| scholarly article | Q13442814 |
| P50 | author | Robert J Williams | Q53998014 |
| Anna K Clark | Q56860619 | ||
| Stephen B. McMahon | Q29653464 | ||
| Marzia Malcangio | Q39184027 | ||
| P2093 | author name string | Anthony H Dickenson | |
| John Grist | |||
| Sophie Pezet | |||
| Fabien Marchand | |||
| Richard D'Mello | |||
| P2860 | cites work | The phosphoinositide 3-kinase pathway | Q27860738 |
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| Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity. | Q51432094 | ||
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| A common thread for pain and memory synapses? Brain-derived neurotrophic factor and trkB receptors. | Q35082160 | ||
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| Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization. | Q42468083 | ||
| ERK MAP kinase activation in superficial spinal cord neurons induces prodynorphin and NK-1 upregulation and contributes to persistent inflammatory pain hypersensitivity. | Q42515491 | ||
| Phosphatidylinositol 3-kinase is a central mediator of NMDA receptor signalling to MAP kinase (Erk1/2), Akt/PKB and CREB in striatal neurones. | Q43922344 | ||
| Calcium-calmodulin-dependent protein kinase II contributes to spinal cord central sensitization. | Q43999204 | ||
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| Gene knockdown with intrathecal siRNA of NMDA receptor NR2B subunit reduces formalin-induced nociception in the rat. | Q45095142 | ||
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| Evidence for spinal N-methyl-D-aspartate receptor involvement in prolonged chemical nociception in the rat. | Q45267214 | ||
| Increase of phosphorylation of calcium/calmodulin-dependent protein kinase-II in several brain regions by substance P administered intrathecally in mice | Q46440062 | ||
| Acute ethanol inhibits extracellular signal-regulated kinase, protein kinase B, and adenosine 3':5'-cyclic monophosphate response element binding protein activity in an age- and brain region-specific manner | Q46440626 | ||
| PI3 kinase signaling is required for retrieval and extinction of contextual memory | Q46529350 | ||
| Insulin modulates hippocampal activity-dependent synaptic plasticity in a N-methyl-d-aspartate receptor and phosphatidyl-inositol-3-kinase-dependent manner | Q46644037 | ||
| Activation of protein kinase B/Akt signaling pathway contributes to mechanical hypersensitivity induced by capsaicin | Q46855694 | ||
| Systemic morphine suppresses noxious stimulus-evoked Fos protein-like immunoreactivity in the rat spinal cord | Q46919018 | ||
| Evidence for localized release of substance P within rat spinal cord evoked by physiological and electrical stimuli | Q47562229 | ||
| Involvement of phosphorylated Ca2+/calmodulin-dependent protein kinase II and phosphorylated extracellular signal-regulated protein in the mouse formalin pain model | Q48464099 | ||
| Contribution of bradykinin to heat-induced substance P release in the hind instep of rats. | Q50766572 | ||
| P433 | issue | 16 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | inflammation | Q101991 |
| central sensitization | Q21087540 | ||
| P304 | page(s) | 4261-4270 | |
| P577 | publication date | 2008-04-01 | |
| P1433 | published in | Journal of Neuroscience | Q1709864 |
| P1476 | title | Phosphatidylinositol 3-kinase is a key mediator of central sensitization in painful inflammatory conditions | |
| P478 | volume | 28 |
| Q37998860 | AMPA receptor trafficking in inflammation-induced dorsal horn central sensitization |
| Q50927511 | Activation of PI3Kγ/Akt pathway mediates bone cancer pain in rats. |
| Q42131127 | Activation of cytosolic phospholipase A2 in dorsal root ganglion neurons by Ca2+/calmodulin-dependent protein kinase II after peripheral nerve injury |
| Q37268022 | Acute inhibition of Ca2+/calmodulin-dependent protein kinase II reverses experimental neuropathic pain in mice |
| Q46868460 | An overview of pathways encoding nociception |
| Q36936701 | Antinociceptive Effect of Tephrosia sinapou Extract in the Acetic Acid, Phenyl-p-benzoquinone, Formalin, and Complete Freund's Adjuvant Models of Overt Pain-Like Behavior in Mice. |
| Q35834031 | Carrageenan induced phosphorylation of Akt is dependent on neurokinin-1 expressing neurons in the superficial dorsal horn |
| Q37361185 | Central sensitization: a generator of pain hypersensitivity by central neural plasticity |
| Q36107446 | Chemocentric informatics approach to drug discovery: identification and experimental validation of selective estrogen receptor modulators as ligands of 5-hydroxytryptamine-6 receptors and as potential cognition enhancers |
| Q34510177 | Construction of a global pain systems network highlights phospholipid signaling as a regulator of heat nociception |
| Q34025889 | Differential distribution of PI3K isoforms in spinal cord and dorsal root ganglia: potential roles in acute inflammatory pain |
| Q33816612 | Dorsal horn alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor trafficking in inflammatory pain |
| Q34732967 | Downregulation of PI3Kcb utilizing adenovirus-mediated transfer of siRNA attenuates bone cancer pain. |
| Q42408881 | ERK-GluR1 phosphorylation in trigeminal spinal subnucleus caudalis neurons is involved in pain associated with dry tongue |
| Q35791944 | Effects of Electroacupuncture on N-Methyl-D-aspartate Receptor-Related Signaling Pathway in the Spinal Cord of Normal Rats |
