Conditional tetracycline-regulated expression of TGF-β1 in liver of transgenic mice leads to reversible intermediary fibrosis

scientific article published on May 1, 2003

Conditional tetracycline-regulated expression of TGF-β1 in liver of transgenic mice leads to reversible intermediary fibrosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1053/JHEP.2003.50196
P953full work available at URLhttps://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1053%2Fjhep.2003.50196
https://onlinelibrary.wiley.com/doi/full/10.1053/jhep.2003.50196
P698PubMed publication ID12717387
P5875ResearchGate publication ID10785982

P50authorRolf GebhardtQ99628521
P2093author name stringHermann Bujard
Kai Schönig
Elke Ueberham
Uwe Ueberham
Rainer Löw
P2860cites workThe New England Journal of MedicineQ582728
American Journal of PhysiologyQ2160146
Journal of ImmunologyQ3521441
Journal of PhysiologyQ7743612
Tight control of gene expression in mammalian cells by tetracycline-responsive promotersQ24564850
Cytokines and fibrogenesisQ33697040
Is liver fibrosis reversible?Q33862568
Autocrine induction of tumor protease production and invasion by a metallothionein-regulated TGF-beta 1 (Ser223, 225)Q33937674
Extracellular matrix degradation and the role of hepatic stellate cellsQ34391375
Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesionsQ34480115
Oxidative stress, plant-derived antioxidants and liver fibrosisQ34623869
Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitroQ35610349
Altered balance between matrix metalloproteinases and their inhibitors in experimental biliary fibrosisQ35785934
In vivo inhibition of rat stellate cell activation by soluble transforming growth factor beta type II receptor: a potential new therapy for hepatic fibrosisQ36553502
Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1Q37058555
Blockade of type beta transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat.Q37182998
Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic miceQ37303897
Hepatic fibrosis, glomerulosclerosis, and a lipodystrophy-like syndrome in PEPCK-TGF-beta1 transgenic miceQ37375446
Experimental models of hepatic fibrosis: a reviewQ37812210
Cellular sources of noncollagenous matrix proteins: role of fat-storing cells in fibrogenesisQ37921927
Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitorsQ39807542
Endotoxin, reticuloendothelial function, and liver injuryQ40320109
Co-regulation of two gene activities by tetracycline via a bidirectional promoter.Q40395769
Transforming growth factor-beta 1 in reproduction and developmentQ40573466
Tet repressor-based system for regulated gene expression in eukaryotic cells: principles and advancesQ40846822
Mechanism of endotoxin desensitization: involvement of interleukin 10 and transforming growth factor betaQ42124595
Liver injury related to amoxycillin-clavulanic acid: interlobular bile-duct lesions and extrahepatic manifestationsQ42279177
Dose-dependent inhibition of hepatic fibrosis in mice by a TGF-beta soluble receptor: implications for antifibrotic therapyQ43974807
In situ hybridization for procollagen types I, III and IV mRNA in normal and fibrotic rat liver: evidence for predominant expression in nonparenchymal liver cells.Q53038196
Inhibitory effect of transforming growth factor-beta on DNA synthesis of adult rat hepatocytes in primary cultureQ69924795
A simple method to determine nanogram levels of 4-hydroxyproline in biological tissuesQ70859629
Lipopolysaccharide-neutralizing antibody reduces hepatocyte injury from acute hepatotoxin administrationQ72402221
Tissue inhibitor of metalloproteinases-1 promotes liver fibrosis development in a transgenic mouse modelQ73229679
Matrix degradation in liver: a role in injury and repairQ73782049
Expression of matrix metalloproteinases and their inhibitors during hepatic tissue repair in the ratQ74136816
Endless healing: TGF-beta, SMADs, and fibrosisQ74601263
Expression patterns of matrix metalloproteinases and their inhibitors in parenchymal and non-parenchymal cells of rat liver: regulation by TNF-alpha and TGF-beta1Q77932181
P433issue5
P407language of work or nameEnglishQ1860
P921main subjecttetracyclineQ193045
animal disease modelQ64732998
transgenic miceQ69382071
P304page(s)1067-1078
P577publication date2003-05-01
P1433published inHepatologyQ15724398
P1476titleConditional tetracycline-regulated expression of TGF-beta1 in liver of transgenic mice leads to reversible intermediary fibrosis
Conditional tetracycline-regulated expression of TGF-β1 in liver of transgenic mice leads to reversible intermediary fibrosis
P478volume37

Reverse relations

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