Elevated D-glucose induces insulin insensitivity in human umbilical endothelial cells isolated from gestational diabetic pregnancies

scientific article published on January 1998

Elevated D-glucose induces insulin insensitivity in human umbilical endothelial cells isolated from gestational diabetic pregnancies is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1469-7793.1998.219BX.X
P932PMC publication ID2230704
P698PubMed publication ID9481683
P5875ResearchGate publication ID13749325

P2093author name stringL Sobrevia
D L Yudilevich
G E Mann
P2860cites workInsulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide releaseQ34185006
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Glucose-induced phosphorylation of the insulin receptor. Functional effects and characterization of phosphorylation sitesQ37351595
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Gestational diabetes: a challenge for the futureQ40813864
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The coupling of glucose metabolism and perfusion in human skeletal muscle. The potential role of endothelium-derived nitric oxideQ40928164
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The retinal blood flow in diabetesQ41782102
Release of endothelium-derived relaxing factor from pig cultured aortic endothelial cells, as assessed by changes in endothelial cell cyclic GMP content, is inhibited by a phorbol esterQ41981742
Functional differentiation of the vascular endothelium in high risk pregnanciesQ42033787
Impaired arginine metabolism and NO synthesis in coronary endothelial cells of the spontaneously diabetic BB rat.Q42474627
Effect of Insulin on Acetylcholine-Induced Vasodilation in Normotensive Subjects and Patients With Essential HypertensionQ42479408
High Glucose Condition Desensitizes Insulin Action at the Levels of Receptor KinaseQ42480027
Diabetes-induced activation of system y+ and nitric oxide synthase in human endothelial cells: association with membrane hyperpolarizationQ42514958
Activation of L-arginine transport (system y+) and nitric oxide synthase by elevated glucose and insulin in human endothelial cells.Q42519401
Regulation of L-arginine transport and nitric oxide release in superfused porcine aortic endothelial cellsQ42521287
Protein kinase C activation alters the sensitivity of agonist-stimulated endothelial-cell prostacyclin production to intracellular Ca2+.Q42802617
Human endothelial cells are defective in diabetic vascular diseaseQ46555838
High D-glucose-induced changes in endothelial Ca2+/EDRF signaling are due to generation of superoxide anions.Q54140931
The effect of metabolic control on hemodynamics in short-term insulin-dependent diabetic patients.Q54353577
Skin blood cell flux in insulin-dependent diabetic subjects in relation to retinopathy or incipient nephropathyQ68090862
Regulatory effects of insulin and experimental diabetes on neutral amino acid transport in the perfused rat exocrine pancreas. Kinetics of unidirectional L-serine influx and efflux at the basolateral plasma membraneQ70509796
Glomerular Filtration Rate and Renal Plasma Flow in Short-term and Long-term Juvenile Diabetes MellitusQ70531581
Insulin stimulates cationic amino acid transport activity in the isolated perfused rat pancreasQ70860721
Activation of the sodium-potassium pump contributes to insulin-induced vasodilation in humansQ71506852
Chronic hyperglycemia impairs endothelial function and insulin sensitivity via different mechanisms in insulin-dependent diabetes mellitusQ71571202
Activation of endothelial cells during insulin-dependent diabetes mellitus: a biochemical and morphological studyQ71669572
TNF-stimulated arginine transport by human vascular endothelium requires activation of protein kinase CQ71692744
Inhibitory effects of insulin on cytosolic Ca2+ level and contraction in the rat aorta. Endothelium-dependent and -independent mechanismsQ71730178
Adenosine transport in cultured human umbilical vein endothelial cells is reduced in diabetesQ72101317
Insulin's effect on protein kinase C and diacylglycerol induced by diabetes and glucose in vascular tissuesQ72761827
Diabetes and insulin-induced stimulation of L-arginine transport and nitric oxide synthesis in rabbit isolated gastric glandsQ73112822
Prostaglandins and nitric oxide mediate insulin-induced vasodilation in the human forearmQ73499535
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
preproinsulinQ7240673
P304page(s)219-230
P577publication date1998-01-01
P1433published inJournal of PhysiologyQ7743612
P1476titleElevated D-glucose induces insulin insensitivity in human umbilical endothelial cells isolated from gestational diabetic pregnancies
P478volume506 ( Pt 1)

Reverse relations

cites work (P2860)
Q41856075Accelerated intimal hyperplasia and increased endogenous inhibitors for NO synthesis in rabbits with alloxan-induced hyperglycaemia
Q64248655Anti-inflammatory Role of Carotenoids in Endothelial Cells Derived from Umbilical Cord of Women Affected by Gestational Diabetes Mellitus
Q36776710Chronic hyperglicemia and nitric oxide bioavailability play a pivotal role in pro-atherogenic vascular modifications.
Q37333473Gestational diabetes mellitus impairs Nrf2-mediated adaptive antioxidant defenses and redox signaling in fetal endothelial cells in utero
Q58477477HUVECs from newborns with a strong family history of diabetes show diminished ROS synthesis in the presence of high glucose concentrations
Q47393927Human supraphysiological gestational weight gain and fetoplacental vascular dysfunction
Q37854853Impact of dietary soy isoflavones in pregnancy on fetal programming of endothelial function in offspring
Q92481688Inositol and antioxidant supplementation: Safety and efficacy in pregnancy
Q26749697Insulin Is a Key Modulator of Fetoplacental Endothelium Metabolic Disturbances in Gestational Diabetes Mellitus
Q35043443Insulin restores gestational diabetes mellitus-reduced adenosine transport involving differential expression of insulin receptor isoforms in human umbilical vein endothelium
Q46693415L-arginine uptake in normal and diabetic rat retina and retinal pigment epithelium.
Q28343381Modulation of adenosine transport by insulin in human umbilical artery smooth muscle cells from normal or gestational diabetic pregnancies
Q34137628Pathological aspects of lipid peroxidation.
Q37854856Placental vascular dysfunction in diabetic pregnancies: intimations of fetal cardiovascular disease?
Q73300504Regulation of adenosine transport by D-glucose in human fetal endothelial cells: involvement of nitric oxide, protein kinase C and mitogen-activated protein kinase
Q35035933Regulation of amino acid and glucose transporters in endothelial and smooth muscle cells
Q37958772The placenta and gestational diabetes mellitus.