Modulation of autoimmunity by treatment of an infectious disease

scientific article published on 7 May 2007

Modulation of autoimmunity by treatment of an infectious disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.00423-07
P932PMC publication ID1932944
P698PubMed publication ID17485457
P5875ResearchGate publication ID6346873

P2093author name stringJuan S Leon
David M Engman
Kenneth V Hyland
Melvin D Daniels
Nick Giafis
Kegiang Wang
Thomas J Bahk
LaKitta M Woods
P2860cites workTrypanosoma cruzi: antibodies to a MAP-like protein in chronic Chagas' disease cross-react with mammalian cytoskeletonQ33481437
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Comparative efficacies of TAK-187, a long-lasting ergosterol biosynthesis inhibitor, and benznidazole in preventing cardiac damage in a murine model of Chagas' diseaseQ33722151
Aspects of cytotoxic T cell memoryQ41091852
Anti-CD4 abrogates rejection and reestablishes long-term tolerance to syngeneic newborn hearts grafted in mice chronically infected with Trypanosoma cruziQ41823109
Parasite persistence correlates with disease severity and localization in chronic Chagas' diseaseQ42605133
T-cell molecular mimicry in Chagas disease: identification and partial structural analysis of multiple cross-reactive epitopes between Trypanosoma cruzi B13 and cardiac myosin heavy chainQ42653469
Etiology of Chagas disease myocarditis: autoimmunity, parasite persistence, or both?Q43890969
Experimental chemotherapy against Trypanosoma cruzi infection: essential role of endogenous interferon-gamma in mediating parasitologic cureQ44116597
Use of a purified Trypanosoma cruzi antigen and CpG oligodeoxynucleotides for immunoprotection against a lethal challenge with trypomastigotesQ44646613
Increased susceptibility of Stat4-deficient and enhanced resistance in Stat6-deficient mice to infection with Trypanosoma cruziQ44684713
Progress towards interruption of transmission of Chagas diseaseQ44910717
Experimental chronic Chagas' disease myocarditis is an autoimmune disease preventable by induction of immunological tolerance to myocardial antigensQ45169566
Antibodies to beta 1 and beta 2 adrenoreceptors in Chagas' diseaseQ46161530
Humoral autoimmune response to ribosomal P proteins in chronic Chagas heart diseaseQ47870383
Treatment of experimental chronic chagas disease with trifluralinQ48707094
Interleukin-4 biases differentiation of B cells from Trypanosoma cruzi-infected mice and restrains their fratricide: role of Fas ligand down-regulation and MHC class II-transactivator up-regulation.Q52008485
Trypanosoma cruzi: serum antibody reactivity to the parasite antigens in susceptible and resistant mice.Q54321039
Trypanosoma cruzi DNA in cardiac lesions of Argentinean patients with end-stage chronic chagas heart disease.Q54727747
Changes in cell populations and immunoglobulin-producing cells in the spleens of mice infected with Trypanosoma cruzi: Correlations with parasite-specific antibody responseQ57203314
Chagas' diseaseQ58844005
Cardiac antigen-specific autoantibody production is associated with cardiomyopathy in Trypanosoma cruzi-infected miceQ58844027
Xid-associated resistance to experimental Chagas' disease is IFN-gamma dependentQ58844145
Microvascular changes as a cause of chronic cardiomyopathy in Chagas' diseaseQ58845107
Myosin autoimmunity is not essential for cardiac inflammation in acute Chagas' diseaseQ58845899
Soluble platelet selectin (sP-selectin) and soluble vascular cell adhesion molecule-1 (sVCAM-1) decrease during therapy with benznidazole in children with indeterminate form of Chagas' diseaseQ58846997
In-vivo treatment with benznidazole enhances phagocytosis, parasite destruction and cytokine release by macrophages during infection with a drug-susceptible but not with a derived drug-resistant Trypansoma cruzi populationQ58847063
Secretion by Trypanosoma cruzi of a hemolysin active at low pHQ69060121
Molecular mimicry and autoimmune diseaseQ69205630
Chronic chagasic tissue lesions in the absence of Trypanosoma cruzi: a proposed mechanismQ80381485
Cardiac parasympathetic abnormalities: Cause or consequence of chagas heart disease?Q80818267
Cellular autoimmunity to cardiac myosin in patients with a recent myocardial infarctionQ81595089
Virus-specific and bystander CD8 T cells recruited during virus-induced encephalomyelitisQ33724194
Cardiac myosin autoimmunity in acute Chagas' heart diseaseQ34009000
Role of neurotransmitter autoantibodies in the pathogenesis of chagasic peripheral dysautonomia.Q34196250
Parasite persistence in the aetiology of Chagas diseaseQ34240113
Benznidazole treatment following acute Trypanosoma cruzi infection triggers CD8+ T-cell expansion and promotes resistance to reinfectionQ34252265
