Differential potencies of cocaine and its metabolites, cocaethylene and benzoylecgonine, in suppressing the functional expression of somatostatin and neuropeptide Y producing neurons in cultures of fetal cortical cells

scientific article published on August 1997

Differential potencies of cocaine and its metabolites, cocaethylene and benzoylecgonine, in suppressing the functional expression of somatostatin and neuropeptide Y producing neurons in cultures of fetal cortical cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0006-2952(97)00202-5
P698PubMed publication ID9313776

P2093author name stringHo RH
Aguila-Mansilla N
Little BB
Barnea A
P2860cites workNeuropeptide Y Distribution in the Rat BrainQ34247574
Cocaine inhibition of ligand binding at dopamine, norepinephrine and serotonin transporters: a structure-activity studyQ34307279
Cocaine and cocaethylene: microdialysis comparison of brain drug levels and effects on dopamine and serotoninQ34730741
Cocaethylene is more potent than cocaine in mediating lethalityQ34982819
Cocaethylene: a unique cocaine metabolite displays high affinity for the dopamine transporterQ35011052
Biochemical differentiation of aggregating cell cultures of different fetal rat brain regionsQ39164019
Molecular, functional and biochemical characteristics of the dopamine transporter: regional differences and clinical relevanceQ40735817
Pharmacological characterization of dopaminergic influence on expression of neuropeptide Y immunoreactivity by rat striatal neuronsQ41391649
Cocaine neurotoxicity and altered neuropeptide Y immunoreactivity in the rat hippocampus; a silver degeneration and immunocytochemical studyQ42288347
Dynamic dopaminergic regulation of neuropeptide Y systems in discrete striatal and accumbens regionsQ42491131
A comparison of somatostatin and neuropeptide Y distribution in monkey brainQ43949979
Ultrastructural features of NPY-containing neurons in the rat striatumQ44049745
Regulated production and secretion of immunoreactive neuropeptide Y by aggregating fetal brain cells in culturesQ44171320
Enhanced rate of expression and biosynthesis of neuropeptide Y after kainic acid-induced seizuresQ44483678
Neuronal interactions between neuropeptide Y (NPY) and catecholaminergic systems in the rat arcuate nucleus as shown by dual immunocytochemistryQ44999676
Effect of prenatal and postnatal cocaine exposure on somatostatin content and binding in frontoparietal cortex and hippocampus of developing rat pupsQ45103172
Development of somatostatin immunoreactive neurons in the rat occipital cortex: a combined immunocytochemical-autoradiographic studyQ48120095
Colocalization of binding sites for somatostatin, muscarine and nicotine on cultured neurones of rat neocortex, cerebellum, brain stem and spinal cord: combined autoradiographic and immunohistochemical studiesQ48121564
Inhibition of muscarinic receptor-stimulated phosphoinositide metabolism by cocaine, norcocaine and cocaethylene in rat brainQ48123335
An early and transient period of protein synthesis is required for induction of neuropeptide Y-mRNA by phorbol ester and forskolin in aggregate cultures of fetal brain cellsQ48245318
Long-term cocaine administration is not neurotoxic to cultured fetal mesencephalic dopamine neuronsQ48300824
A comparison of regional somatostatin and neuropeptide Y distribution in rat striatum and brainQ48321566
Distribution of neuropeptide Y-like immunoreactivity in the rat central nervous system--II. Immunohistochemical analysisQ48324021
Regulation of neuropeptide expression in cultured cerebral cortical neurons by brain-derived neurotrophic factorQ48343104
Structural requirements for cocaine congeners to interact with dopamine and serotonin uptake sites in mouse brain and to induce stereotyped behaviorQ48356432
GABAergic neurons of the rat dorsal hippocampus express muscarinic acetylcholine receptorsQ48381874
Colocalization of neuropeptide Y immunoreactivity in brainstem catecholaminergic neurons that project to the paraventricular nucleus of the hypothalamusQ48436589
The anatomy of neuropeptide-Y-containing neurons in rat brainQ48466172
Hippocampal neuropeptide Y mRNA is reduced in a strain of learned helpless resistant ratsQ48477159
