LKB1 regulates neuronal migration and neuronal differentiation in the developing neocortex through centrosomal positioning.

scientific article

LKB1 regulates neuronal migration and neuronal differentiation in the developing neocortex through centrosomal positioning. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.1938-07.2007
P932PMC publication ID6673218
P698PubMed publication ID17959818

P50authorKamon SanadaQ59297603
P2093author name stringYoshitaka Fukada
Naoyuki Asada
P2860cites workGSK3beta and PKCzeta function in centrosome localization and process stabilization during Slit-mediated neuronal repolarizationQ40282507
Cortical development: View from neurological mutants two decades laterQ40441433
Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activityQ40610701
Transcriptional regulation of cortical neuron migration by POU domain factorsQ40748974
G protein betagamma subunits and AGS3 control spindle orientation and asymmetric cell fate of cerebral cortical progenitorsQ42481073
Neurons tend to stop migration and differentiate along the cortical internal plexiform zones in the Reelin signal-deficient miceQ44121435
The Golgi apparatus and the centrosome are localized to the sites of newly emerging axons in cerebellar granule neurons in vitroQ48392137
Par6alpha signaling controls glial-guided neuronal migration.Q50790008
Identification of genes required for cytoplasmic localization in early C. elegans embryosQ68273724
Ndel1 operates in a common pathway with LIS1 and cytoplasmic dynein to regulate cortical neuronal positioningQ80841047
Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarityQ28568803
Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3beta and its upstream regulatorsQ28582775
Serine 732 phosphorylation of FAK by Cdk5 is important for microtubule organization, nuclear movement, and neuronal migrationQ28586292
A NUDEL-dependent mechanism of neurofilament assembly regulates the integrity of CNS neuronsQ28586737
LKB1 and SAD kinases define a pathway required for the polarization of cortical neuronsQ28591764
Mammalian SAD kinases are required for neuronal polarizationQ28592313
Vascular abnormalities and deregulation of VEGF in Lkb1-deficient miceQ28594689
LKB1 (XEEK1) regulates Wnt signalling in vertebrate developmentQ34536922
Nucleokinesis in neuronal migrationQ36121319
Lis1 and doublecortin function with dynein to mediate coupling of the nucleus to the centrosome in neuronal migrationQ36322452
LKB1/STRAD promotes axon initiation during neuronal polarization.Q40136806
P433issue43
P407language of work or nameEnglishQ1860
P304page(s)11769-11775
P577publication date2007-10-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleLKB1 regulates neuronal migration and neuronal differentiation in the developing neocortex through centrosomal positioning
P478volume27

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cites work (P2860)
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Q40939218Apaf1-deficient cortical neurons exhibit defects in axonal outgrowth
Q28395380Arsenic inhibits neurite outgrowth by inhibiting the LKB1-AMPK signaling pathway
Q37204613Breaking the epithelial polarity barrier in cancer: the strange case of LKB1/PAR-4
Q28504481CAMDI, a novel disrupted in schizophrenia 1 (DISC1)-binding protein, is required for radial migration
Q40239029Caveat mTOR: aberrant signaling disrupts corticogenesis
Q36241082Cell confinement controls centrosome positioning and lumen initiation during epithelial morphogenesis.
Q37958903Cell-autonomous and cell-to-cell signalling events in normal and altered neuronal migration
Q39671279Centrosome Motility Is Essential for Initial Axon Formation in the Neocortex
Q37593372Coordinated cell motility is regulated by a combination of LKB1 farnesylation and kinase activity.
Q51738004DEPDC5 and NPRL3 modulate cell size, filopodial outgrowth, and localization of mTOR in neural progenitor cells and neurons.
Q38648132Decoding the molecular mechanisms of neuronal migration using in utero electroporation
Q28589960Dpy19l1, a multi-transmembrane protein, regulates the radial migration of glutamatergic neurons in the developing cerebral cortex
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Q93188524LKB1 deficiency promotes proliferation and invasion of glioblastoma through activation of mTOR and focal adhesion kinase signaling pathways
Q34163651LKB1 destabilizes microtubules in myoblasts and contributes to myoblast differentiation
Q36746175LKB1 kinase-dependent and -independent defects disrupt polarity and adhesion signaling to drive collagen remodeling during invasion
Q30596293LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues.
Q37829489LKB1 loss of function studied in vivo
Q37868986LKB1 signaling in advancing cell differentiation
Q39686425LKB1-mediated spatial control of GSK3beta and adenomatous polyposis coli contributes to centrosomal forward movement and neuronal migration in the developing neocortex.
Q37333592LKB1; linking cell structure and tumor suppression
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