TDP-43 pathology in familial frontotemporal dementia and motor neuron disease without Progranulin mutations

scientific article

TDP-43 pathology in familial frontotemporal dementia and motor neuron disease without Progranulin mutations is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/BRAIN/AWM024
P698PubMed publication ID17360763
P5875ResearchGate publication ID6446002

P50authorH Jurgen SchelhaasQ114416529
P2093author name stringPieter A van Doorn
Harro Seelaar
John C van Swieten
Patrizia Rizzu
Wouter Kamphorst
Rob Willemsen
Benno Küsters
Danielle Majoor-Krakauer
Asma Azmani
Maarten C de Rijk
Ming ten Brummelhuis
Sonia Rosso
P433issuePt 5
P407language of work or nameEnglishQ1860
P921main subjectfrontotemporal dementiaQ18592
dementiaQ83030
motor neuron diseaseQ3221083
pathologyQ7208
P304page(s)1375-1385
P577publication date2007-03-14
P1433published inBrainQ897386
P1476titleTDP-43 pathology in familial frontotemporal dementia and motor neuron disease without Progranulin mutations
P478volume130

Reverse relations

cites work (P2860)
Q36165139A novel exon 2 I27V VCP variant is associated with dissimilar clinical syndromes
Q50350613Biology and Pathobiology of TDP-43 and Emergent Therapeutic Strategies.
Q48265074Brain ¹⁸F-FDG and ¹¹C-PiB PET findings in two siblings with FTD/ALS associated with the C9ORF72 repeat expansion.
Q47548699CXorf56, a dendritic neuronal protein, identified as a new candidate gene for X-linked intellectual disability.
Q38118236Clinical Subtypes of Frontotemporal Dementia
Q38109705Co-localization of Bunina bodies and TDP-43 inclusions in lower motor neurons in amyotrophic lateral sclerosis
Q26863439Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis
Q38262690Disease origin and progression in amyotrophic lateral sclerosis: an immunology perspective.
Q35776901Distinct clinical and pathological characteristics of frontotemporal dementia associated with C9ORF72 mutations
Q36741538Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation
Q37241079FTD and ALS: a tale of two diseases
Q33922335FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration
Q36417318Familial frontotemporal dementia with amyotrophic lateral sclerosis and a shared haplotype on chromosome 9p
Q37461525Fine structural analysis of the neuronal inclusions of frontotemporal lobar degeneration with TDP-43 proteinopathy.
Q38392876Frequency and clinical characteristics of progranulin mutation carriers in the Manchester frontotemporal lobar degeneration cohort: comparison with patients with MAPT and no known mutations
Q33830991Frequency of ubiquitin and FUS-positive, TDP-43-negative frontotemporal lobar degeneration
Q38005607Frontotemporal dementia as a frontostriatal disorder: neostriatal morphology as a biomarker and structural basis for an endophenotype.
Q48094135Hippocampal sclerosis in the parkinsonism-dementia complex of Guam: quantitative examination of neurons, neurofibrillary tangles, and TDP-43 immunoreactivity in CA1.
Q51973117Missense mutations in the progranulin gene linked to frontotemporal lobar degeneration with ubiquitin-immunoreactive inclusions reduce progranulin production and secretion.
Q33828911Modeling the association between 43 different clinical and pathological variables and the severity of cognitive impairment in a large autopsy cohort of elderly persons
Q37260852Mutations in progranulin (GRN) within the spectrum of clinical and pathological phenotypes of frontotemporal dementia
Q35592875On the development of markers for pathological TDP-43 in amyotrophic lateral sclerosis with and without dementia
Q37918720RNA-binding proteins with prion-like domains in ALS and FTLD-U.
Q24648173Rapamycin rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instability
Q34642738Review: transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration
Q35512201Rodent models of TDP-43 proteinopathy: investigating the mechanisms of TDP-43-mediated neurodegeneration
Q33896030Survival profiles of patients with frontotemporal dementia and motor neuron disease
Q39138644Synapse Dysfunction of Layer V Pyramidal Neurons Precedes Neurodegeneration in a Mouse Model of TDP-43 Proteinopathies.
Q41514570TAR DNA-binding protein-43 in amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and Alzheimer disease
Q24594172TARDBP mutation analysis in TDP-43 proteinopathies and deciphering the toxicity of mutant TDP-43
Q37733168TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration
Q28261458TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor
Q37183193TDP-43: a novel neurodegenerative proteinopathy
Q89497713The Role of RNA Binding Proteins for Local mRNA Translation: Implications in Neurological Disorders
Q39657178The clinical and pathological phenotype of C9ORF72 hexanucleotide repeat expansions.
Q24615201The genetics and neuropathology of frontotemporal lobar degeneration
Q36926070The genetics of frontotemporal lobar degeneration
Q36485513The molecular basis of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum
Q30495415The spectrum of mutations in progranulin: a collaborative study screening 545 cases of neurodegeneration
Q37064056The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases
Q42461104Transactivation response DNA-binding protein 43 microvasculopathy in frontotemporal degeneration and familial Lewy body disease
Q33548806Transgenic rat model of neurodegeneration caused by mutation in the TDP gene.
Q41878973Tunicamycin produces TDP-43 cytoplasmic inclusions in cultured brain organotypic slices
Q37205729Update on recent molecular and genetic advances in frontotemporal lobar degeneration
Q33511759Variation at GRN 3'-UTR rs5848 is not associated with a risk of frontotemporal lobar degeneration in Dutch population.

Search more.