scholarly article | Q13442814 |
P50 | author | Jochen Brumm | Q57274942 |
Joseph R Arron | Q61147913 | ||
P2093 | author name string | Fang Cai | |
Cécile T J Holweg | |||
Emma Doran | |||
Kit Wong | |||
P2860 | cites work | Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity | Q24630261 |
Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses | Q28115227 | ||
IL-13 effector functions | Q28180348 | ||
Prevalence of nasal polyps in adults: the Skövde population-based study | Q28198686 | ||
Mechanism of Siglec-8-mediated cell death in IL-5-activated eosinophils: role for reactive oxygen species-enhanced MEK/ERK activation | Q28290873 | ||
Interleukin-13: central mediator of allergic asthma | Q28291712 | ||
Serum eosinophil granule proteins predict asthma risk in allergic rhinitis | Q28306331 | ||
Common variants at 5q22 associate with pediatric eosinophilic esophagitis | Q28943383 | ||
Eosinophilic Inflammation in Asthma | Q29031455 | ||
Asthma outcomes: biomarkers | Q30425168 | ||
Eosinophil extracellular DNA trap cell death mediates lytic release of free secretion-competent eosinophil granules in humans. | Q30537562 | ||
Lebrikizumab in moderate-to-severe asthma: pooled data from two randomised placebo-controlled studies | Q30957004 | ||
A clinical and pathological study of fatal cases of status asthmaticus | Q33602723 | ||
Epidemiology of eosinophilic esophagitis | Q33606276 | ||
IL-4 regulates skin homeostasis and the predisposition toward allergic skin inflammation | Q33723349 | ||
Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease | Q34003041 | ||
Analysis and expansion of the eosinophilic esophagitis transcriptome by RNA sequencing | Q34143183 | ||
Interleukin-4 and interleukin-13 compromise the sinonasal epithelial barrier and perturb intercellular junction protein expression | Q34154139 | ||
Endotypes and phenotypes of chronic rhinosinusitis: a PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology | Q34165569 | ||
Lebrikizumab treatment in adults with asthma | Q34205683 | ||
TNF-α/IL-17 synergy inhibits IL-13 bioactivity via IL-13Rα2 induction | Q34294635 | ||
The International Study of Asthma and Allergies in Childhood (ISAAC) Phase Three: a global synthesis | Q34329799 | ||
Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis | Q34331377 | ||
Eosinophil cytokines, chemokines, and growth factors: emerging roles in immunity | Q34479428 | ||
IL-13Rα2 Has a Protective Role in a Mouse Model of Cutaneous Inflammation | Q34610797 | ||
European Position Paper on Rhinosinusitis and Nasal Polyps 2012. | Q34640008 | ||
The expanding role(s) of eosinophils in health and disease | Q34641880 | ||
European position paper on rhinosinusitis and nasal polyps 2007. | Q34685273 | ||
A central regulatory role for eosinophils and the eotaxin/CCR3 axis in chronic experimental allergic airway inflammation | Q35133853 | ||
Biologic therapies targeting eosinophils: current status and future prospects | Q35565533 | ||
Keratinocytes in atopic dermatitis: inflammatory signals | Q35790937 | ||
Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway. | Q51699174 | ||
Full blood count parameters for the detection of asthma inflammatory phenotypes. | Q51722268 | ||
Prevalence of nasal polyposis in France: a cross-sectional, case-control study. | Q51980474 | ||
Bioanalytical challenges and improved detection of circulating levels of IL-13. | Q53186302 | ||
IL-13 gene expression in patients with atopic dermatitis: relation to IgE level and to disease severity. | Q53620595 | ||
Total Eosinophil Counts in the Management of Bronchial Asthma | Q54626180 | ||
The Relation Between Peripheral Blood Leukocyte Counts and Respiratory Symptoms, Atopy, Lung Function, and Airway Responsiveness in Adults | Q57415805 | ||
CD4+IL-13+cells in peripheral blood well correlates with the severity of atopic dermatitis in children | Q57629030 | ||
Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense | Q61959753 | ||
The structure of normal skin and the morphology of atopic eczema | Q67816093 | ||
Increased chemokinetic and chemotactic responses of eosinophils in asthmatic patients | Q67980992 | ||
Glucocorticoids inhibit eosinophil responses to granulocyte-macrophage colony-stimulating factor | Q70190226 | ||
Peripheral eosinophil counts as a marker of disease activity in intrinsic and extrinsic asthma | Q70907709 | ||
Activation of human eosinophils by IL-13. Induction of CD69 surface antigen, its relationship to messenger RNA expression, and promotion of cellular viability | Q71403566 | ||