Dexamethasone-Induced Accumulation of Neuropeptide-Y by Aggregating Fetal Brain Cells in Culture: A Process Dependent on the Developmental Age of the Aggregates*Q48685218
Characterization of [3H]dopamine uptake sites and [3H]cocaine recognition sites in primary cultures of mesencephalic neurons during in vitro developmentQ48711157
Development of neuropeptide Y (NPY) immunoreactive neurons in the rat occipital cortex: a combined immunohistochemical-autoradiographic studyQ48932415
Neuropeptide-Y-immunoreactive innervation of thyrotropin-releasing hormone-synthesizing neurons in the rat hypothalamic paraventricular nucleusQ49013511
Effects of acute and chronic cocaine administration on somatostatin level and binding in the rat brainQ49014076
Drug screening of meconium in infants of drug-dependent mothers: an alternative to urine testing.Q51749582
Protracted elimination of cocaine metabolites in long-term high-dose cocaine abusers.Q51763924
Neuropeptide Y and peptide YY as possible cerebrospinal fluid markers for major depression and schizophrenia, respectivelyQ52071642
Brain-derived neurotrophic factor induces functional expression and phenotypic differentiation of cultured fetal neuropeptide Y-producing neurons.Q52204503
Cholinergic and GABAergic neurons in the rat medial septum express muscarinic acetylcholine receptors.Q52215422
Light-microscopic immunocytochemical localization of tyrosine hydroxylase in prenatal rat brain. I. Early ontogenyQ52293274
Substance P immunoreactivity in the median eminence of the North American opossum and domestic fowl.Q53961262
A simple, rapid, and sensitive DNA assay procedureQ56879279
Expression of neuropeptide Y immunoreactivity in the rat nucleus accumbens is under the influence of the dopaminergic mesencephalic pathwayQ62031248
Differential co-existence of neuropeptide Y (NPY)-like immunoreactivity with catecholamines in the central nervous system of the ratQ64217912
Somatostatin-like immunoreactivity in rat main olfactory bulb: extent of coexistence with neuropeptide Y-, tyrosine hydroxylase- and vitamin D-dependent calcium binding protein-like immunoreactivitiesQ69375116
Coexistence of somatostatin with neuropeptide Y, but not with cholecystokinin or vasoactive intestinal peptide, in neurons of the rat amygdalaQ69377634
Neuropeptide Y-like immunoreactivity in neurons of the solitary tract nuclei: vesicular localization and synaptic input from GABAergic terminalsQ69579351
Expression of tyrosine hydroxylase in neurons of cultured cerebral cortex: evidence for phenotypic plasticity in neurons of the CNSQ69898193
Concomitant increase of somatostatin, neuropeptide Y and glutamate decarboxylase in the frontal cortex of rats with decreased seizure thresholdQ69925268
The increase in striatal neuropeptide Y immunoreactivity induced by neonatal dopamine-depleting lesions in rats is reversed by intrastriatal dopamine-rich transplantsQ72368151
Light-microscopic immunocytochemical localization of tyrosine hydroxylase in prenatal rat brain. II. Late ontogenyQ72481900
Morphological differentiation of neuropeptide Y neurons in aggregate cultures of dissociated fetal cortical cells: a model system for glia-neuron paracrine interactionsQ72691772
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)491-500
P577publication date1997-08-01
P1433published inBiochemical PharmacologyQ864229
P1476titleDifferential potencies of cocaine and its metabolites, cocaethylene and benzoylecgonine, in suppressing the functional expression of somatostatin and neuropeptide Y producing neurons in cultures of fetal cortical cells
P478volume54

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cites work (P2860)
Q89575924A role for the neuropeptide somatostatin in the neurobiology of behaviors associated with substances abuse and affective disorders
Q33717138Alcohol, slow wave sleep, and the somatotropic axis
Q34486271Evidence for a synergistic effect of the HIV-1 envelope protein gp120 and brain-derived neurotrophic factor (BDNF) leading to enhanced expression of somatostatin neurons in aggregate cultures derived from the human fetal cortex
Q30439481Gene profiling the response to repeated cocaine self-administration in dorsal striatum: a focus on circadian genes

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