Disruption of the Smad7 gene enhances CCI4-dependent liver damage and fibrogenesis in mice

scientific article published on 4 February 2008

Disruption of the Smad7 gene enhances CCI4-dependent liver damage and fibrogenesis in mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1582-4934.2008.00262.X
P932PMC publication ID4506177
P698PubMed publication ID18266971
P5875ResearchGate publication ID5585137

P50authorLoredana CiuclanQ114737335
Jafar HamzaviQ114737430
Rainer HeuchelQ42353151
P2093author name stringSteven Dooley
Patricio Godoy
Honglei Weng
Peter R Mertens
Sabrina Ehnert
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Smad7: a new key player in TGF-beta-associated diseaseQ74486070
Inhibition of Smad7 with a specific antisense oligonucleotide facilitates TGF-beta1-mediated suppression of colitisQ79333602
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Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3Q24550794
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IFN-gamma abrogates profibrogenic TGF-beta signaling in liver by targeting expression of inhibitory and receptor SmadsQ40204600
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Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiationQ42160419
Role of cytochrome P-450 2E1 in ethanol-, carbon tetrachloride- and iron-dependent microsomal lipid peroxidationQ42455526
Conditional tetracycline-regulated expression of TGF-β1 in liver of transgenic mice leads to reversible intermediary fibrosisQ44419371
Smad7 prevents activation of hepatic stellate cells and liver fibrosis in ratsQ44507331
Involvement of mitochondria in acetaminophen-induced apoptosis and hepatic injury: roles of cytochrome c, Bax, Bid, and caspasesQ44567499
Long-term treatment with insulin induces apoptosis in brown adipocytes: role of oxidative stress.Q44590737
Source of early reactive oxygen species in the apoptosis induced by transforming growth factor-beta in fetal rat hepatocytesQ44734271
Genomic locus and promoter region of rat Smad7, an important antagonist of TGFbeta signalingQ47887730
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Multiple roles of mouse Numb in tuning developmental cell fates.Q52133869
P433issue5B
P304page(s)2130-2144
P577publication date2008-02-04
P1433published inJournal of Cellular and Molecular MedicineQ1524063
P1476titleDisruption of the Smad7 gene enhances CCI4-dependent liver damage and fibrogenesis in mice
P478volume12