| scholarly article | Q13442814 |
| P2093 | author name string | Dong Zu | |
| Kensuke Hirasawa | |||
| Sarah M Battcock | |||
| Thaddeus W Collier | |||
| P2860 | cites work | Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2 | Q24315658 |
| MxA GTPase blocks reporter gene expression of reconstituted Thogoto virus ribonucleoprotein complexes | Q24524303 | ||
| Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions | Q24532168 | ||
| The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus | Q24533256 | ||
| Antiviral actions of interferons | Q24550676 | ||
| The E3L gene of vaccinia virus encodes an inhibitor of the interferon-induced, double-stranded RNA-dependent protein kinase | Q24561643 | ||
| Interferon-induced human protein MxA is a GTPase which binds transiently to cellular proteins | Q24644756 | ||
| Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins | Q27860890 | ||
| ERK-1/2 activity is required for efficient RSV infection | Q40590486 | ||
| Oncogenic Ki-ras inhibits the expression of interferon-responsive genes through inhibition of STAT1 and STAT2 expression | Q40634782 | ||
| Chronic myeloid leukemia cells resistant to interferon-alpha lack STAT1 expression | Q40741810 | ||
| Oncolytic reovirus against ovarian and colon cancer. | Q40742634 | ||
| Oncogenes in Ras signalling pathway dictate host-cell permissiveness to herpes simplex virus 1. | Q40788613 | ||
| Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection | Q40863327 | ||
| Oncolytic activity of vesicular stomatitis virus is effective against tumors exhibiting aberrant p53, Ras, or myc function and involves the induction of apoptosis | Q40906922 | ||
| Treatment of myelogenous leukemia: current status and investigational options | Q40972574 | ||
| Regulation of Type I Interferon Gene Expression by Interferon Regulatory Factor-3 | Q41063455 | ||
| Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3gamma. | Q41082105 | ||
| Oncogenic ras induces an inhibitor of double-stranded RNA-dependent eukaryotic initiation factor 2 alpha-kinase activation | Q41594253 | ||
| Effect of cellular density and viral oncogenes on the major histocompatibility complex class I antigen response to gamma-interferon in BALB-c/3T3 cells. | Q41746686 | ||
| Signal Transduction through MAP Kinase Cascades | Q41750250 | ||
| Defective translational control facilitates vesicular stomatitis virus oncolysis | Q42831942 | ||
| A genetically engineered influenza A virus with ras-dependent oncolytic properties | Q45734706 | ||
| Mx proteins: mediators of innate resistance to RNA viruses | Q47932415 | ||
| Increasing complexity of Ras signaling | Q53429989 | ||
| Defective Jak-STAT signal transduction pathway in melanoma cells resistant to growth inhibition by interferon-alpha | Q58450536 | ||
| Extracellular HIV-1 Tat protein differentially activates the JNK and ERK/MAPK pathways in CD4 T cells | Q60704682 | ||
| Ras-dependent oncolysis with an adenovirus VAI mutant | Q64377417 | ||
| Interferon-alpha produces sustained cytogenetic responses in chronic myelogenous leukemia. Philadelphia chromosome-positive patients | Q70112862 | ||
| The role of MKK1/2 kinase activity in human cytomegalovirus infection | Q73426889 | ||
| How cells respond to interferons | Q27861006 | ||
| Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade | Q27863694 | ||
| PKR; a sentinel kinase for cellular stress | Q28137774 | ||
| Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta | Q28511740 | ||
| Mek2 is dispensable for mouse growth and development | Q28609344 | ||
| PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo | Q28609356 | ||
| Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase | Q29616448 | ||
| Viruses and interferons | Q29620788 | ||
| Inhibitory activity for the interferon-induced protein kinase is associated with the reovirus serotype 1 sigma 3 protein | Q33659093 | ||
| Interferon regulatory factors: the next generation | Q33753039 | ||
| Cytokines and JAK-STAT signaling | Q33783480 | ||
| Both carboxy- and amino-terminal domains of the vaccinia virus interferon resistance gene, E3L, are required for pathogenesis in a mouse model | Q33835582 | ||
| Understanding Ras: 'it ain't over 'til it's over'. | Q33877218 | ||
| Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus | Q33908950 | ||
| Signal transduction pathways and the modification of chromatin structure | Q34047826 | ||
