A New Trick for a Conserved Enzyme: Mevalonate Kinase, a Glycosomal Enzyme, Can Be Secreted by Trypanosoma cruzi and Modulate Cell Invasion and Signaling. Is It Another Moonlighting Enzyme?

scientific article published on 29 September 2017

A New Trick for a Conserved Enzyme: Mevalonate Kinase, a Glycosomal Enzyme, Can Be Secreted by Trypanosoma cruzi and Modulate Cell Invasion and Signaling. Is It Another Moonlighting Enzyme? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FCIMB.2017.00426
P953full work available at URLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627032
P932PMC publication ID5627032
P698PubMed publication ID29034216

P2093author name stringDiana Bahia
P2860cites workAldolase provides an unusual binding site for thrombospondin-related anonymous protein in the invasion machinery of the malaria parasiteQ24681109
Interactions between Trypanosoma cruzi Secreted Proteins and Host Cell Signaling PathwaysQ26749609
A conserved molecular motor drives cell invasion and gliding motility across malaria life cycle stages and other apicomplexan parasitesQ27230081
Systems Biology Approach to Model the Life Cycle of Trypanosoma cruziQ27330520
Plasmodium falciparum enolase: stage-specific expression and sub-cellular localizationQ27973861
Regulation of luteinizing hormone receptor mRNA expression by mevalonate kinase--role of the catalytic center in mRNA recognitionQ28280829
Physical Features of Intracellular Proteins that Moonlight on the Cell SurfaceQ28545748
Enolase as a plasminogen binding protein in Leishmania mexicanaQ28910468
Trypanosoma cruzi extracellular amastigotes and host cell signaling: more pieces to the puzzleQ33354930
Glyceraldehyde-3-phosphate dehydrogenase is a surface-associated, fibronectin-binding protein of Trichomonas vaginalisQ33432490
Moonlighting proteins.Q33543960
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Moonlighting proteins: an intriguing mode of multitaskingQ34097860
Unique behavior of Trypanosoma cruzi mevalonate kinase: A conserved glycosomal enzyme involved in host cell invasion and signalingQ36835636
Moonlighting enzymes in parasitic protozoaQ37710181
Molecular chaperones and protein-folding catalysts as intercellular signaling regulators in immunity and inflammation.Q37743010
Bacterial moonlighting proteins and bacterial virulenceQ37965015
Extracellular functions of glycolytic enzymes of parasites: unpredicted use of ancient proteinsQ38193946
Moonlighting proteins as virulence factors of pathogenic fungi, parasitic protozoa and multicellular parasitesQ38240717
Metabolic dysregulation in monogenic disorders and cancer - finding method in madnessQ38530400
Divergent regulation of dihydrofolate reductase between malaria parasite and human hostQ40736921
Endocrine peptides 'moonlighting' as immune modulators: roles for somatostatin and GH-releasing factorQ40936364
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Commentary: Systems Biology Approach to Model the Life Cycle of Trypanosoma cruziQ42408806
Aldolase Forms a Bridge between Cell Surface Adhesins and the Actin Cytoskeleton in Apicomplexan ParasitesQ44420141
Hemoglobin receptor in Leishmania is a hexokinase located in the flagellar pocketQ45173341
Intracellular location of the early steps of the isoprenoid biosynthetic pathway in the trypanosomatids Leishmania major and Trypanosoma brucei.Q46320655
Telomeres: moonlighting by DNA repair proteinsQ47849834
Leishmania mexicana: molecular cloning and characterization of enolaseQ48080625
The role of luteinizing hormone/human chorionic gonadotropin receptor-specific mRNA binding protein in regulating receptor expression in human ovarian granulosa cellsQ82902378
P407language of work or nameEnglishQ1860
P921main subjectTrypanosoma cruziQ150162
P304page(s)426
P577publication date2017-09-29
P1433published inFrontiers in Cellular and Infection MicrobiologyQ27724376
P1476titleA New Trick for a Conserved Enzyme: Mevalonate Kinase, a Glycosomal Enzyme, Can Be Secreted by Trypanosoma cruzi and Modulate Cell Invasion and Signaling. Is It Another Moonlighting Enzyme?
P478volume7

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Q99711499Comparative Analysis of the Secretome and Interactome of Trypanosoma cruzi and Trypanosoma rangeli Reveals Species Specific Immune Response Modulating Proteinscites workP2860

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