Demonstration of urokinase expression in cancer cells of colon adenocarcinomas by immunohistochemistry and in situ hybridization

scientific article published on October 1999

Demonstration of urokinase expression in cancer cells of colon adenocarcinomas by immunohistochemistry and in situ hybridization is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0002-9440(10)65214-5
P932PMC publication ID1867004
P698PubMed publication ID10514394
P5875ResearchGate publication ID12786877

P2093author name stringY Xu
S N Sait
J L Bailey
G Markus
S R Harvey
R M Penetrante
P2860cites workAntigen levels of urokinase plasminogen activator and its receptor at the tumor-host interface of colorectal adenocarcinomas are related to tumor aggressivenessQ71739570
Immunohistochemical detection of the receptor for urokinase plasminogen activator in human colon cancerQ72416781
Regional variations of urokinase-type plasminogen activator in human colorectal cancer: a quantitative study by image analysisQ72427901
Plasminogen activator secretion of human tumors in short-term organ culture, including a comparison of primary and metastatic colon tumorsQ72711549
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activityQ26778490
Plasminogen activators, integrins, and the coordinated regulation of cell adhesion and migrationQ28610258
Plasminogen activation by receptor-bound urokinase. A kinetic study with both cell-associated and isolated receptorQ28646979
Fluorescent Probes as Tools to Assess the Receptor for the Urokinase-Type Plasminogen Activator on Tumor CellsQ33270106
Mapping of human chromosome Xq28 by two-color fluorescence in situ hybridization of DNA sequences to interphase cell nucleiQ35195845
Epitope-mapped monoclonal antibodies as tools for functional and morphological analyses of the human urokinase receptor in tumor tissueQ35764327
Plasminogen activators, tissue degradation, and cancerQ39476382
Proteolytic enzymes in cancer invasion and metastasisQ39506008
The relevance of plasminogen activators to neoplastic growth. A review of recent literature.Q39526019
Complementation between urokinase-producing and receptor-producing cells in extracellular matrix degradationQ40642836
Biology and biochemistry of proteinases in tumor invasion.Q40868702
Stromal cell expression of components of matrix-degrading protease systems in human cancer.Q41105738
The urokinase-type plasminogen activator system in cancer metastasis: A reviewQ41522331
Role of the urokinase receptor in facilitating extracellular matrix invasion by cultured colon cancerQ41674938
Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasive foci in human colon adenocarcinomasQ42131114
Immunohistochemical localization of urokinase- and tissue-type plasminogen activators in psoriatic skinQ42511607
Localization of urokinase-type plasminogen activator in stromal cells in adenocarcinomas of the colon in humansQ42756488
Determination of the levels of urokinase and its receptor in human colon carcinoma cell linesQ44582678
Secretion of plasminogen activators by human colorectal and gastric tumor explantsQ44802729
Expression and localization of urokinase-type plasminogen activator in human astrocytomas in vivoQ48088819
Immunolocalization of urokinase-type plasminogen activator in adenomas and carcinomas of the colorectum.Q52442794
Localization of plasminogen activators in human colon cancer by immunoperoxidase stainingQ69885785
Examination of urokinase protein/transcript levels and their relationship with laminin degradation in cultured colon carcinomaQ69938910
Location of plasminogen activator (PA) and PA inhibitor in human colorectal adenocarcinomasQ70750649
Human endothelial cells contain one type of plasminogen activatorQ70790411
Combined overexpression of urokinase, urokinase receptor, and plasminogen activator inhibitor-1 is associated with breast cancer progression: an immunohistochemical comparison of normal, benign, and malignant breast tissuesQ71089140
P4510describes a project that usesimmunohistochemistryQ899285
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectadenocarcinomaQ356033
immunohistochemistryQ899285
P304page(s)1115-1120
P577publication date1999-10-01
P1433published inThe American Journal of PathologyQ4744259
P1476titleDemonstration of urokinase expression in cancer cells of colon adenocarcinomas by immunohistochemistry and in situ hybridization
P478volume155

Reverse relations

cites work (P2860)
Q37452991A pilot study of urokinase-type plasminogen activator (uPA) overexpression in the brush cytology of patients with malignant pancreatic or biliary strictures
Q28218647Activation of human meprin-alpha in a cell culture model of colorectal cancer is triggered by the plasminogen-activating system
Q33254343Activity and expression of urokinase-type plasminogen activator and matrix metalloproteinases in human colorectal cancer
Q41465764Bacterial endotoxin enhances colorectal cancer cell adhesion and invasion through TLR-4 and NF-kappaB-dependent activation of the urokinase plasminogen activator system
Q52575847Elevated urokinase-specific surface receptor expression is maintained through its interaction with urokinase plasminogen activator.
Q35745865Expression of heparanase in normal, dysplastic, and neoplastic human colonic mucosa and stroma. Evidence for its role in colonic tumorigenesis
Q31087874Gelsolin induces colorectal tumor cell invasion via modulation of the urokinase-type plasminogen activator cascade
Q35681554High level of urokinase plasminogen activator contributes to cholangiocarcinoma invasion and metastasis
Q40784517High level synthesis of recombinant soluble urokinase receptor (CD87) by ovarian cancer cells reduces intraperitoneal tumor growth and spread in nude mice
Q28205781Increased expression of seprase, a membrane-type serine protease, is associated with lymph node metastasis in human colorectal cancer
Q43636939Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions
Q34425462The hemostatic system and angiogenesis in malignancy.
Q34343645The tumor microenvironment in colorectal carcinogenesis
Q57483483Usefulness of plasma D-dimer level for monitoring development of distant organ metastasis in colorectal cancer patients after curative resection

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