scholarly article | Q13442814 |
P50 | author | Luke Norton | Q51373612 |
Ralph A. DeFronzo | Q58689309 | ||
P2093 | author name string | W Hu | |
B Doiron | |||
P2860 | cites work | Phosphorylation of grb10 regulates its interaction with 14-3-3 | Q24295241 |
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak | Q24296478 | ||
Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains | Q24315001 | ||
Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14 | Q27656836 | ||
Localization of endogenous Grb10 to the mitochondria and its interaction with the mitochondrial-associated Raf-1 pool | Q28139493 | ||
Relationship between glucose tolerance, insulin secretion, and insulin action in non-obese individuals with varying degrees of glucose tolerance | Q46126827 | ||
Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration? | Q46736684 | ||
Capacity to secrete islet hormones after subtotal pancreatectomy for pancreatic cancer. | Q51601381 | ||
Reduced insulin secretion by subtotal pancreatectomy: preservation of insulin sensitivity and glucose tolerance in postoperative patients. | Q51615321 | ||
Selective β-Cell Loss and α-Cell Expansion in Patients with Type 2 Diabetes Mellitus in Korea | Q57214866 | ||
Glucoregulation during insulin and glucagon deficiency: role of catecholamines | Q72533926 | ||
Evidence against GRB10 as the gene responsible for Silver-Russell syndrome | Q74438203 | ||
A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance | Q77652485 | ||
Ablation of PDK1 in pancreatic beta cells induces diabetes as a result of loss of beta cell mass | Q83207600 | ||
Interaction of a GRB-IR splice variant (a human GRB10 homolog) with the insulin and insulin-like growth factor I receptors. Evidence for a role in mitogenic signaling | Q28289183 | ||
Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes | Q28506930 | ||
Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4 | Q28507095 | ||
Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy | Q30853783 | ||
Grb10 interacts with Bim L and inhibits apoptosis | Q33533399 | ||
Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation. | Q34059976 | ||
Major DNA fragmentation is a late event in apoptosis | Q34431596 | ||
Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis. | Q34512913 | ||
Hyperglucagonemia and insulin-mediated glucose metabolism | Q34560371 | ||
The evolution of beta-cell dysfunction and insulin resistance in type 2 diabetes | Q34655580 | ||
Metabolic and molecular basis of insulin resistance | Q35148800 | ||
The BCL-2 family reunion | Q35568029 | ||
Studies of pancreatic alpha cell function in normal and diabetic subjects | Q35576866 | ||
Grb10 exceeding the boundaries of a common signaling adapter. | Q35650904 | ||
Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis | Q35995063 | ||
Grb10 and Grb14: enigmatic regulators of insulin action--and more? | Q36131371 | ||
The role of alpha-cell dysregulation in fasting and postprandial hyperglycemia in type 2 diabetes and therapeutic implications | Q36780425 | ||
The replication of beta cells in normal physiology, in disease and for therapy | Q36978813 | ||
Preservation of beta-cell function by targeting beta-cell mass | Q37116279 | ||
Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus | Q37141727 | ||
Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector | Q37251114 | ||
Current strategies for the inhibition of hepatic glucose production in type 2 diabetes | Q37410100 | ||
Adaptation of the exocrine pancreas to diet | Q37946535 | ||
The biochemistry of cell death by apoptosis | Q38008685 | ||
Grb10 and active Raf-1 kinase promote Bad-dependent cell survival | Q40126556 | ||
Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes | Q40156533 | ||
Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation | Q40742143 | ||
Lentiviral vectors--the promise of gene therapy within reach? | Q40934408 | ||
Insulin secretion and action in subjects with impaired fasting glucose and impaired glucose tolerance: results from the Veterans Administration Genetic Epidemiology Study | Q43959543 | ||
Glucagon dose-response curve for hepatic glucose production and glucose disposal in type 2 diabetic patients and normal individuals. | Q44117925 | ||
Role of hyperglucagonemia in maintenance of increased rates of hepatic glucose output in type II diabetics | Q44183858 | ||
Beta-cell dysfunction and glucose intolerance: results from the San Antonio metabolism (SAM) study | Q44686996 | ||
beta-Cell function in subjects spanning the range from normal glucose tolerance to overt diabetes: a new analysis | Q45105931 | ||
Intradermal injection of lentiviral vectors corrects regenerated human dystrophic epidermolysis bullosa skin tissue in vivo | Q45877035 | ||
Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors | Q45884182 | ||
Impaired glucose-induced glucagon suppression after partial pancreatectomy. | Q45985373 | ||
P433 | issue | 3 | |
P921 | main subject | pancreas | Q9618 |
Glucose | Q37525 | ||
glycobiology | Q899224 | ||
glucagon | Q28163629 | ||
P304 | page(s) | 719-728 | |
P577 | publication date | 2012-01-07 | |
P1433 | published in | Diabetologia | Q5270140 |
P1476 | title | Lentivirus shRNA Grb10 targeting the pancreas induces apoptosis and improved glucose tolerance due to decreased plasma glucagon levels | |
P478 | volume | 55 |