Autoimmunity in Chagas disease cardiopathy: biological relevance of a cardiac myosin-specific epitope crossreactive to an immunodominant Trypanosoma cruzi antigen.Q34453015
The pathogenesis of Chagas' disease: when autoimmune and parasite-specific immune responses meet.Q34463172
Pathogenesis of Chagas heart disease: role of autoimmunityQ34500622
Autoimmunity in Chagas' disease: specific inhibition of reactivity of CD4+ T cells against myosin in mice chronically infected with Trypanosoma cruzi.Q35101438
The significance of autoimmunity in the pathogenesis of chagas heart diseaseQ35109331
Autoimmunity and molecular mimicry in the pathogenesis of post streptococcal heart diseaseQ35109368
Identification of major Trypanosoma cruzi antigenic determinants in chronic Chagas' heart diseaseQ35162429
Molecular mimicry between Trypanosoma cruzi and host nervous tissuesQ35246043
Chagas disease: a role for autoimmunity?Q35547443
Life-spans of human T-cell responses to determinants from the circumsporozoite proteins of Plasmodium falciparum and Plasmodium vivaxQ35554701
Specific chemotherapy of Chagas disease: controversies and advancesQ35569069
Parasitic diseases of the heartQ35650927
T cell mimicry in inflammatory heart diseaseQ35704727
Autoimmunity in chagas disease cardiomyopathy: Fulfilling the criteria at last?Q35846112
Longevity of the immune response and memory to blood-stage malaria infection.Q36304674
Fl-160. A surface antigen of Trypanosoma cruzi that mimics mammalian nervous tissueQ36356249
Mimicry in Trypanosoma cruzi: fantasy and realityQ36845308
Do self-heart-reactive T cells expand in Trypanosoma cruzi-immune hosts?Q37005726
Human infection with Trypanosoma cruzi induces parasite antigen-specific cytotoxic T lymphocyte responsesQ37385100
Molecular mimicry by Trypanosoma cruzi: the F1-160 epitope that mimics mammalian nerve can be mapped to a 12-amino acid peptideQ37545197
Rapid quantitation of Trypanosoma cruzi in host tissue by real-time PCR.Q38957765
Antigen-specific T cells maintain an effector memory phenotype during persistent Trypanosoma cruzi infectionQ39218496
Chagas disease: current epidemiological trends after the interruption of vectorial and transfusional transmission in the Southern Cone countriesQ39262265
Antibodies to an epitope from the Cha human autoantigen are markers of Chagas' disease.Q39508836
Trypanosoma Cruzi-Sensitized T-Lymphocyte Mediated 51Cr Release from Human Heart Cells in Chagas' Disease *Q39522787
Interleukin-12 enhances in vivo parasiticidal effect of benznidazole during acute experimental infection with a naturally drug-resistant strain of Trypanosoma cruziQ39559044
Autoimmunity in Chagas' disease. Identification of cardiac myosin-B13 Trypanosoma cruzi protein crossreactive T cell clones in heart lesions of a chronic Chagas' cardiomyopathy patientQ39772057
Free Radical Metabolites in the Mode of Action of Chemotherapeutic Agents and Phagocytic Cells on Trypanosoma cruziQ40142374
A cardiac myosin-specific autoimmune response is induced by immunization with Trypanosoma cruzi proteinsQ40882932
Benznidazole, a drug employed in the treatment of Chagas' disease, down-regulates the synthesis of nitrite and cytokines by murine stimulated macrophagesQ40919170
Molecular mimicry between cardiac myosin and Trypanosoma cruzi antigen B13: identification of a B13-driven human T cell clone that recognizes cardiac myosin.Q41052780
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectinfectious diseaseQ18123741
P304page(s)3641-3650
P577publication date2007-05-07
P1433published inInfection and ImmunityQ6029193
P1476titleModulation of autoimmunity by treatment of an infectious disease
P478volume75

Reverse relations

cites work (P2860)
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Q43623255DNA repair BER pathway inhibition increases cell death caused by oxidative DNA damage in Trypanosoma cruzi.
Q41552272Depletion of regulatory T cells decreases cardiac parasitosis and inflammation in experimental Chagas disease
Q39836484Effect of a combination DNA vaccine for the prevention and therapy of Trypanosoma cruzi infection in mice: role of CD4+ and CD8+ T cells
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Q36901969Etiological treatment of chronic Chagas disease: neglected 'evidence' by evidence-based medicine
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Q92765270Low-Level Parasite Persistence Drives Vasculitis and Myositis in Skeletal Muscle of Mice Chronically Infected with Trypanosoma cruzi
Q26858780Mechanisms of Trypanosoma cruzi persistence in Chagas disease
Q42554282Monocyte activation by necrotic cells is promoted by mitochondrial proteins and formyl peptide receptors
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