat brain, is capable of differentiating in vitro into either mature oligodendrocytes or type-2 astrocytesQ41645595
Transient structure and dynamics in the disordered c-Myc transactivation domain affect Bin1 bindingQ42053910
A new kind of membrane-tethered eukaryotic transcription factor that shares an auto-proteolytic processing mechanism with bacteriophage tail-spike proteinsQ42268648
Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands.Q46564299
Motor skill learning requires active central myelination.Q48482406
MYRF is associated with encephalopathy with reversible myelin vacuolizationQ50424245
De novo variants in Myelin regulatory factor (MYRF) as candidates of a new syndrome of cardiac and urogenital anomalies.Q52694801
Characterization of a novel intramolecular chaperone domain conserved in endosialidases and other bacteriophage tail spike and fiber proteins.Q53583830
P433issue1
P921main subjectpleiotropyQ1134884
P304page(s)13075
P577publication date2018-08-30
P1433published inScientific ReportsQ2261792
P1476titleElucidating the transactivation domain of the pleiotropic transcription factor Myrf
P478volume8

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cites work (P2860)
Q92296537A principled strategy for mapping enhancers to genes
Q92824099Functional mechanism and pathogenic potential of MYRF ICA domain mutations implicated in birth defects
Q90058181Molecular mechanism for the multiple sclerosis risk variant rs17594362
Q64885738Variants in myelin regulatory factor (MYRF) cause autosomal dominant and syndromic nanophthalmos in humans and retinal degeneration in mice.

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