The interaction of canonical bone morphogenetic protein- and Wnt-signaling pathways may play an important role in regulating cartilage degradation in osteoarthritis.

scientific article published on 6 June 2012

The interaction of canonical bone morphogenetic protein- and Wnt-signaling pathways may play an important role in regulating cartilage degradation in osteoarthritis. is …
instance of (P31):
editorialQ871232
scholarly articleQ13442814

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P6179Dimensions Publication ID1019410978
P356DOI10.1186/AR3837
P932PMC publication ID3446488
P698PubMed publication ID22676306
P5875ResearchGate publication ID225281561

P50authorChristopher B LittleQ58048957
P2093author name stringBenjamin Y Chan
P2860cites workBone morphogenetic protein-2-induced Wnt/β-catenin signaling pathway activation through enhanced low-density-lipoprotein receptor-related protein 5 catabolic activity contributes to hypertrophy in osteoarthritic chondrocytesQ36245833
Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer.Q37453892
Crosstalk between Wnt and bone morphogenic protein signaling: a turbulent relationshipQ37526818
Chondrocyte hypertrophy and osteoarthritis: role in initiation and progression of cartilage degeneration?Q37969480
Roles of β-catenin signaling in phenotypic expression and proliferation of articular cartilage superficial zone cellsQ42148680
Involvement of the Wnt signaling pathway in experimental and human osteoarthritis: prominent role of Wnt-induced signaling protein 1.Q45748576
Dickkopf-1 is a master regulator of joint remodelingQ79610564
Articular cartilage and biomechanical properties of the long bones in Frzb-knockout miceQ80123636
Wnt signaling as a therapeutic target for bone diseasesQ83588890
Increased chondrocyte sclerostin may protect against cartilage degradation in osteoarthritisQ84211298
Opposite relationships between circulating Dkk-1 and cartilage breakdown in patients with rheumatoid arthritis and knee osteoarthritisQ84393851
Distinct modes of inhibition by sclerostin on bone morphogenetic protein and Wnt signaling pathwaysQ24621990
BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development.Q35388963
P433issue3
P921main subjectmorphogenesisQ815547
osteoarthritisQ62736
cartilageQ502730
P304page(s)119
P577publication date2012-06-06
P1433published inArthritis Research and TherapyQ15757229
P1476titleThe interaction of canonical bone morphogenetic protein- and Wnt-signaling pathways may play an important role in regulating cartilage degradation in osteoarthritis
P478volume14

Reverse relations

cites work (P2860)
Q35360046CD4 T-cell transcriptome analysis reveals aberrant regulation of STAT3 and Wnt signaling pathways in rheumatoid arthritis: evidence from a case-control study
Q57340466Nanoparticles for Stem-Cell Engineering
Q37027619Role of Chondrocytes in Cartilage Formation, Progression of Osteoarthritis and Cartilage Regeneration
Q26796645The Regulatory Role of Signaling Crosstalk in Hypertrophy of MSCs and Human Articular Chondrocytes

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