Relationship of plasma epinephrine and circulating eosinophils to nocturnal asthma | Q72269142 | ||
Vesicular transport of peroxidase in human eosinophilic myelocytes | Q72359721 | ||
Piecemeal degranulation of peripheral blood eosinophils: a study of allergic subjects during and out of the pollen season | Q73038102 | ||
The effect of corticosteroid therapy on blood eosinophils and eosinophilic cationic protein in patients with acute and chronic asthma | Q73090427 | ||
Interleukin-13 but not interleukin-4 prolongs eosinophil survival and induces eosinophil chemotaxis | Q73325019 | ||
Increased eotaxin-mRNA expression in non-atopic and atopic nasal polyps: comparison to RANTES and MCP-3 expression | Q74415878 | ||
IL-13 induces eosinophil recruitment into the lung by an IL-5- and eotaxin-dependent mechanism | Q74599784 | ||
Tissue eosinophilia in acute and chronic atopic dermatitis: a morphometric approach using quantitative image analysis of immunostaining | Q77331786 | ||
Glucocorticosteroids inhibit mRNA expression for eotaxin, eotaxin-2, and monocyte-chemotactic protein-4 in human airway inflammation with eosinophilia | Q78025450 | ||
Circulating eosinophils in asthma, allergic rhinitis, and atopic dermatitis lack morphological signs of degranulation | Q81379055 | ||
IL-4 and TNF-alpha increased the secretion of eotaxin from cultured fibroblasts of nasal polyps with eosinophil infiltration | Q81486555 | ||
Peripheral blood eosinophilia in atopic dermatitis | Q81574880 | ||
Profiling the dysregulated genes of keratinocytes in atopic dermatitis patients: cDNA microarray and interactomic analyses | Q83212683 | ||
Human asthma phenotypes: from the clinic, to cytokines, and back again | Q36079964 | ||
Evaluation of airway inflammation by quantitative Th1/Th2 cytokine mRNA measurement in sputum of asthma patients. | Q36148739 | ||
Peripheral blood eosinophil counts and bronchial responsiveness | Q36167650 | ||
Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo | Q36369717 | ||
How are T(H)2-type immune responses initiated and amplified? | Q36394985 | ||
Regulation of Th2 differentiation and Il4 locus accessibility. | Q36427376 | ||
Comparative transcriptomic analyses of atopic dermatitis and psoriasis reveal shared neutrophilic inflammation. | Q36437966 | ||
Protective immune mechanisms in helminth infection | Q36481763 | ||
Asthma: defining of the persistent adult phenotypes | Q36578781 | ||
A phase II placebo-controlled study of tralokinumab in moderate-to-severe asthma | Q36579400 | ||
Constitutive and allergen-induced expression of eotaxin mRNA in the guinea pig lung | Q36717272 | ||
Eosinophil adoptive transfer system to directly evaluate pulmonary eosinophil trafficking in vivo | Q36762460 | ||
Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients | Q36765753 | ||
α(M)β(2) integrin-mediated adhesion and motility of IL-5-stimulated eosinophils on periostin. | Q36842950 | ||
Eosinophils in innate immunity: an evolving story | Q36921021 | ||
Transcriptome Analysis Reveals Distinct Gene Expression Profiles in Eosinophilic and Noneosinophilic Chronic Rhinosinusitis with Nasal Polyps | Q36928471 | ||
Cytokine modulation of atopic dermatitis filaggrin skin expression | Q37159649 | ||
IL-13 as a therapeutic target for respiratory disease | Q37172858 | ||
T-helper type 2-driven inflammation defines major subphenotypes of asthma. | Q37343774 | ||
Gene expression patterns of Th2 inflammation and intercellular communication in asthmatic airways | Q37694606 | ||
Mepolizumab and exacerbations of refractory eosinophilic asthma | Q37711391 | ||
Eosinophil protein in airway macrophages: a novel biomarker of eosinophilic inflammation in patients with asthma | Q37711405 | ||
Understanding eosinophilic esophagitis: the cellular and molecular mechanisms of an emerging disease | Q37828058 | ||
Eosinophilic esophagitis: rapidly emerging disorder | Q37981624 | ||
Targeting eosinophils in allergy, inflammation and beyond | Q38075409 | ||
Eosinophils as diagnostic tools in chronic lung disease. | Q38077795 | ||
ACG clinical guideline: Evidenced based approach to the diagnosis and management of esophageal eosinophilia and eosinophilic esophagitis (EoE). | Q38097271 | ||
Noninvasive biomarkers that predict treatment benefit from biologic therapies in asthma. | Q38169245 | ||
Primary lysis of eosinophils in severe desquamative asthma | Q38170561 | ||
Effect of Subcutaneous Dupilumab on Nasal Polyp Burden in Patients With Chronic Sinusitis and Nasal Polyposis: A Randomized Clinical Trial | Q38396364 | ||
