A role for the neuropeptide somatostatin in the neurobiology of behaviors associated with substances abuse and affective disorders

scientific article published on 03 February 2020

A role for the neuropeptide somatostatin in the neurobiology of behaviors associated with substances abuse and affective disorders is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1016/J.NEUROPHARM.2020.107983
P932PMC publication ID7080567
P698PubMed publication ID32027909

P2093author name stringTodd E Thiele
Stacey L Robinson
P2860cites workHeterogeneity and diversity of striatal GABAergic interneuronsQ21090474
Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidneyQ24337883
Cloning and characterization of a fourth human somatostatin receptorQ24563011
Neurotransmitters of the suprachiasmatic nucleiQ25257183
Somatostatin and Somatostatin-Containing Neurons in Shaping Neuronal Activity and PlasticityQ26738420
The Current Status of Somatostatin-Interneurons in Inhibitory Control of Brain Function and PlasticityQ26741113
The role of brain somatostatin receptor 2 in the regulation of feeding and drinking behaviorQ28085083
Somatostatin and its receptor familyQ28141222
Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressantsQ28271841
Sweetener preference of C57BL/6ByJ and 129P3/J miceQ28351955
Interneurons of the neocortical inhibitory systemQ29547509
Tripartite synapses: glia, the unacknowledged partnerQ29615224
Somatostatin Depresses the Excitability of Subicular Bursting Cells: Roles of Inward Rectifier K+ Channels, KCNQ channels and EpacQ30101028
Central Amygdala Somatostatin Neurons Gate Passive and Active Defensive Behaviors.Q30367905
Comparison of the activation of somatostatin- and neuropeptide Y-containing neuronal populations of the rat amygdala following two different anxiogenic stressorsQ30447711
Predator stress induces behavioral inhibition and amygdala somatostatin receptor 2 gene expressionQ30485379
Experience-dependent modification of a central amygdala fear circuit.Q30536522
Opposing effects of acute versus chronic blockade of frontal cortex somatostatin-positive inhibitory neurons on behavioral emotionality in miceQ30584304
Disinhibition of somatostatin-positive GABAergic interneurons results in an anxiolytic and antidepressant-like brain stateQ30848010
The role of the neuropeptide somatostatin on methamphetamine and glutamate-induced neurotoxicity in the striatum of miceQ33575312
Activation of Brain Somatostatin Signaling Suppresses CRF Receptor-Mediated Stress ResponseQ33600238
Suprachiasmatic nucleus: the brain's circadian clockQ33766862
Methamphetamine-induced cell death: selective vulnerability in neuronal subpopulations of the striatum in miceQ33899756
Advances in understanding neuronal somatostatin receptorsQ33927953
Alcohol and depressionQ34025976
Hypothalamic Polypeptide That Inhibits the Secretion of Immunoreactive Pituitary Growth HormoneQ34216319
Reduced somatostatin in subgenual anterior cingulate cortex in major depressionQ34574517
Somatostatin, neuronal vulnerability and behavioral emotionalityQ35163769
The forced swim test as a model of depressive-like behaviorQ35458705
Molecular evidence for BDNF- and GABA-related dysfunctions in the amygdala of female subjects with major depressionQ35613219
Delineating somatostatin's neuronal actionsQ35743693
GABA-related transcripts in the dorsolateral prefrontal cortex in mood disordersQ36073289
The somatostatin sst1 receptor: an autoreceptor for somatostatin in brain and retina?Q36308100
Chronic mild stress alters the somatostatin receptors in the rat brainQ36427074
Neurochemical regulation of sleepQ36507719
Mechanisms of somatostatin-evoked responses in neurons of the rat lateral amygdalaQ49017369
Somatostatin as a trophic factor. Analysis of transgenic mice overexpressing somatostatin in astrocytesQ49053729
Low levels of somatostatin in human CSF mark depressive episodesQ49096077