| Q35986155 | Endogenous BDNF augments NMDA receptor phosphorylation in the spinal cord via PLCγ, PKC, and PI3K/Akt pathways during colitis |
| Q37425758 | Endogenous PI3K/Akt and NMDAR act independently in the regulation of CREB activity in lumbosacral spinal cord in cystitis |
| Q64089955 | Epiregulin is released from intervertebral disks and induces spontaneous activity in pain pathways |
| Q41442652 | Formaldehyde up-regulates TRPV1 through MAPK and PI3K signaling pathways in a rat model of bone cancer pain |
| Q41315226 | Formalin-induced behavioural hypersensitivity and neuronal hyperexcitability are mediated by rapid protein synthesis at the spinal level |
| Q37772543 | Glutamate receptor phosphorylation and trafficking in pain plasticity in spinal cord dorsal horn |
| Q36731871 | Glutaminase Increases in Rat Dorsal Root Ganglion Neurons after Unilateral Adjuvant-Induced Hind Paw Inflammation |
| Q37694411 | Hippocampal AMPARs involve the central sensitization of rats with irritable bowel syndrome |
| Q35058604 | In vivo regulation of brain-derived neurotrophic factor in dorsal root ganglia is mediated by nerve growth factor-triggered Akt activation during cystitis |
| Q38835644 | Inflammation-induced GluA1 trafficking and membrane insertion of Ca2+ permeable AMPA receptors in dorsal horn neurons is dependent on spinal tumor necrosis factor, PI3 kinase and protein kinase A. |
| Q37624494 | Ionotropic glutamate receptors in spinal nociceptive processing. |
| Q27023075 | Lipid kinases as therapeutic targets for chronic pain |
| Q30482277 | MAP kinase and pain |
| Q34398500 | Mammalian target of rapamycin signaling in the spinal cord is required for neuronal plasticity and behavioral hypersensitivity associated with neuropathy in the rat. |
| Q33584232 | Maternal hypothyroxinemia impairs spatial learning and synaptic nature and function in the offspring |
| Q64907937 | Microglial BDNF, PI3K, and p-ERK in the Spinal Cord Are Suppressed by Pulsed Radiofrequency on Dorsal Root Ganglion to Ease SNI-Induced Neuropathic Pain in Rats. |
| Q37052031 | NR2B-selective conantokin peptide inhibitors of the NMDA receptor display enhanced antinociceptive properties compared to non-selective conantokins |
| Q41531549 | Neurokinin 1 receptor-expressing projection neurons in laminae III and IV of the rat spinal cord have synaptic AMPA receptors that contain GluR2, GluR3 and GluR4 subunits |
| Q40762287 | Neurotrophic factor changes in the rat thick skin following chronic constriction injury of the sciatic nerve |
| Q64901127 | Opioid receptors inhibit the spinal AMPA receptor Ca2+ permeability that mediates latent pain sensitization. |
| Q48535002 | PI3-kinase/Akt pathway-regulated membrane insertion of acid-sensing ion channel 1a underlies BDNF-induced pain hypersensitivity |
| Q34373966 | PI3K contributed to modulation of spinal nociceptive information related to ephrinBs/EphBs |
| Q42414570 | PI3K mediated activation of GSK-3β reduces at-level primary afferent growth responses associated with excitotoxic spinal cord injury dysesthesias |
| Q53093145 | PI3K/Akt Pathway is Required for Spinal Central Sensitization in Neuropathic Pain. |
| Q90324754 | Pellino1 regulates neuropathic pain as well as microglial activation through the regulation of MAPK/NF-κB signaling in the spinal cord |
| Q33814688 | Peripheral inflammation induces tumor necrosis factor dependent AMPA receptor trafficking and Akt phosphorylation in spinal cord in addition to pain behavior |
| Q38648002 | Perturbing PSD-95 interactions with NR2B-subtype receptors attenuates spinal nociceptive plasticity and neuropathic pain. |
| Q92317820 | Post-surgical inhibition of phosphatidylinositol 3-kinase attenuates the plantar incision-induced postoperative pain behavior via spinal Akt activation in male mice |
| Q41462899 | Primary Blast-Induced Changes in Akt and GSK3β Phosphorylation in Rat Hippocampus. |
| Q34275621 | Proteomic identification of altered cerebral proteins in the complex regional pain syndrome animal model. |
| Q45060820 | Regulation of transient receptor potential cation channel subfamily V1 protein synthesis by the phosphoinositide 3-kinase/Akt pathway in colonic hypersensitivity |
| Q34135685 | SA14867, a newly synthesized kappa-opioid receptor agonist with antinociceptive and antipruritic effects |
| Q48309913 | Single high-concentration capsaicin application prevents c-Fos expression in spinothalamic and postsynaptic dorsal column neurons after surgical incision |
| Q35658338 | Specific involvement of atypical PKCζ/PKMζ in spinal persistent nociceptive processing following peripheral inflammation in rat. |
| Q34127181 | Spinal cord protein interacting with C kinase 1 is required for the maintenance of complete Freund's adjuvant-induced inflammatory pain but not for incision-induced post-operative pain |
| Q34989480 | Spinal phosphinositide 3-kinase-Akt-mammalian target of rapamycin signaling cascades in inflammation-induced hyperalgesia |
| Q37723223 | Synaptic plasticity and pain: role of ionotropic glutamate receptors. |
| Q38051560 | Systems biology approaches to finding novel pain mediators |
| Q33668659 | Targeting the Microglial Signaling Pathways: New Insights in the Modulation of Neuropathic Pain |
| Q30156856 | The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment |
| Q24288817 | The search for novel analgesics: targets and mechanisms |
| Q92587789 | Translation regulation in the spinal dorsal horn - A key mechanism for development of chronic pain |
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