p53-R175H mutant gains new function in regulation of doxorubicin-induced apoptosis

scientific article published on April 2005

p53-R175H mutant gains new function in regulation of doxorubicin-induced apoptosis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/IJC.20818
P698PubMed publication ID15578696
P5875ResearchGate publication ID8148541

P2093author name stringFranz Y F Ho
Kwok-pui Fung
Siu-kai Kong
Tim-tak Kwok
Wing-pui Tsang
P2860cites workThe 1995 Walter Hubert Lecture--molecular epidemiology of human cancer: insights from the mutational analysis of the p53 tumour-suppressor geneQ36134953
Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expressionQ36551292
A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosisQ40019792
Restoration of the G1 checkpoint and the apoptotic pathway mediated by wild-type p53 sensitizes squamous cell carcinoma of the head and neck to radiotherapyQ41113431
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)331-336
P577publication date2005-04-01
P1433published inInternational Journal of CancerQ332492
P1476titlep53-R175H mutant gains new function in regulation of doxorubicin-induced apoptosis
P478volume114

Reverse relations

cites work (P2860)
Q28473504CHEK2 mutations affecting kinase activity together with mutations in TP53 indicate a functional pathway associated with resistance to epirubicin in primary breast cancer
Q35080476Cyclopentenyl cytosine induces senescence in breast cancer cells through the nucleolar stress response and activation of p53.
Q39572380Delayed caspase-8 activation and enhanced integrin β1-activated FAK underpins anoikis in oesophageal carcinoma cells harbouring mt p53-R175H.
Q42819037Differential effects of novel tumour-derived p53 mutations on the transformation of NIH-3T3 cells
Q35238838Epithelial-mesenchymal plasticity is a decisive feature for the metastatic outgrowth of disseminated WAP-T mouse mammary carcinoma cells
Q53741376GUARDIN is a p53-responsive long non-coding RNA that is essential for genomic stability.
Q48863873Gain of function of mutant TP53 in glioblastoma: prognosis and response to temozolomide
Q39602480Gambogic acid-induced degradation of mutant p53 is mediated by proteasome and related to CHIP.
Q39229754Mutant TP53 enhances the resistance of glioblastoma cells to temozolomide by up-regulating O(6)-methylguanine DNA-methyltransferase
Q46709821Mutant p53 gain of function: reduction of tumor malignancy of human cancer cell lines through abrogation of mutant p53 expression
Q38197826Mutant p53 in cancer: new functions and therapeutic opportunities
Q38846785Oncogenic Mutant p53 Gain of Function Nourishes the Vicious Cycle of Tumor Development and Cancer Stem-Cell Formation
Q55346775Plakoglobin restores tumor suppressor activity of p53R175H mutant by sequestering the oncogenic potential of β-catenin.
Q24310790Role of p53/FAK association and p53Ser46 phosphorylation in staurosporine-mediated apoptosis: wild type versus mutant p53-R175H
Q35785051Salmonella enterica serovar enteritidis modulates intestinal epithelial miR-128 levels to decrease macrophage recruitment via macrophage colony-stimulating factor
Q37411955Strategies for Molecularly Enhanced Chemotherapy to Achieve Synthetic Lethality in Endometrial Tumors with Mutant p53
Q35961417The isolation of an RNA aptamer targeting to p53 protein with single amino acid mutation.
Q35503066p53-dependent activation of microRNA-34a in response to etoposide-induced DNA damage in osteosarcoma cell lines not impaired by dominant negative p53 expression

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