sst2-receptor gene deletion exacerbates chronic stress-induced deficits: Consequences for emotional and cognitive ageingQ50057757
Anxiolytic and antidepressant actions of somatostatin: the role of sst2 and sst3 receptors.Q50737277
Circuit dissection of the role of somatostatin in itch and pain.Q51732949
Hippocampal SSTR4 somatostatin receptors control the selection of memory strategies.Q51955825
Alcohol use disorders and depression--the chicken or the egg?Q52298479
Selective coexpression of multiple chemical markers defines discrete populations of neocortical GABAergic neurons.Q53276503
Behavioral response to imipramine under chronic mild stress corresponds with increase of mRNA encoding somatostatin receptors sst2 and sst4 expression in medial habenular nucleusQ57040016
Astrocytes detect and upregulate transmission at inhibitory synapses of somatostatin interneurons onto pyramidal cellsQ57471948
Somatostatin receptorsQ58448612
Transcriptional and physiological adaptations in nucleus accumbens somatostatin interneurons that regulate behavioral responses to cocaineQ58796051
A Central Extended Amygdala Circuit That Modulates AnxietyQ59417088
A quantitative autoradiographical study on the distribution of somatostatin sst2 receptors in the rat central nervous system using [125I]-BIM-23027Q60717694
Viral labeling of neurons synaptically connected to nucleus accumbens somatostatin interneuronsQ64123140
N-terminally extended somatostatin: the primary structure of somatostatin-28Q71132613
Phase advances of circadian rhythms in somatostatin depleted rats: effects of cysteamine on rhythms of locomotor activity and electrical discharge of the suprachiasmatic nucleusQ72374565
Effect of somatostatin on circadian rhythms of firing and 2-deoxyglucose uptake in rat suprachiasmatic slicesQ72657983
Distribution, targeting, and internalization of the sst4 somatostatin receptor in rat brainQ73770850
Somatostatin administration alters taste preferences in the ratQ77720305
A circadian rhythm of somatostatin messenger RNA levels, but not of vasoactive intestinal polypeptide/peptide histidine isoleucine messenger RNA levels in rat suprachiasmatic nucleusQ84900316
Genetic Activation, Inactivation, and Deletion Reveal a Limited And Nuanced Role for Somatostatin-Containing Basal Forebrain Neurons in Behavioral State ControlQ88595413
A Non-Canonical Cortico-Amygdala Inhibitory LoopQ90068460
Chronic ethanol exposure alters prelimbic prefrontal cortical Fast-Spiking and Martinotti interneuron function with differential sex specificity in rat brainQ90565000
GABA and glutamate neurons in the VTA regulate sleep and wakefulnessQ90597124
Somatostatin Gene and Protein Expression in the Non-human Primate Central Extended AmygdalaQ90899648
Hippocampal-Evoked Feedforward Inhibition in the Nucleus AccumbensQ91302882
CRF modulation of central monoaminergic function: Implications for sex differences in alcohol drinking and anxietyQ91454720
The center of the emotional universe: Alcohol, stress, and CRF1 amygdala circuitryQ91471677
Loss of Glutamate Decarboxylase 67 in Somatostatin-Expressing Neurons Leads to Anxiety-Like Behavior and Alteration in the Akt/GSK3β Signaling PathwayQ91637407
Prefrontal somatostatin interneurons encode fear memoryQ92026070
Driving the Downward Spiral: Alcohol-Induced Dysregulation of Extended Amygdala Circuits and Negative AffectQ92561641
Morphine coordinates SST and PV interneurons in the prelimbic cortex to disinhibit pyramidal neurons and enhance rewardQ92625031
Genetic Relationships Between Ethanol-Induced Conditioned Place Aversion and Other Ethanol Phenotypes in 15 Inbred Mouse StrainsQ92753016
Alcohol use disorder and sleep disturbances: a feed-forward allostatic frameworkQ92988501
Opioid signal transduction regulates the dendritic morphology of somatostatin and parvalbumin interneurons in the medial prefrontal cortexQ92997864