The Eosinophil in Infection | Q38675311 | ||
Asthma guidelines: the Global Initiative for Asthma in relation to national guidelines | Q38766362 | ||
Histopathologic features of eosinophilic esophagitis and eosinophilic gastrointestinal diseases | Q39195375 | ||
Dupilumab therapy provides clinically meaningful improvement in patient-reported outcomes (PROs): A phase IIb, randomized, placebo-controlled, clinical trial in adult patients with moderate to severe atopic dermatitis (AD). | Q39705730 | ||
Th2 cytokines act on S100/A11 to downregulate keratinocyte differentiation | Q39995471 | ||
A Mathematical Modeling Approach to Understanding the Effect of Anti-Interleukin Therapy on Eosinophils | Q40067123 | ||
Neurotrophic tyrosine kinase receptor 1 is a direct transcriptional and epigenetic target of IL-13 involved in allergic inflammation. | Q40590626 | ||
Efficacy and safety of tralokinumab in patients with severe uncontrolled asthma: a randomised, double-blind, placebo-controlled, phase 2b trial. | Q40672713 | ||
Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial | Q40693199 | ||
Endogenous antimicrobial peptides and skin infections in atopic dermatitis | Q40698186 | ||
Induction of the IL-13 receptor alpha2-chain by IL-4 and IL-13 in human keratinocytes: involvement of STAT6, ERK and p38 MAPK pathways. | Q40762484 | ||
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production | Q40849898 | ||
Eosinophilic esophagitis-linked calpain 14 is an IL-13-induced protease that mediates esophageal epithelial barrier impairment. | Q40961367 | ||
Prevalence of nasal polyps and its risk factors: Korean National Health and Nutrition Examination Survey 2009-2011. | Q41580602 | ||
Human eosinophils | Q41603736 | ||
Th2 cytokines associated with chronic rhinosinusitis with polyps down-regulate the antimicrobial immune function of human sinonasal epithelial cells | Q42732599 | ||
Topical delivery of interleukin-13 antisense oligonucleotides with cationic elastic liposome for the treatment of atopic dermatitis | Q42806432 | ||
Coordinate interaction between IL-13 and epithelial differentiation cluster genes in eosinophilic esophagitis. | Q42935186 | ||
Transgenic expression of interleukin-13 in the skin induces a pruritic dermatitis and skin remodeling | Q43183078 | ||
Total and specific IgE in nasal polyps is related to local eosinophilic inflammation | Q43570349 | ||
Comparative toxicity of purified human eosinophil granule proteins for newborn larvae of Trichinella spiralis. | Q43961318 | ||
Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. | Q44247874 | ||
Dupilumab in persistent asthma with elevated eosinophil levels | Q44480181 | ||
Relative importance of IL-4 and IL-13 in lesional skin of atopic dermatitis | Q44795743 | ||
Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics | Q44863693 | ||
Intravenous anti-IL-13 mAb QAX576 for the treatment of eosinophilic esophagitis | Q45003326 | ||
Endogenously expressed IL-13Rα2 attenuates IL-13-mediated responses but does not activate signaling in human lung fibroblasts | Q46373486 | ||
Rhinosinusitis: developing guidance for clinical trials | Q46506806 | ||
Efficacy and safety of lebrikizumab in patients with uncontrolled asthma (LAVOLTA I and LAVOLTA II): replicate, phase 3, randomised, double-blind, placebo-controlled trials. | Q46547661 | ||
Expression microarray analysis identifies novel epithelial-derived protein markers in eosinophilic esophagitis | Q46844547 | ||
Cytokine milieu of atopic dermatitis, as compared to psoriasis, skin prevents induction of innate immune response genes | Q47640250 | ||
Sputum and bronchial submucosal IL-13 expression in asthma and eosinophilic bronchitis. | Q47897731 | ||
A critical role for eosinophils in allergic airways remodeling | Q47925478 | ||
Defining a link with asthma in mice congenitally deficient in eosinophils. | Q47925494 | ||
IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells | Q50335900 | ||
Morphological changes in eosinophils are reliable markers of the severity of an acute asthma exacerbation in children. | Q50928137 | ||
High blood eosinophil count is associated with more frequent asthma attacks in asthma patients. | Q51247351 | ||
P921 | main subject | asthma | Q35869 |
P304 | page(s) | 139 | |
P577 | publication date | 2017-09-19 | |
P1433 | published in | Frontiers in Medicine | Q27726181 |
P1476 | title | Interleukin-13 in Asthma and Other Eosinophilic Disorders | |
P478 | volume | 4 |
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