| The virus battles: IFN induction of the antiviral state and mechanisms of viral evasion | Q34234077 | ||
| Coxsackievirus B3 replication is reduced by inhibition of the extracellular signal-regulated kinase (ERK) signaling pathway | Q34333784 | ||
| Visna Virus-Induced Activation of MAPK Is Required for Virus Replication and Correlates with Virus-Induced Neuropathology | Q34358595 | ||
| Mechanism of interferon action: Phosphorylation of protein synthesis initiation factor eIF-2 in interferon-treated human cells by a ribosome-associated kinase processing site specificity similar to hemin-regulated rabbit reticulocyte kinase | Q34555781 | ||
| The interferon antiviral response: from viral invasion to evasion | Q34641791 | ||
| Cytokine therapeutics: lessons from interferon alpha | Q35033232 | ||
| Development of recombinant vesicular stomatitis viruses that exploit defects in host defense to augment specific oncolytic activity | Q35182301 | ||
| Reversal of the interferon-sensitive phenotype of a vaccinia virus lacking E3L by expression of the reovirus S4 gene. | Q35830193 | ||
| The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA- | Q35964369 | ||
| Signaling pathways in Ras-mediated tumorigenicity and metastasis. | Q36219180 | ||
| Mx proteins: GTPases involved in the interferon-induced antiviral state | Q36673730 | ||
| Reovirus oncolysis: the Ras/RalGEF/p38 pathway dictates host cell permissiveness to reovirus infection | Q37285576 | ||
| Interferon induces a unique protein in mouse cells bearing a gene for resistance to influenza virus | Q37607765 | ||
| The 2-5A system: a personal view | Q38181395 | ||
| Cleavage of RasGAP and phosphorylation of mitogen-activated protein kinase in the course of coxsackievirus B3 replication | Q39550258 | ||
| MEK-specific inhibitor U0126 blocks spread of Borna disease virus in cultured cells | Q39602816 | ||
| The Herpes Simplex Virus Type 2 R1 Protein Kinase (ICP10 PK) Blocks Apoptosis in Hippocampal Neurons, Involving Activation of the MEK/MAPK Survival Pathway | Q39682246 | ||
| Effect of p38 Mitogen-Activated Protein Kinase on the Replication of Encephalomyocarditis Virus | Q39748972 | ||
| Possible role of macrophage-derived soluble mediators in the pathogenesis of encephalomyocarditis virus-induced diabetes in mice. | Q39879496 | ||
| MEK1 and MEK2, different regulators of the G1/S transition. | Q40530177 | ||
| Raf promotes human herpesvirus-8 (HHV-8/KSHV) infection. | Q40560220 | ||
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 4422-4430 | |
| P577 | publication date | 2006-05-01 | |
| P1433 | published in | Journal of Virology | Q1251128 |
| P1476 | title | Negative regulation of the alpha interferon-induced antiviral response by the Ras/Raf/MEK pathway | |
| P478 | volume | 80 |
| Q54650268 | A novel MEK2/PI3Kδ pathway controls the expression of IL-1 receptor antagonist in IFN-β-activated human monocytes. |
| Q41359622 | Activated Ras/MEK inhibits the antiviral response of alpha interferon by reducing STAT2 levels |
| Q35689692 | Activation of the Ras/Raf/MEK Pathway Facilitates Hepatitis C Virus Replication via Attenuation of the Interferon-JAK-STAT Pathway |
| Q97543614 | After Nf1 loss in Schwann cells, inflammation drives neurofibroma formation |
| Q45400013 | Analysis of differently expressed proteins and transcripts in gills of Penaeus vannamei after yellow head virus infection |
| Q39212798 | Cancer upregulated gene 2, a novel oncogene, confers resistance to oncolytic vesicular stomatitis virus through STAT1-OASL2 signaling |
| Q37157958 | Colorectal clinical trials: what is on the horizon? |
| Q38394291 | Contribution of Human Fibroblasts and Endothelial Cells to the Hallmarks of Inflammation as Determined by Proteome Profiling |
| Q55427397 | Current understanding of reovirus oncolysis mechanisms. |
| Q59352746 | Defects in interferon pathways as potential biomarkers of sensitivity to oncolytic viruses |
| Q38513218 | Differential host gene expression in cells infected with highly pathogenic H5N1 avian influenza viruses |
| Q33508793 | Differential regulation of type I interferon and epidermal growth factor pathways by a human Respirovirus virulence factor |
| Q35040110 | Effect of human activated NRAS on replication of delNS1 H5N1 influenza virus in MDCK cells |
| Q37564490 | Engineering oncolytic viruses to exploit tumor specific defects in innate immune signaling pathways |
| Q37565269 | Epidermal growth factor receptor inhibitors trigger a type I interferon response in human skin. |