Central somatostatin signaling and regulation of food intakeQ93010331
In Vitro Optogenetic Characterization of Neuropeptide Release from Prefrontal Cortical Somatostatin NeuronsQ93124295
Endogenous circadian rhythmicity of somatostatin like-immunoreactivity in the rat suprachiasmatic nucleusQ48319274
In vivo release of somatostatin from rat hippocampus and striatumQ48347187
CSF somatostatin in Alzheimer's disease and major depression: relationship to hypothalamic-pituitary-adrenal axis and clinical measuresQ48389238
Roles of Hippocampal Somatostatin Receptor Subtypes in Stress Response and EmotionalityQ48392547
Increase in somatostatin immunoreactivity in the suprachiasmatic nucleus of aged Wistar ratsQ48430151
Somatostatin potently stimulates in vivo striatal dopamine and gamma-aminobutyric acid release by a glutamate-dependent actionQ48497506
des-AA-1,2,5[D-Trp8, IAmp9]somatostatin-14 allows the identification of native rat somatostatin sst1 receptor subtypeQ48563195
Circadian rhythms of somatostatin-immunoreactivity in the suprachiasmatic nucleus of the ratQ48674743
Involvement of sst2 somatostatin receptor in locomotor, exploratory activity and emotional reactivity in mice.Q48700093
Somatostatin inhibits excitatory transmission at rat hippocampal synapses via presynaptic receptors.Q48703336
Striatal neurons containing both somatostatin- and avian pancreatic polypeptide (APP)-like immunoreactivities and NADPH-diaphorase activity: A light and electron microscopic studyQ48792880
Effects of acute and chronic ethanol administration and its withdrawal on the level and binding of somatostatin in rat brainQ48874103
Modest long-term ethanol consumption affects expression of neurotransmitter receptor genes in the rat nucleus accumbensQ48874820
Expression of five somatostatin receptor mRNAs in the human brain and pituitaryQ48905833
Somatostatin neurons form a distinct peptidergic neuronal group in the rat suprachiasmatic nucleus: a double labeling in situ hybridization studyQ48919192
Altered neuropeptide concentrations in cerebrospinal fluid of psychiatric patientsQ48954318
Effects of acute and chronic cocaine administration on somatostatin level and binding in the rat brainQ49014076
???Q58117606
Role of the somatostatin system in contextual fear memory and hippocampal synaptic plasticityQ36575490
Ethanol consumption and taste preferences in C57BL/6ByJ and 129/J miceQ36800702
Elicited hippocampal theta rhythm: a screen for anxiolytic and procognitive drugs through changes in hippocampal function?Q36925126
Somatostatinergic systems in brain: networks and functionsQ36998583
Major depression and comorbid substance use disorders.Q37087213
Stress differentially alters mu opioid receptor density and trafficking in parvalbumin-containing interneurons in the female and male rat hippocampusQ37185035
The cholinergic forebrain arousal system acts directly on the circadian pacemaker.Q37451113
Somatostatin, Alzheimer's disease and cognition: an old story coming of age?Q37549147
Somatostatin sst2 receptor knock-out mice: localisation of sst1-5 receptor mRNA and binding in mouse brain by semi-quantitative RT-PCR, in situ hybridisation histochemistry and receptor autoradiography.Q38291094
Chronobiology of ethanol: animal modelsQ38478034
Somatostatin-expressing neurons in cortical networks.Q38844277
Basolateral to Central Amygdala Neural Circuits for Appetitive BehaviorsQ38882478
Somatostatin-Positive Gamma-Aminobutyric Acid Interneuron Deficits in Depression: Cortical Microcircuit and Therapeutic PerspectivesQ39429092
Treatment of panic-like attacks with a long-acting analogue of somatostatin.Q39517962
Hypothalamic peptides: central nervous system control of visceral functions.Q40085050
Molecular Biology of Somatostatin ReceptorsQ40431999
Somatostatin receptor subtype 4 activation is involved in anxiety and depression-like behavior in mouse models.Q40521512
