Analyzing the protease web in skin: meprin metalloproteases are activated specifically by KLK4, 5 and 8 vice versa leading to processing of proKLK7 thereby triggering its activation

scientific article

Analyzing the protease web in skin: meprin metalloproteases are activated specifically by KLK4, 5 and 8 vice versa leading to processing of proKLK7 thereby triggering its activation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1515/BC.2010.023
P698PubMed publication ID20128684

P50authorChristoph Becker-PaulyQ47008760
P2093author name stringViktor Magdolen
Christoph Becker-Pauly
Anke Ohler
Susanne Wagner
Mekdes Debela
P2860cites workStructure of homo- and hetero-oligomeric meprin metalloproteases. Dimers, tetramers, and high molecular mass multimersQ28210655
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)455-460
P577publication date2010-04-01
P1433published inBiological ChemistryQ4914948
P1476titleAnalyzing the protease web in skin: meprin metalloproteases are activated specifically by KLK4, 5 and 8 vice versa leading to processing of proKLK7 thereby triggering its activation
P478volume391

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cites work (P2860)
Q42906891Doxycycline indirectly inhibits proteolytic activation of tryptic kallikrein-related peptidases and activation of cathelicidin
Q34077651Enhanced activity of meprin-α, a pro-migratory and pro-angiogenic protease, in colorectal cancer
Q33715944Kallikrein-related peptidase-8 (KLK8) is an active serine protease in human epidermis and sweat and is involved in a skin barrier proteolytic cascade
Q38182526Mapping orphan proteases by proteomics: meprin metalloproteases deciphered as potential therapeutic targets
Q36836257Meprin A metalloproteinase and its role in acute kidney injury
Q24302283Meprins process matrix metalloproteinase-9 (MMP-9)/gelatinase B and enhance the activation kinetics by MMP-3
Q36318836Meprinα transactivates the epidermal growth factor receptor (EGFR) via ligand shedding, thereby enhancing colorectal cancer cell proliferation and migration
Q35145029Metalloprotease meprin beta generates nontoxic N-terminal amyloid precursor protein fragments in vivo
Q37480184Metastasis of ovarian cancer is mediated by kallikrein related peptidases
Q51864651Morpholino knockdown of the ubiquitously expressed transmembrane serine protease TMPRSS4a in zebrafish embryos exhibits severe defects in organogenesis and cell adhesion.
Q34457491Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs).
Q34256463Protease-armed bacteria in the skin
Q52148357Proteolytic degradation of neuropeptide Y (NPY) from head to toe: Identification of novel NPY-cleaving peptidases and potential drug interactions in CNS and Periphery.
Q35264713Proteomic analyses reveal an acidic prime side specificity for the astacin metalloprotease family reflected by physiological substrates
Q38948393Putative functions of tissue kallikrein-related peptidases in vaginal fluid
Q33940892Role of meprins to protect ileal mucosa of Crohn's disease patients from colonization by adherent-invasive E. coli
Q27673367Structural basis for the sheddase function of human meprin   metalloproteinase at the plasma membrane
Q92651287Tethering soluble meprin α in an enzyme complex to the cell surface affects IBD-associated genes
Q39095782The Metalloprotease Meprin β Is an Alternative β-Secretase of APP.
Q38269341The biology and regulation of corneodesmosomes
Q36613779The metalloproteases meprin α and meprin β: unique enzymes in inflammation, neurodegeneration, cancer and fibrosis
Q36503385The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10.
Q36101228Toward an integrative analysis of the tumor microenvironment in ovarian epithelial carcinoma
Q38362486Unleashing the therapeutic potential of human kallikrein-related serine proteases

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