| Q92014001 | Genetic Programs Driving Oncogenic Transformation: Lessons from in Vitro Models |
| Q40411967 | Global gene analysis identifying genes commonly regulated by the Ras/Raf/MEK and type I IFN pathways |
| Q40067130 | H-Ras Exerts Opposing Effects on Type I Interferon Responses Depending on Its Activation Status |
| Q30437260 | IFN-beta-induced alteration of VSV protein phosphorylation in neuronal cells. |
| Q36100040 | IRF1 Downregulation by Ras/MEK Is Independent of Translational Control of IRF1 mRNA. |
| Q40119647 | Influence of calcium/calmodulin on budding of Ebola VLPs: implications for the involvement of the Ras/Raf/MEK/ERK pathway |
| Q58180308 | Late activation of the Raf/MEK/ERK pathway is required for translocation of the respiratory syncytial virus F protein to the plasma membrane and efficient viral replication |
| Q104495267 | MEK reduces cancer-specific PpIX accumulation through the RSK-ABCB1 and HIF-1α-FECH axes |
| Q37135340 | Making sense of current and emerging therapies in pancreatic cancer: balancing benefit and value |
| Q34158123 | Measles virus suppresses RIG-I-like receptor activation in dendritic cells via DC-SIGN-mediated inhibition of PP1 phosphatases |
| Q36125975 | Mitogen-activated Protein Kinase Kinase 2 (MEK2), a Novel E2-interacting Protein, Promotes the Growth of Classical Swine Fever Virus via Attenuation of the JAK-STAT Signaling Pathway. |
| Q42273321 | Modulation of apoptosis by V protein mumps virus. |
| Q92547206 | Novel Function of Bluetongue Virus NS3 Protein in Regulation of the MAPK/ERK Signaling Pathway |
| Q38944907 | Oncogenic Ras inhibits IRF1 to promote viral oncolysis |
| Q33924550 | Oncolytic virotherapy: molecular targets in tumor-selective replication and carrier cell-mediated delivery of oncolytic viruses |
| Q33743847 | Permissiveness of human cancer cells to oncolytic bovine herpesvirus 1 is mediated in part by KRAS activity |
| Q37247071 | RNA viruses and the mitogenic Raf/MEK/ERK signal transduction cascade |
| Q40141506 | Ras transformation mediates reovirus oncolysis by enhancing virus uncoating, particle infectivity, and apoptosis-dependent release |
| Q36188447 | Ras transformation results in cleavage of reticulon protein Nogo-B that is associated with impairment of IFN response |
| Q30413201 | Regulatory, biosafety and safety challenges for novel cells as substrates for human vaccines |
| Q40613951 | Repression of CD24 surface protein expression by oncogenic Ras is relieved by inhibition of Raf but not MEK or PI3K. |
| Q79176708 | STAT1-independent inhibition of cyclooxygenase-2 expression by IFNgamma; a common pathway of IFNgamma-mediated gene repression but not gene activation |
| Q90727444 | Starvation and Pseudo-Starvation as Drivers of Cancer Metastasis through Translation Reprogramming |
| Q36960705 | Stimulation of Ebola virus production from persistent infection through activation of the Ras/MAPK pathway |
| Q34412329 | Suppression of IFN-Induced Transcription Underlies IFN Defects Generated by Activated Ras/MEK in Human Cancer Cells |
| Q52769266 | The Continued Promise and Many Disappointments of Oncolytic Virotherapy in Gastrointestinal Malignancies |
| Q37374645 | The IKK-related kinases: from innate immunity to oncogenesis |
| Q28079490 | The Importance of Physiologically Relevant Cell Lines for Studying Virus-Host Interactions |
| Q40444191 | The Interaction Between Human Papillomaviruses and the Stromal Microenvironment |
| Q40132472 | The RAS/Raf1/MEK/ERK signaling pathway facilitates VSV-mediated oncolysis: implication for the defective interferon response in cancer cells |
| Q37978889 | The Role of Signal Transducer and Activator of Transcription-2 in the Interferon Response |
| Q35876239 | Treating Tumors With a Vaccinia Virus Expressing IFNβ Illustrates the Complex Relationships Between Oncolytic Ability and Immunogenicity |
| Q51846287 | Tumor Restrictions to Oncolytic Virus |
| Q57469278 | Unscheduled HDAC4 repressive activity in human fibroblasts triggers TP53-dependent senescence and favours cell transformation |
| Q27489886 | Up-Regulation of Hepatitis C Virus Replication and Production by Inhibition of MEK/ERK Signaling |
| Q39318787 | Viral exploitation of the MEK/ERK pathway - A tale of vaccinia virus and other viruses |
| Q36684458 | Viral gene therapy |
| Q36750723 | Viral suppression of the interferon system |
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