Activation of brain somatostatin 2 receptors stimulates feeding in mice: analysis of food intake microstructureQ41813746
Treatment of Comorbid Alcohol Dependence and Anxiety Disorder: Review of the Scientific Evidence and Recommendations for Treatment.Q42072894
Somatostatin inhibits interleukin 6 release from rat cortical type I astrocytes via the inhibition of adenylyl cyclaseQ42440122
Differential potencies of cocaine and its metabolites, cocaethylene and benzoylecgonine, in suppressing the functional expression of somatostatin and neuropeptide Y producing neurons in cultures of fetal cortical cellsQ42444861
Somatostatin augments long-term potentiation of the mossy fiber-CA3 system in guinea-pig hippocampal slicesQ42464819
Basal forebrain circuit for sleep-wake control.Q42483601
Acute stress and dexamethasone rapidly increase hippocampal somatostatin synthesis and release from the dentate gyrus hilusQ42509420
Chronic desipramine treatment selectively potentiates somatostatin-induced dopamine release in the nucleus accumbensQ42510108
Characterization of the glutamate receptors mediating release of somatostatin from cultured hippocampal neuronsQ42512685
Relative expression of mRNA for the somatostatin receptors in the caudate putamen of C57BL/6J and 129P3/J mice: strain and heroin effectsQ42608034
Hippocampal sst(1) receptors are autoreceptors and do not affect seizures in ratsQ43172339
Effect of neuropeptide Y (NPY) on oral ethanol intake in Wistar, alcohol-preferring (P), and -nonpreferring (NP) ratsQ43567210
CSF monoamine metabolites and somatostatin in Alzheimer's disease and major depressionQ43870990
Differential gene expression in the rat caudate putamen after "binge" cocaine administration: advantage of triplicate microarray analysisQ44398440
Childhood Adversities are not a Predictors of SSTR4met in AlcoholicsQ45127400
Anxiolytic and antidepressant effects of intracerebroventricularly administered somatostatin: behavioral and neurophysiological evidence.Q46305778
Differential effects of ethanol ingestion on somatostatin content, somatostatin receptors and adenylyl cyclase activity in the frontoparietal cortex of virgin and parturient rats.Q46566402
Higher susceptibility of somatostatin 4 receptor gene-deleted mice to chronic stress-induced behavioral and neuroendocrine alterations.Q47346667
Organization of Valence-Encoding and Projection-Defined Neurons in the Basolateral Amygdala.Q47828372
Amygdala interneuron subtypes control fear learning through disinhibitionQ47877725
Injections of the somatostatin receptor type 2 agonist L-054,264 into the amygdala block expression but not acquisition of conditioned fear in ratsQ47914979
The anxiolytic effects of somatostatin following intra-septal and intra-amygdalar microinfusions are reversed by the selective sst2 antagonist PRL2903.Q48019066
Cloning and expression of a novel mouse somatostatin receptor (SSTR2B).Q48152351
Effects of sequential removal of rats from a group cage, and of individual housing of rats, on substance P, cholecystokinin and somatostatin levels in the periaqueductal grey and limbic regionsQ48152970
Differential expression of messenger RNAs for somatostatin receptor subtypes SSTR1, SSTR2 and SSTR3 in adult rat brain: analysis by RNA blotting and in situ hybridization histochemistryQ48160167
Chronic stress reduces the number of GABAergic interneurons in the adult rat hippocampus, dorsal-ventral and region-specific differencesQ48188691
Neural Mechanisms of Circadian Regulation of Natural and Drug RewardQ48189294
P921main subjectneurobiologyQ2728012
P304page(s)107983
P577publication date2020-02-03
P1433published inNeuropharmacologyQ15332439
P1476titleA role for the neuropeptide somatostatin in the neurobiology of behaviors associated with substances abuse and affective disorders
P478volume167

Search more.